2019
DOI: 10.2147/ccide.s209278
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<p>Effect of sodium ascorbate on bond strength and metalloproteinases activity in bleached dentin</p>

Abstract: AimThis study evaluated the effect of sodium ascorbate (SA) on the proteolytic activity of matrix metalloproteinases (MMPs) and investigated the related effects on the bond strength of bleached dentin.Materials and methodsEighty freshly extracted human third molars were randomly divided according to treatment (bleaching or SA application), type of analysis (microshear or measuring MMP activity), and post-bleaching time to assess bond strength (24 hrs or 30 days). Data from both analyses were subjected to one-w… Show more

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Cited by 7 publications
(9 citation statements)
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“…Sodium ascorbate is the most preferred and studied antioxidant in dental practice [34,35]. Most of the studies investigated its postbleaching effects on bonding, and its positive effects were confirmed on shear bond strength [36].…”
Section: Discussionmentioning
confidence: 99%
“…Sodium ascorbate is the most preferred and studied antioxidant in dental practice [34,35]. Most of the studies investigated its postbleaching effects on bonding, and its positive effects were confirmed on shear bond strength [36].…”
Section: Discussionmentioning
confidence: 99%
“…SA is biocompatible and hydrosoluble, enabling its widespread use in the food industry and for oral purposes (23). Also, there is evidence showing that SA does not negatively impact the activity of dentin metalloproteinases (24). Nonetheless, SA’s instability in the presence of water and oxygen, along with its yellow appearance (which could lead to staining of bleached enamel), appear as drawbacks of this antioxidant (25).…”
Section: Sodium Ascorbate (Sa)mentioning
confidence: 99%
“…The most accepted theory to explain the post-bleaching bond strength reduction is the presence of residual oxygen on the enamel surface and within its structure [ 15 ]. This may interfere with the monomer capillarity in the etched enamel, as well as the double bond conversion, compromising the polymer quality and thus the final adhesion [ 15 , 16 , 17 ]. With a 7-day delay, similar bond strength values to the control and non-bleached groups have been achieved [ 6 , 16 , 17 ].…”
Section: Discussionmentioning
confidence: 99%