<p>Lesser Sac Glomangiosarcoma With Simultaneous Liver And Lymph Nodes Metastases Mimicking Small Bowel Gastrointestinal Stromal Tumor; Immunohistochemistry And Empirical Chemotherapy</p>

Abstract

Glomangiosarcoma is a rare malignant mesenchymal tumor. Despite malignant histopathological feature of glomangiosarcoma, metastasis was observed extremely rare in these tumors. Moreover, malignant glomus tumor with stomach origination and simultaneous metastasis to liver and lymph nodes were not reported so far. This report presented a 57-year-old male patient with an exophytic gastric glomangiosarcoma in lesser sac and simultaneous liver and lymph node metastasis.

Unsuspected gastric glomus tumour

“…Wide local excision with negative margins is considered the treatment of choice for GGT. In cases of malignant GGTs, chemotherapy has been used following resection with varying degrees of success in several reports 27 28…”

Metastatic Malignant Gastric Glomus Tumour: Multidisciplinary Diagnosis &amp; Treatment of a Rare Clinical Entity

“…[5] Only 15 prior cases of gastric glomus tumour with metastases to extra-gastric sites have been reported. [5][6][7][8][9][10][11][13][14][15][16] Metastases have been reported to the colon, liver, pancreas, kidney, skin, and brain. Metastases have been documented as occurring at the time of initial presentation to 6 years after diagnosis of the primary gastric glomus tumour.…”

“…Negahi and colleague advocate for tumour debulking and systemic chemotherapy. [14] They administered doxorubicin, bevacizumab and paclitaxel -chosen due to the vascular nature of the neoplasm. [14] Radiotherapy with concomitant cisplatin has also been tried.…”

“…[14] They administered doxorubicin, bevacizumab and paclitaxel -chosen due to the vascular nature of the neoplasm. [14] Radiotherapy with concomitant cisplatin has also been tried. [20] In the present case, guided by the limited evidence that exists, ve lines of palliative chemotherapy were tried including: doxorubicin, ifosfamide, docetaxel/gemcitabine, dacarbazine, and pazopanib.…”

“…[3] Malignant behaviour with distant metastases from the stomach is a rare occurrence of an already rare entity, with fewer than 15 cases described in the literature. [4][5][6][7][8][9][10][11][12][13][14][15][16] Here, we present the case of a 69-year-old male with a gastric glomus tumour with signi cant metastases to abdominal viscera requiring multidisciplinary care for diagnosis, surgical resection, and systemic treatment.…”