&lt;p&gt;Prevalence and Factors Associated with Neonatal Mortality at Ayder Comprehensive Specialized Hospital, Northern Ethiopia. A Cross-Sectional Study&lt;/p&gt;

Hadgu, Fikaden Berhe; Gebretsadik, Letekirstos Gebreegziabher; Mihretu, Hagos Gidey; Berhe, Amanuel Hadgu

doi:10.2147/phmt.s235591

Cited by 44 publications

(46 citation statements)

References 20 publications

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“…Similarly, in this study the odds of death among neonates who had early neonatal sepsis been 3.93 times that of neonates who did not have the conditions, and the odds of death which had late neonatal sepsis been 4.59 times that of neonates who did not have the conditions. This is consistent with studies conducted in Ghana, Gondar, and Mekele, Ethiopia [ 4 , 10 , 14 , 20 ]. The possible justification is that sepsis results in abscess formation, venous thrombosis, neurologic damage, and multi-organ dysfunction [ 35 ].…”

Section: Discussionsupporting

confidence: 92%

“…Similarly, neonates with a diagnosis of perinatal asphyxia had 3.85 times higher odds of death compared to those neonates without birth asphyxia. This is consistent with studies conducted in Ghana, Gondar, Mekele, and Jimma, Ethiopia [ 4 , 10 , 14 , 20 ]. The possible justification is that asphyxia causes carbon dioxide levels to increase and causing acidosis which leads to hypotension and ischemia then leads to brain cell injury then neonatal death [ 15 ].…”

Section: Discussionsupporting

confidence: 92%

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Neonatal mortality among neonates admitted to NICU of Hiwot Fana specialized university hospital, eastern Ethiopia, 2020: a cross-sectional study design

et al. 2021

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Background In Ethiopia, neonatal mortality is unacceptably high. Despite many efforts made by the government and other partners to reduce neonatal mortality; it has been increasing since 2014. Factors associated with neonatal mortality were explained by different researchers indifferently. There is no clear evidence to identify the magnitude of neonatal mortality and associated factors in the study area. The study aimed to assess the magnitude and factors associated with neonatal mortality. Methods Facility-based cross-sectional study was conducted among 834 randomly selected neonates. The study was conducted from February 20 to March 21, 2020. Data were extracted from medical records using a checklist adapted from the World Health Organization, and neonatal registration book. The data were inserted into Epi-data version 3.1 and then exported into SPSS window version 20 for analysis. Bivariate and multivariate analyses were employed to identify the association between independent variables and the outcome variable. Results Magnitude of neonatal mortality was 14.4% (95% CI:11.9,16.7). Being neonates of mothers whose pregnancy was complicated with antepartum hemorrhage [AOR = 4.13, 95%CI: (1.92,8.85)], born from mothers with current pregnancy complicated with pregnancy-induced hypertension [AOR = 4.41, 95%CI: (1.97,9.86)], neonates of mothers with multiple pregnancy [AOR = 2.87, 95% CI (1.08,7.61)], neonates delivered at the health center [AOR = 5.05, 95%CI: (1.72,14.79)], low birth weight [AOR = 4.01, 95%CI (1.30,12.33)], having perinatal asphyxia [AOR =3.85, 95%CI: (1.83,8.10)], and having early-onset neonatal sepsis [AOR = 3.93, 95%CI: (1.84,8.41)] were factors significantly associated with neonatal mortality. Conclusion The proportion of neonatal mortality was relatively in line with other studies but still needs attention. Antepartum hemorrhage, Pregnancy-induced hypertension, place of delivery, low birth weight, having perinatal asphyxia, and having neonatal sepsis were independent factors. The hospital, and health care workers should give attention to neonates admitted to intensive care units by strengthening the quality of care given at neonatal intensive care unit like infection prevention and strengthening early detection and treatment of health problems during Antenatal care visit.

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Section: Discussionsupporting

confidence: 92%

Section: Discussionsupporting

confidence: 92%

Neonatal mortality among neonates admitted to NICU of Hiwot Fana specialized university hospital, eastern Ethiopia, 2020: a cross-sectional study design

et al. 2021

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“…This study implied that there is a clear gap in the management and prevention of sepsis. Similarly in this study, 49% of neonates in this study had LBW and 35.5% of death was due to LBW, which is in line with the study done in Gondar [13] and Jimma [15] and Mekele [18]. This implies that the majority of causes of neonatal admissions were attributed to preventable and treatable neonatal conditions and can be prevented if care providers practice evidence-based interventions.…”

Section: Discussionsupporting

confidence: 89%

“…The odds of death among neonates who had neonatal sepsis were 2.48 times that of neonates who did not have the conditions. This is consistent with studies conducted in Ghana, Gondar, and Mekele, Ethiopia [10,13,18,19]. The possible justi cation is that sepsis results in abscess formation, venous thrombosis, neurologic damage, and multi-organ dysfunction [28].…”

Section: Discussionsupporting

confidence: 88%

Pattern, Causes, and Treatment Outcome of Neonates Admitted at Hiwot Fana Specialized University Hospital, Eastern Ethiopia.

Eyebru

Getachew

Debela

et al. 2021

Preprint

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Background: Neonatal period is the most the vulnerable time for survival of newborns. In Ethiopia, neonatal death remains increasing and requires extraordinary efforts and a novel intervention to reduced neonatal death as those deaths continue to occur in even hospital settings where there are the best neonatal care services. Despite many efforts done to improve the outcome of neonates admitted to hospitals; neonates continue dying in those settings. The causes of neonatal death in Ethiopia varies from place to place. So, identifying the causes of death in the study area is very important for prevention and treatment. The study aimed to assess the causes and factors associated with treatment outcomes. Methods: Institution-based cross-sectional study design was conducted among 707 randomly selected neonates from March 1 to 31, 2020. Data were extracted from medical records using a checklist adapted from WHO and neonatal registration book. The data were inserted into Epi-data version 3.1 and then exported into SPSS window version 22 for analysis. Bivariate and multivariate analyses were done to identify the association between independent variables and the outcome variable. Results: From 698 admitted neonates during 2 years period, 594 of them were improved and 104 of them were died. The proportion of neonatal death was 14.9% (95% CI:12.3,17.9). Neonatal sepsis, low birth weight and prematurity were the leading cause of neonatal death. Residency [ AOR=2.30, 95%CI: (1.3, 4.12)], low birth weight [AOR=2.52, 95%CI: (1.24,5.13))], respiratory distress syndrome [AOR =2.86, 95%CI:(1.11.7.35)], neonatal sepsis [AOR= 2.48, 95%CI: (1.40, 4.38)], and Neonates treated with phototherapy and oxygen [ AOR=0.22, 95%CI:(0.088,0.54)], [AOR= 0.47,95%CI:(0.22,0.99)] were factors associated with poor treatment outcome.Conclusion: The causes of neonatal death were mainly from preventable and treatable causes like neonatal sepsis, low birth weight, and prematurity in the study setting. Residency, low birth weight, respiratory distress syndrome, having neonatal sepsis, treatment with phototherapy, and treatment with oxygen were independent factors. The concerned bodies should give attention to neonates admitted to intensive care units by strengthening the quality of care given at the unit and strengthening early detection and prevention of neonatal problems during post-partum periods.

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“… 13 Jaundice was one of the most common causes of neonatal mortality and responsive for 6.7% of neonatal death in Ghana. 14 In Ethiopia, of the total death at Ayder, about 98.3% occurred during the first week of their life 15 and at Aroresa in Sidama, neonatal mortality was 41 per 1000 live birth and neonatal complication was one of the predictors for neonatal mortality. 16 In the northwest part of Ethiopia, the study revealed that Jaundice was one of the significant predictors for neonatal mortality, especially under 7 days of age.…”

Section: Introductionmentioning

confidence: 99%

Rate and Predictors of Neonatal Jaundice in Northwest Ethiopia: Prospective Cohort Study

Birhanu¹,

Atnaf²,

Molla³

et al. 2021

JMDH

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Background Neonatal jaundice is one of the most common clinical disorders occurred worldwide. About 1.1 million neonates develop jaundice per year globally and the vast majority of them found in sub-Saharan Africa and South Asia. There is a paucity of evidence on the incidence rate and predictors of neonatal jaundice in Ethiopia. Therefore, this study was aimed at determining the rate and predictors of neonatal jaundice in the northwest, Ethiopia. Methods A prospective cohort study design was conducted at Debre Markos comprehensive, specialized Hospitals using 334 neonates from October 1, 2019, to June 30, 2020. Using a systematic random sampling technique, the study subjects were drawn. Data were entered into the Epi-Data TM Version 4.2 and analyzed using STATA TM Version 14.0. The Kaplan-Meier survival curve was used to estimate the survival time. A generalized Log rank test was used to compare the survival curves of different categorical variables. Finally, both bi-variable and multivariable Cox-proportional hazards regression models were used to identify the predictors of neonatal jaundice. The Results The overall incidence rate of jaundice among neonates was 4.5 per 100 person-hours. Long duration of labor [ARR = 3.5; 95% confidence interval (CI), (2.8–8.7)], being male neonates [ARR= 5.2; 95% CI (3.5–7.3)], “O” blood group mothers [ARR = 4.5; 95% CI (3.4–10.3)], and having neonatal sepsis 3.4 [ARR=3.4; 95% CI: (2.5–6.1)] were predictors. Conclusion The incidence rate of jaundice was higher in this study than the finding of the previous one. Being male, prolonged duration of labor, “O” blood group mothers and sepsis were the significant predictors. Hence, an effort has to be made to decrease the incidence rate of neonatal jaundice through improving newborn care and timely intervention for neonates with sepsis and delivered at a long duration of time as well as the neonates born from “o” blood type mothers are our recommendation.

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<p>Prevalence and Factors Associated with Neonatal Mortality at Ayder Comprehensive Specialized Hospital, Northern Ethiopia. A Cross-Sectional Study</p>

Cited by 44 publications

References 20 publications

Neonatal mortality among neonates admitted to NICU of Hiwot Fana specialized university hospital, eastern Ethiopia, 2020: a cross-sectional study design

Neonatal mortality among neonates admitted to NICU of Hiwot Fana specialized university hospital, eastern Ethiopia, 2020: a cross-sectional study design

Pattern, Causes, and Treatment Outcome of Neonates Admitted at Hiwot Fana Specialized University Hospital, Eastern Ethiopia.

Rate and Predictors of Neonatal Jaundice in Northwest Ethiopia: Prospective Cohort Study

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