&lt;p&gt;Temporal Trends of the Incidence of Ischemic Heart Disease in Iran Over 15 Years: A Comprehensive Report from a Multi-Centric Hospital-Based Registry&lt;/p&gt;

Nouri, Fatemeh; Feizi, Awat; Taheri, Marzieh; Mohammadifard, Noushin; Khodarahmi, Somayeh; Sadeghi, Masoumeh; Sarrafzadegan, Nizal

doi:10.2147/clep.s259953

Cited by 11 publications

(6 citation statements)

References 29 publications

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“…Previous studies revealed that the highest impact attributed to PM 10 , with an attributable proportion of 7.037% (5.02–10.27), corresponding to an excess of 637 (435–890) hospital admission of all CVDs (ICD9: 390–459) in Isfahan, during our study period ( Kermani et al, 2018 ). Moreover, recent estimates indicated that in Isfahan, age-, sex-, and place-of-residence adjusted incidence rate (per 10,000) of ischemic heart disease in Isfahan were 41.23–59.92, based on different reference populations during the period between April 2010 to March 2012 ( Nouri et al, 2020 ). In addition, the prospective studies have highlighted a high incidence of various risk factors, including hypertension, obesity, metabolic syndrome, hypercholesterolemia, diabetes mellitus, hypertriglyceridemia, and smoking in Isfahan ( Sarrafzadegan et al, 2011 ; Sadeghi et al, 2014 ).…”

Section: Discussionmentioning

confidence: 99%

Effects of sulfur dioxide and particulate matter pollution on hospital admissions for hypertensive cardiovascular disease: A time series analysis

Nouri

Taheri²,

Ziaddini³

et al. 2023

Front. Physiol.

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Background and aims: Air pollution is a major environmental risk factor and the leading cause of disease burden with detrimental effects on cardiovascular systems. Cardiovascular diseases are predisposed by various risk factors, including hypertension, as the most important modifiable risk factor. However, there is a lack of sufficient data concerning the impact of air pollution on hypertension. We sought to study the associations of short-term exposure to Sulfur dioxide (SO2) and particulate matter (PM10) with the number of daily hospital admissions of hypertensive cardiovascular diseases (HCD).Methods: All hospitalized patients between March 2010 to March 2012 were recruited with the final diagnosis of HCD based on the International Classification of Diseases 10 (codes: I10-I15) from 15 hospitals in Isfahan, one of the most polluted cities in Iran. The 24-hour average concentrations of pollutants were obtained from 4 monitoring stations. In addition to single- and two-pollutant models, we used Negative Binomial and Poisson models with covariates of holidays, dew point, temperature, wind speed, and extracted latent factors of other pollutants controlling for multi-collinearity to examine the risk for hospital admissions for HCD affected by SO2 and PM10 exposures in the multi-pollutant model.Results: A total of 3132 hospitalized patients (63% female) with a mean (standard deviation) age of 64.96 (13.81) were incorporated in the study. The mean concentrations of SO2 and PM10 were 37.64 μg/m3 and 139.08 μg/m3, respectively. Our findings showed that a significantly increased risk of HCD-induced hospital admission was detected for a 10 μg/m3 increase in the 6-day and 3-day moving average of SO2 and PM10 concentrations in the multi-pollutant model with a percent change of 2.11% (95% confidence interval: 0.61 to 3.63%) and 1.19% (0.33 to 2.05%), respectively. This finding was robust in all models and did not vary by gender (for SO2 and PM10) and season (for SO2). However, people aged 35-64 and 18-34 years were vulnerable to SO2 and PM10 exposure-triggered HCD risk, respectively.Conclusions: This study supports the hypothesis of the association between short-term exposure to ambient SO2 and PM10 and the number of hospital admissions due to HCD.

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Section: Discussionmentioning

confidence: 99%

Effects of sulfur dioxide and particulate matter pollution on hospital admissions for hypertensive cardiovascular disease: A time series analysis

Nouri

Taheri²,

Ziaddini³

et al. 2023

Front. Physiol.

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“…In 2011 and 2012, the CVD, IHD, and stroke SMR reached the greatest reduction, respectively. The difference in mortality rates between intervention and control districts may be related to the impact of IHHP on the incidence and the prevalence of coronary artery disease (CAD) risk factors and lifestyle behaviors in both regions [14][15][16][17].…”

Section: Discussionmentioning

confidence: 99%

“…Since, sustainability of interventional programs requires to be evaluated [22], prior researches have shown that after the program ended in 2007, high number of IHHP interventions were sustainable and incorporated within the health care system and the community [8,23]. In addition, previous studies indicated the decreasing trend of age-, gender-, and place-of-residencestandardized IHD and stroke incidence in the intervention [14,15,24]. The changes in incidence rates could be due to the changes in known coronary risk factors in the population which is likely one of the implications of IHHP implementation [18].…”

Section: Discussionmentioning

confidence: 99%

Temporal Trends of cardiovascular disease Mortality in Central Iran between 2001 and 2018: The Impact of Isfahan Healthy Heart Program (IHHP)

Mehrabani-Zeinabad,

Hassannejad,

Nouri

et al. 2023

Preprint

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Background: Cardiovascular diseases (CVD) death, principally ischemic heart disease (IHD) and stroke, is the most common cause of mortality worldwide. We aim to determine the temporal trends in CVD mortality in two large districts that consist the intervention and control areas of the Isfahan Healthy Heart Program (IHHP) over a period of 18 years (2000-2018). Methods: The Iran Death Registration System (DRS), cemetery databank in Isfahan, and the population of the two areas based on housing censuses of Iran were used for this study. IHHP was a comprehensive community-based intervention program for non-communicable disease (NCD) prevention and control using population and high-risk approaches. It was performed in 2000-2007 in Isfahan and Arak districts as an intervention and control areas, respectively. Using interpolating approach, the population was estimated between census years. Incompleteness, misalignment, and misclassification in the DRS were considered and addressed accordingly. Direct method was applied to calculate age-, gender-, and residency-standardized mortality rates (SMR) based on reference population. Results: The overall age-, gender-, and residency-standardized CVD mortality rate decreased from 586.28 (95% confidence interval [CI]: 559.39-615.76) to 410.67 (95% CI: 394.62-427.51) per 100,000 in intervention area between 2002 and 2011, a reduction of approximately 29.95%. The similar trend was observed for IHD and stroke standardized mortality rate (SMR) by 44.62% and 40.68% reduction, respectively. Control area and national data showed a rise in SMR in the first years of study followed by slight reduction from 2006. However, SMR showed increasing trend after 2011 in all regions. Nevertheless, the control area witnessed higher SMR compared with intervention area. The SMR was higher among individuals aged >75 years and among men during the study period. Conclusion: A decreasing trend in the SMR over a period of 2002-2011 could be likely related to the IHHP comprehensive interventions that were implemented in intervention areas. These findings assert the significant role of performing such preventive strategies at the population level and high risk groups that could lead to decreasing the risk factors of CVD and ultimately impact it’s mortality.

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“…Detailed descriptions of the methods used in this project have been provided in previous reports. [ 19 ]…”

Section: Methodsmentioning

confidence: 99%

Presentation, Management and Early Mortality of Patients with Acute Coronary Syndrome in a Large Sample Study of a Middle East Country

Bahrani

Sadeghi

Teimouri-jervekani

et al. 2023

International Journal of Preventive Medicine

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Background: Due to lack of contemporary data on the presentation, management, and mortality of acute coronary syndrome (ACS) admissions in Iran, in this prospective registry study, we aimed to evaluate the presentation, management, and mortality as the outcome of patients with ACS in Isfahan, Iran, 2001–2016 to address treatment and healthcare depletions. Methods: Data of 62,276 patients admitted with the diagnosis of ACS from 2001 to 2016 prospectively were obtained by Surveillance Unit of Isfahan Cardiovascular Research Center, Isfahan, Iran, in 13 hospitals of Isfahan province. We evaluated data on presentation, management, and in-hospital and 28-day mortality. Results: Nearly half of the patients ranged in age from 51 to 70 years (32050, 51.5%), which did not differ among ACS types (ST-segment myocardial infarction (STEMI): 53.9%; non-STEMI: 53.4%; unstable angina: 51.9%). In-hospital, anti-platelets use was high (84.9%). Thrombolytic were used in 48.1% of STEMI, 3.8% of non-STEMI, and 1.1% of unstable angina. Discharge medication rates were suboptimal. In-hospital and 28-day mortality were highest for STEMI (6.5 and 12.6%, respectively). Conclusions: These data represent the large ACS registry in Iran. Data revealed the various presentations of ACS and demonstrated opportunities for improving ACS management by focusing on increasing use of recommended drugs especially after discharge due to suboptimal medical treatment in these patients. The high mortality rate needs to be taken into consideration in ACS patients.

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<p>Temporal Trends of the Incidence of Ischemic Heart Disease in Iran Over 15 Years: A Comprehensive Report from a Multi-Centric Hospital-Based Registry</p>

Cited by 11 publications

References 29 publications

Effects of sulfur dioxide and particulate matter pollution on hospital admissions for hypertensive cardiovascular disease: A time series analysis

Effects of sulfur dioxide and particulate matter pollution on hospital admissions for hypertensive cardiovascular disease: A time series analysis

Temporal Trends of cardiovascular disease Mortality in Central Iran between 2001 and 2018: The Impact of Isfahan Healthy Heart Program (IHHP)

Presentation, Management and Early Mortality of Patients with Acute Coronary Syndrome in a Large Sample Study of a Middle East Country

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