“…As far as we know, many clinical effects of laser irradiation depend on the changes in functional condition of blood cell and plasma coagulant factors, which in the first instance are under the influence of LPLR in its intravascular application. 23,29,30 Using of ILIB with 2.0 mW power in intact animals finds its mechanism of anticoagulation influence on vascular endothelium, blood cells, what is demonstrated by marked prolongation of APTT characterizing the internal intravascular way of blood coagulation. The considerable TT increasing and fibrinogen level decreasing can be explained by activated action of ILIB to proteins and enzymes of fibrinolysis system.…”