Luminescence response of an osmium(II) complex to macromolecular polyanions for the detection of heparin and chondroitin sulfate in biomedical preparations

Spectroscopic Sensing Characteristics of Novel Osmium Carbonyl Complexes to DNA and Other Polyanions

“…While [Os(phen) 2 (dppz)] 2+ is also a DNA light switching probe, its emission wavelength extends well into the infrared region [12]. We were interested in the photoluminescent property of [Os(phen) 2 CO(L)] 2+ complex series, where L is pyridine (py), 4-phenylpyridine (4-phpy) and triphenylphosphine (PPh 3 ) due to their moderate to high photo emission ability in the visible region and their emission changes when polyanions such as heparin, carrageenan and chondroi-American Journal of Analytical Chemistry tin sulfate are present [26] [27]. The [Os(phen) 2 CO(4-phpy)] 2+ (Structure in Figure 1) showed the highest luminescence enhancement by these polyanions in ethanol as well as in aqueous solutions.…”

Multi-positively charged dendrimeric nanoparticles induced fluorescence quenching of graphene quantum dots for heparin and chondroitin sulfate detection

“…Several methods for monitoring highly negatively charged polyanions have been developed for these polysaccharides in commercial or clinical samples (Fu et al, 2012;Sun et al, 2006;Yu et al, 2009). In recent years, researchers have developed some fluorescence approaches for polyanions detection by electrostatic interaction (Cai et al, 2011;Dai et al, 2011;Kim et al, 2014;Wu et al, 2013). Even though some of these methods showed high sensitivity, most of their positively charged materials used for polyanions detection were insoluble in water and contained few positive charges, which extremely restricted their applications in detection fields.…”

Differential interactions of conjugated polymer nanoparticles with glycosaminoglycans in synthetic urine

“…Conventional GAG detection methods require sample preparation steps followed by complicated instrumental analysis or biochemical assays. [5][6][7][8][9] Recently, several researchers have developed conceptually important detection methods on the basis of pattern recognition using nanoparticles, conjugated polyelectrolytes, and liposomes. [10][11][12][13][14] In those examples, differentiation of GAGs was demonstrated by using multivariate statistical methods including linear discriminant analysis (LDA).…”