Luminescent chemosensors based on silicananoparticles for the detection of ionic species

Montalti, Marco; Rampazzo, Enrico; Zaccheroni, Nelsi; Prodi, Luca

doi:10.1039/c2nj40673j

Cited by 38 publications

(19 citation statements)

References 43 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In order to obtain more efficient, selective, and sensitive chemosensors, an increasing number of papers have recently appeared in which the chemosensor is anchored to different nanosized supports [83][84][85][86]. One of them, boehmite nanoparticles, which is an aluminum oxyhydroxide (γ-AlO(OH)), presents different advantages such as the possibility to make fluorescence emission studies in pure water with little scattering, and the recovering of the sensor system after their use by centrifugation because a change from a sol to a gel state occurs at basic pH.…”

Section: Grafted Polyamine Derivativesmentioning

confidence: 99%

Fluorescent Chemosensors Based on Polyamine Ligands: A Review

et al. 2021

View full text Add to dashboard Cite

Polyamine ligands are water-soluble receptors that are able to coordinate, depending on their protonation degree, either metal ions, anionic, or neutral species. Furthermore, the presence of fluorescent signaling units allows an immediate visual response/signal. For these reasons, they can find applications in a wide variety of fields, mainly those where aqueous media is necessary, such as biological studies, wastewater analysis, soil contamination, etc. This review provides an overview of the recent developments in the research of chemosensors based on polyamine ligands functionalized with fluorescent signaling units. The discussion focuses on the design, synthesis, and physicochemical properties of this type of fluorescent chemosensors in order to analyze the applications associated to the sensing of metal ions, anions, and neutral molecules of environmental and/or biological interest. To facilitate a quick access and overview of all the chemosensors covered in this review, a summary table of the chemosensor structures and analytes, with all the corresponding references, is also presented.

show abstract

Section: Grafted Polyamine Derivativesmentioning

confidence: 99%

Fluorescent Chemosensors Based on Polyamine Ligands: A Review

et al. 2021

View full text Add to dashboard Cite

show abstract

“…A leading part in the development of fluorescent nanoparticles obtained by the Pluronic F127 micelle assisted method was played by our group. 12 These nanoparticles were recently reported with the acronym PluS NPs (Pluronic Silica NanoParticles) 119 and we exploited the versatility of these systems in several fields spanning from photophysical studies, 17,119 sensors, 41,120 imaging, 115 fluorescentphotoswitchable nanoparticles, 121 and ECL. 21,79 From a morphological point of view, these NPs had a silica core of about 10 nm, and an overall hydrodynamic diameter of about 25 nm.…”

Section: Direct Micelle Assisted Methodsmentioning

confidence: 99%

“…[30][31][32][33][34][35][36][37][38][39] Nevertheless, in our opinion, dye-doped silica nanoparticles (DDSNs) are a very successful example, capable of offering all the required features to obtain very effective tools for diagnostic and theranostic applications. 12,18,26,[40][41][42][43][44] Their synthetic versatility, in fact, allows the preparation of multifunctional targeted nanosystems (Fig. 1).…”

Section: Prodimentioning

confidence: 99%

“…238 In this context, luminescent silica nanoparticles can offer interesting solutions, 55,239,240 overcoming many of the typical limitations of conventional chemosensors. 12,236,[241][242][243][244][245][246] We have already discussed some select examples of chemosensors based on luminescent DDSNs, 41 which can be used to monitor the concentration in cells, in particular of metal ions that act as biomarkers of specific diseases and/or to understand their pathogenic mechanisms. We would particularly like to stress here, together with the favourable properties that we have discussed so far, some of the unique advantages that DDSNs can offer in the field of sensing.…”

Section: Luminescent Nanoparticles As Chemosensorsmentioning

confidence: 99%

See 1 more Smart Citation

Dye-doped silica nanoparticles as luminescent organized systems for nanomedicine

et al. 2014

View full text Add to dashboard Cite

The ability to find synergic solutions is the core of scientific research and scientific advancement. This is particularly true for medicine, where multimodal imaging and theranostic tools represent the frontier research. Nanotechnology, which by its very nature is multidisciplinary, has opened up the way to the engineering of new organized materials endowed with improved performances. In particular, merging nanoparticles and luminescent signalling can lead to the creation of unique tools for the design of inexpensive, hand-held diagnostic and theranostic kits. In this wide scenario, dye-doped silica nanoparticles constitute very effective nanoplatforms to obtain efficient luminescent, stable, biocompatible and targeted agents for biomedical applications. In this review we discuss the state of the art in the field of luminescent silica-based nanoparticles for medical imaging, starting with an overview of the most common synthetic approaches to these materials. Trying to rationalize the presentation of this extremely multifaceted and complex subject, we have gathered significant examples of systems applied in cancer research, also discussing those that take a multifunctional approach, including theranostic structures. Nanoprobes designed for applications that do not include cancer are a minor part, but interesting achievements have been published and we present a selection of these in the subsequent section. To conclude, we propose a debate on the advantages of creating chemosensors based on luminescent silica nanoparticles. This is far from easy but is a particularly valuable goal in the medical field and therefore subject to extensive research worldwide.

show abstract

“…As mentioned, however, most of the possible sensing applications of this species should be in pure water and, due to the very poor solubility of L in this solvent, we decided to use silica corepolyethylene glycol (PEG) shell nanoparticles (NPs) as vehicles and incubators to host L and favor the Pd II binding events in water. 6,7 Since a few years, we have been actively developing, and satisfactorily applying in many fields, very stable and highly water soluble nanoparticles presenting a hard silica core of 10 nm of diameter surrounded by a soft PEG shell 7 nm thick, for a total average hydrodynamic diameter of ca. 25 nm.…”

mentioning

confidence: 99%

A fluorescent ratiometric nanosized system for the determination of Pd^II in water

et al. 2014

Self Cite

View full text Add to dashboard Cite

show abstract

Luminescent chemosensors based on silicananoparticles for the detection of ionic species

Cited by 38 publications

References 43 publications

Fluorescent Chemosensors Based on Polyamine Ligands: A Review

Fluorescent Chemosensors Based on Polyamine Ligands: A Review

Dye-doped silica nanoparticles as luminescent organized systems for nanomedicine

A fluorescent ratiometric nanosized system for the determination of Pd^II in water

Contact Info

Product

Resources

About

Luminescent chemosensors based on silicananoparticles for the detection of ionic species

Cited by 38 publications

References 43 publications

Fluorescent Chemosensors Based on Polyamine Ligands: A Review

Fluorescent Chemosensors Based on Polyamine Ligands: A Review

Dye-doped silica nanoparticles as luminescent organized systems for nanomedicine

A fluorescent ratiometric nanosized system for the determination of PdII in water

Contact Info

Product

Resources

About

A fluorescent ratiometric nanosized system for the determination of Pd^II in water