2004
DOI: 10.1166/jnn.2004.017
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Luminescent Nanoparticle Probes for Bioimaging

Abstract: Bioimaging with luminescent nanoparticle probes have recently attracted widespread interest in biology and medicine. In comparison with commonly used organic dyes, luminescent nanoparticles are better in terms of photostability and sensitivity. These optical features of nanoparticle probes are critical for real time tracking and monitoring of biological events in the cellular level, which may not be accomplished using regular fluorescent dyes. Nanoparticle probes are also shown highly suitable for immunoassay … Show more

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Cited by 82 publications
(45 citation statements)
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“…Dye-doped FSNPs have shown a great promise as highly sensitive and photostable fluorescent probes [29][30][31][32][33][34]. During the FSNP synthesis, thousands of dye molecules are doped inside the silica matrix.…”
Section: Introductionmentioning
confidence: 99%
“…Dye-doped FSNPs have shown a great promise as highly sensitive and photostable fluorescent probes [29][30][31][32][33][34]. During the FSNP synthesis, thousands of dye molecules are doped inside the silica matrix.…”
Section: Introductionmentioning
confidence: 99%
“…The labeled antibodies can then be used in various assays to identify specific pathogens, molecules or structures. Example of nanoparticle technology includes the use of gold nanoparticles, nanobarcodes, quantum dots and nanoparticle probes (Santra et al, 2004;Zhao et al 2004). Additional nanotechnologies include nanopores, cantilever arrays, nanosensors and resonance light scattering.…”
Section: Nucleicmentioning
confidence: 99%
“…Luminescent nanoparticles have been shown to have better photostability and sensitivity than organic dyes (Santra et al, 2004). The nanoparticles used for probing and labeling include quantum dots, colloidal gold and silver, polymer beads, dye-doped nanoparticles, and organic nanoparticles (Seydack, 2005).…”
Section: Optical Sensingmentioning
confidence: 99%