Lung cancer associated with Sweet’s syndrome: Report of a case

Abstract

Lung cancer associated with Sweet's syndrome is extremely rare. There are only seven reports of such cases. As far as could be determined from a comprehensive search, there is no reported operative case of lung cancer with this syndrome in the world literature. A 75-year-old Japanese man was diagnosed as having Sweet's syndrome. A chest computed tomography (CT) scan to screen for malignant lesions associated with this syndrome revealed an abnormal shadow in the lung. Although [(18)F]2-fluoro-2-deoxy-D: -glucose positron emission tomography showed no abnormal uptake, lung cancer was most strongly suspected by chest CT. His erythema improved rapidly with steroid therapy and he underwent a segmentectomy (S(6)) of the right lower lobe. A pathological examination revealed lung adenocarcinoma (pT1N0M0: Stage Ia). The patient was discharged from the hospital without any worsening of Sweet's syndrome. We herein report a first operative case of an early stage lung adenocarcinoma with this syndrome.

Nadir Görülen Bir Paraneoplastik Sendrom; Sweet Sendromu

“…Bazı hastalarda rekürrensleri engellemek için 10-30 mg dozlarında 2 ile 3 aya kadar tedavi uygulamak gerekebilir (22). Eğer tedaviye cevap alınamazsa indometazin, siklosiporin veya dapson alternatif olarak verilebilir (23). Vakamızda; nadir görülen Sweet Sendromu yine nadir olarak görülen karaciğer metastazlı akciğer nöroendokrin tümörüne bağlı paraneoplastik olarak karşımıza çıkmaktadır.…”

“…Pubmed üzerinden günümüze kadar yapılan literatür taramasında; akciğer maligniteli Sweet Sendromu nadir olup, toplam 8 tane Sweet Sendrom tanılı vakayı görmekteyiz (23,(25)(26)(27)(28)(29)(30)(31).…”

Pregnancy-associated Sweet’s Syndrome in an Acute Episode of Ulcerative Colitis

“…While the epidermis is usually preserved, the predominant cells comprising the infiltrate in the upper dermis of cutaneous Sweet's syndrome lesions are mature neutrophil granulocytes. Sweet's syndrome is frequently associated with malignancy [11] (e. g., acute leukaemia [12,13]), a drug-induced form often following administration of granulocyte-colony stimulating factor (G-CSF) [14] is also known. An idiopathic ("classic") form predominantly occurs in women aged 30 to 50 years and is frequently preceded by inflammation of the gastrointestinal or respiratory tract [15,16].…”

Multi-organ Involvement of Sweet's Syndrome: A Case Report and Literature Review

“…The first case of SS was reported by Robert Sweet in 1964 and was originally described as acute febrile neutrophilic dermatosis (3). Based on the etiological factors of SS, the condition is now classified into classical/idiopathic, drug-induced and malignancy-associated subtypes (4)(5)(6)(7)(8)(9)(10)(11). SS occurs worldwide, with no significant regional or racial differences (12,13).…”