Lung homotransplantation in man

Hardy, James D.; Webb, Watts R.; Dalton, M. L.; Walker, Garry

doi:10.1097/00007890-196411000-00039

Cited by 52 publications

(50 citation statements)

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“…Although the patient died of renal failure after 3 weeks, the case is notable because the lung was donated after circulatory death (DCD) and early function of the lung was excellent. 12 Progress over the next 15 yr was dogged by airway healing complications and the longest survivor, that of Derom in Belgium, lived only 6 months. Reitz and colleagues 13 performed the first successful heart -lung transplant in 1981 and the Toronto group achieved successful singlelung transplantation a few years later.…”

Section: Heart Transplantationmentioning

confidence: 99%

Organ transplantation: historical perspective and current practice

Watson

Dark

2012

British Journal of Anaesthesia

206

143

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Over the course of the last century, organ transplantation has overcome major technical limitations to become the success it is today. The breakthroughs include developing techniques for vascular anastomoses, managing the immune response (initially by avoiding it with the use of identical twins and subsequently controlling it with chemical immunosuppressants), and devising preservation solutions that enable prolonged periods of ex vivo storage while preserving function. One challenge that has remained from the outset is to overcome the shortage of suitable donor organs. The results of organ transplantation continue to improve, both as a consequence of the above innovations and the improvements in peri- and postoperative management. This review describes some of the achievements and challenges of organ transplantation.

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Section: Heart Transplantationmentioning

confidence: 99%

Organ transplantation: historical perspective and current practice

Watson

Dark

2012

British Journal of Anaesthesia

206

143

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“…The first lung transplantation was performed with an organ recovered from a donation after circulatory death (DCD) donor . Renewed interest in DCD lung transplantation was raised in the 1995 following the publication by D'Alessandro and co‐workers in which they reported the first successful DCD donor lung transplantations as part of an institutional DCD program .…”

Section: Introduction/backgroundmentioning

confidence: 99%

DCD lung donation: donor criteria, procedural criteria, pulmonary graft function validation, and preservation

et al. 2016

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SUMMARYIn an era where there is a shortage of lungs for transplantation is increased utilization of lungs from donation after circulatory death (DCD) donors. We review the reports of 11 controlled and 1 uncontrolled DCD programs focusing on donor criteria, procedural criteria, graft assessment, and preservation techniques including the use of ex vivo lung perfusion. We have formulated conclusions and recommendations for each of these areas, which were presented at the 6th International Conference on Organ Donation. A table of recommendations, the grade of recommendations, and references are provided.

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“…At the initial lung transplantation, performed on June 11, 1963, Drs. James D. Hardy and Watts R. Webb at the University of Mississippi were limited to azathioprine, prednisone, and cobalt . Nearly two decades later, on March 9, 1981, Drs.…”

mentioning

confidence: 99%