Lung perfusion studies after transcatheter closure of persistent ductus arteriosus with the Amplatzer duct occluder

Abstract

The incidence of abnormal left lung perfusion is high 6 months after transcatheter closure of PDA with the ADO, more likely in the low weight symptomatic infants and in patients with a short duct or a relatively shallow duct having abrupt narrowing of a large ampulla.

Early predictive echocardiographic features of hemodynamically significant patent ductus arteriosus in preterm VLBW infants

“…noted a clear pathological ductal type. Patients with PDA who had undergone ductal ligation or who were diagnosed in infancy usually had short ductal length . In the present study, ductal length ranged from 2.5 to 5.3 mm, and significant narrowing of the pulmonary arterial end of the PDA was noted in only one patient.…”

Use of the Amplatzer Vascular Plug II Device to Occlude Different Types of Patent Ductus Arteriosus in Pediatric Patients

“…This raise our concerns about the excessive length of this device when dealing with large PDA in small infants with an infrequently but real risk to occlude the left pulmonary artery take off with the device proximal disc. Recently, a report was published on the long‐term pulmonary blood flow in patients who underwent PDA device closure with the ADO devices, suggesting this would not be a problem exclusively related to the AVP II device but related to the procedure itself when using devices for PDA closure. This complication seems to be anyway unusual and was reported to resolve on its own in the majority of cases, therefore, it is not contraindicated to use it for closure of large PDAs in small infants.…”

Long-term Follow-up Results of Lung Perfusion Studies after Transcatheter Closure of Patent Ductus Arteriosus

“…Left lung perfusion abnormalities that develop as a result of PDA closure using ADO devices have been linked to young age and low weight . A ductus ampulla size smaller than 5.8 mm was reported to have 90% sensitivity and 81% specificity for predicting LLP abnormalities in a series of 47 cases that used ADO for PDA closure . In our study, patients whose LLP returned to normal and those whose LLP abnormality persisted showed no difference in terms of age, sex, weight, BSA, D1, D1/BSA, or D2/L at the time of PDA closure or the second scintigraphy.…”

“…Polat et al. report decreased LLP during short‐ and midterm follow‐up in 17 out of 47 patients . Kramoh et al.…”