Lung Transplantation Outcome in Cystic Fibrosis Patients With Previous Pneumothorax

Lung Transplantation in Older Patients With Cystic Fibrosis: Analysis of UNOS Data

“…[1][2][3][4][5] Because of this trend, cardiothoracic surgeons are now experiencing increased numbers of adult CF patients presenting for lung transplantation (LTx).…”

Mechanical pleurodesis is not a contraindication to lung transplantation

“…Six relevant studies evaluating lung transplant outcomes following pleurodesis in specific populations were returned, two of which address the issue in patients with a history of cystic fibrosis, and three of which focus on patients with lymphangioleiomyomatosis-two lung diseases with a predilection for recurrent pneumothoraces. [1][2][3][4][5] An UpToDate search with similar keywords yielded general guidelines for lung transplant recipient selection, including special considerations such as previous cardiothoracic surgery. One cited article was a consensus for the selection of lung transplant candidates from the Pulmonary Transplantation Council of the International Society of Heart and Lung Transplantation, which lead to discovery of two additional large-volume, single-institution studies on lung transplantation in patients having previously undergone cardiothoracic surgical procedures.…”

Current status of lung transplantation

“…Experienced centres review cases on an individual basis. 9,15 Collagen vascular/connective tissue disease These patients remain controversial due to the concerns that extrapulmonary manifestations of disease might increase the risks of complications, particularly the increased oesophageal dysmotility associated with scleroderma. However, several studies have shown that in selected patients with scleroderma, 1-and 2-year survival is comparable with other groups.…”