Lupoid cutaneous leishmaniasis: A report of 16 cases

Bari, Arfan ul; Raza, Naeem

doi:10.4103/0378-6323.58698

Cited by 35 publications

(47 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The clinical course of lupoid CL is considered to be associated with changes in the cell-mediated immunity. A possible underlying pathogenetic mechanism involves changes in Th1 and Th2 cell responses and interleukin 4 (IL-4) production 8 . The altered host immune response then contributes to the high sensitivity to parasitic infections and extraordinary clinical presentations 8 .…”

Section: Discussionmentioning

confidence: 99%

“…Clinically, lupoid CL may particularly resemble lupus erythematosis and lupus vulgaris 8 . It may also resemble other granulomatous diseases of infectious or inflammatory origin and may mimic them; however, microscopic and histopathological findings are important in differentiating them from other dermatoses 9 .…”

Section: Discussionmentioning

confidence: 99%

“…8 evaluated 16 patients with lupoid CL and reported 4 different morphological patterns, including psoriasiform lesions, ulcerated/crusted lesions and discoid lupus erythematosis. Douba et al .…”

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Case Report: Lupoid cutaneous leishmaniasis mimicking verruca plana

et al. 2017

View full text Add to dashboard Cite

Cutaneous leishmaniasis (CL) is an infectious disease caused by various species of leishmania protozoan parasites. Lupoid CL is a rare form of CL that has a stunning similarity to other granulomatous cutaneous conditions of infectious or inflammatory origin. Verruca plana, also known as a “flat wart”, is a benign proliferation of the skin resulting from infection with human papilloma virus (HPV). Herein, we presented a case of lupoid CL mimicking verruca plana on the face.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Case Report: Lupoid cutaneous leishmaniasis mimicking verruca plana

et al. 2017

View full text Add to dashboard Cite

show abstract

“…The different clinical presentations depend mostly on the host immune response rather than on the causative species. However, there are some expressions that are more prevalent in one species than in another [6,7]. Unusual clinical variants of CL include mucocutaneous leishmaniasis (MCL), diffuse cutaneous leishmaniasis (DCL), and leishmaniasis recidivans (LR).…”

Section: Introductionmentioning

confidence: 99%

Leishmaniasis recidivans in Ethiopia: cutaneous and mucocutaneous features

Dassoni

Daba

Naafs³

et al. 2017

J Infect Dev Ctries

View full text Add to dashboard Cite

Cutaneous leishmaniasis (CL) is endemic in Ethiopia. An unusual clinical form of this disease is leishmaniasis recidivans (LR), a prolonged, relapsing form of cutaneous leishmaniasis resembling tuberculosis of the skin that may persist for many years with a chronic and relapsing course. This rare variant has been shown to be caused by Leishmania tropica species in the Old World and by Leishmania braziliensis, Leishmania amazonensis, Leishmania panamensis, and Leishmania guyanensis in the New World, as reported in various studies. To our knowledge, there are no reports from Ethiopia, and mucocutaneous involvement of LR has not been described to date. This was a retrospective analysis of the patients seen at the Italian Dermatological Center in Mekelle on the Tigrean highlands over a threeyear period (2008)(2009)(2010)(2011). Seven patients with typical clinical features of LR were seen. Two of them presented with signs of mucosal involvement. To date, Leishmania aethiopica is shown to be the only species causing CL that is endemic in the Ethiopian highlands. Therefore, it had to be assumed that the lesions in these patients were caused by this species. The aims of this communication are to report, for the first time, the presence of LR, most likely due to Leishmania aethiopica, in Ethiopia, and to report mucosal involvement in this rare clinical form of CL.

show abstract

“…Clinical patterns tend to be poor indicators of the species responsible. Other factors, such as parasitic load and, particularly, the host immune response are the determining factors (4,5).…”

mentioning

confidence: 99%

Cutaneous and Mucocutaneous Leishmaniasis Resembling Borderline-tuberculoid Leprosy: A New Clinical Presentation?

Dassoni¹,

Abebe²,

Naafs³

et al. 2013

Acta Derm Venerol

View full text Add to dashboard Cite

Both cutaneous and mucocutaneous leishmaniasis are endemic in Northern Ethiopia. The different clinical presentations depend on the responsible organism and the host's immune response. Localized cutaneous leishmaniasis is the type most frequently seen. Diffuse cutaneous leishmaniasis is relatively rare and usually associated with mucous membrane involvement. Diffuse cutaneous leishmaniasis presents with multiple lesions, can be difficult to diagnose and responds less favourably to treatment. We report here 2 patients with unusual presentations of diffuse cutaneous leishmaniasis presenting with large hypopigmented skin lesions mimicking borderline-tuberculoid leprosy. To our knowledge this presentation has not been described before and may present difficulties in making a definite diagnosis in regions where both leprosy and cutaneous leishmaniasis are endemic. Lepromatous leprosy and diffuse cutaneous leishmaniasis are regularly confused, particularly when no skin smears for acid-fast bacillus or Leishman-Donovan bodies are performed.

show abstract

Lupoid cutaneous leishmaniasis: A report of 16 cases

Abstract: Lupoid CL is not strictly a chronic form of disease, which presents on the face from the very onset and shows no scarring or recurrence.

Cited by 35 publications

References 0 publications

Case Report: Lupoid cutaneous leishmaniasis mimicking verruca plana

Case Report: Lupoid cutaneous leishmaniasis mimicking verruca plana

Leishmaniasis recidivans in Ethiopia: cutaneous and mucocutaneous features

Cutaneous and Mucocutaneous Leishmaniasis Resembling Borderline-tuberculoid Leprosy: A New Clinical Presentation?

Contact Info

Product

Resources

About