Lupus erythematosus tumidus: an underestimated entity

Teixeira, Miguel; Ferreira, Márcia; Alves, Rute; Selores, Manuela

doi:10.1191/0961203306lu2296cr

Cited by 9 publications

(7 citation statements)

References 17 publications

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“…(6) However, other authors have been unable to demonstrate mucin in JLIS. (2,11) in our case histopathology is in corealation with previous studies.…”

Section: Discussion: Jlis Described By Jessner and Kanof In 1953supporting

confidence: 68%

Jessners Lymphocytic Infiltration of Skin Sucessful Treatment With Prednisolone and Hydroxy Chloroquine

P¹,

Bonthu²,

Rama³

et al. 2015

jemds

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Jessners lymphocytic infiltration of the skin is a chronic, benign T-cell infiltrative disorder, usually manifesting as erythematous papules or plaques on the face, neck and back. we report the case of a 66-year -old man, who presented with erythematous papules and plaques on nose of 4 months duration and erythematous plaque on right arm of 1 month duration. skin biopsy confirmed the diagnosis of jessner's lymphocytic infiltration of the skin.The evolution was favorable with hydroxy chloroquine and prednisolone. KEYWORDS: Jessners lymphocytic infiltration of skin, hydroxy chloroquine and Prednisolone. INTRODUCTION:Jessner's lymphocytic infiltration of the skin (JLIS) is a skin condition of unknown aetiology characterized by erythematous papules and plaques located on the head, neck and upper back. The eruption resolves spontaneously after months or a few years but can recur for several years. A variety of empirical treatments has been tried with limited success. Here we report a case of jessners lymphocytic infiltration of skin successfully treated with hydroxychloroquine and prednisolone.

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“…(6) However, other authors have been unable to demonstrate mucin in JLIS. (2,11) in our case histopathology is in corealation with previous studies.…”

Section: Discussion: Jlis Described By Jessner and Kanof In 1953supporting

confidence: 68%

Jessners Lymphocytic Infiltration of Skin Sucessful Treatment With Prednisolone and Hydroxy Chloroquine

P¹,

Bonthu²,

Rama³

et al. 2015

jemds

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show abstract

“…Moreover, it is likely that skin lesions described under different designations, such as ‘urticarial plaque lupus erythematosus’, represent the same disease entity 13 . Therefore, LET has been underestimated and neglected in previous literature and has only recently been characterized thoroughly by clinical, photobiological, histological, immunohistochemical and serological features 14 . In 2000, our group analysed 40 patients with LET and defined diagnostic criteria for the classification of the disease 15 .…”

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confidence: 99%

Lupus erythematosus tumidus is a separate subtype of cutaneous lupus erythematosus

Schmitt¹,

Meuth²,

Amler

et al. 2009

British Journal of Dermatology

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Background Lupus erythematosus tumidus (LET) is a rare disease which was first described in 1909 but has not always been considered as a separate entity of cutaneous lupus erythematosus (CLE) in the international literature. Objectives To compare characteristic features of different subtypes of CLE and to analyse whether LET can be distinguished as a separate entity in the classification system of the disease. Methods The study involved 44 patients with CLE, including 24 patients with LET, 12 with discoid lupus erythematosus (DLE) and eight with subacute CLE (SCLE), from two centres in Germany. A core set questionnaire and an SPSS database were designed to enable a consistent statistical analysis. Results Location of skin lesions did not differ significantly between the CLE subtypes; however, the activity score was significantly lower in LET than in DLE (P < 0.01), and the damage score was significantly lower in LET than in SCLE (P < 0.01) and DLE (P < 0.01). Photosensitivity and antinuclear antibodies were confirmed to be different in LET compared with SCLE and DLE but without statistical significance. Moreover, histological analysis of skin biopsy specimens showed that abundant mucin deposition is significantly more present in LET compared with SCLE (P < 0.01) and DLE (P < 0.01) while prominent interface dermatitis and alteration of hair follicles were absent in LET. Conclusions Several significant differences were found between LET and other subtypes of CLE with regard to clinical, histological and laboratory parameters. These data strongly indicate that LET should be defined as a separate entity in the classification of CLE.

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“…(6) However, other authors have been unable to demonstrate mucin in JLIS. (2,11) in our case histopathology is in corelation with previous studies.…”

mentioning

confidence: 49%

Benign Lymphocytic Infiltration of Skin: A Case Report

P¹,

Rama²,

S³

et al. 2015

jemds

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Benign (Jessners) lymphocytic infiltration of the skin is a chronic, benign T-cell infiltrative disorder, usually manifesting as erythematous papules or plaques on the face, neck and back. We report the case of a 30-year -old female, who presented with erythematous papules and plaques on face, upper back, front of chest, of 4 months duration and erythematous plaque on both dorsa of hand and Fore arms of 1 month duration. Skin biopsy confirmed the diagnosis of jessner's lymphocytic infiltration of the skin. The evolution was favorable with hydroxy chloroquine.

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Lupus erythematosus tumidus: an underestimated entity

Cited by 9 publications

References 17 publications

Jessners Lymphocytic Infiltration of Skin Sucessful Treatment With Prednisolone and Hydroxy Chloroquine

Jessners Lymphocytic Infiltration of Skin Sucessful Treatment With Prednisolone and Hydroxy Chloroquine

Lupus erythematosus tumidus is a separate subtype of cutaneous lupus erythematosus

Benign Lymphocytic Infiltration of Skin: A Case Report

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