hemolytic crises in patients with hemoglobinopathies. 7,8 Few data about the lupus therapy with antimalarial drugs in children are available but there is not enough information about its prescription in patients with comorbidities, especially haemopaths. 4,5,9 Our experience showed that hydroxychloroquine has excellent clinical response and a good tolerance from pediatric patients, although β-thalassemia is a relative contraindication for it.