Lupus Symptoms Inventory (LSI): Development and Validation of a Self-evaluation Inventory of the Subjective Symptoms of Systemic Lupus Erythematosus

Peralta-Ramírez, María Isabel; Verdejo, Antonio J. Moreno; Muñoz, Miguel A.; Sabio, JM; Jiménez-Alonso, J; Pérez‐García, Miguel

doi:10.1007/s10880-007-9086-3

Cited by 10 publications

(8 citation statements)

References 13 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The lupus flare item was not included in the final set of 10 items in the LIT to remain consistent with the objective to develop an instrument that assesses the impact of lupus on a patient's life rather than measure the signs and symptoms of lupus. In addition, other more comprehensive patient‐reported instruments that measure the signs and symptoms of lupus exist ().…”

Section: Discussionmentioning

confidence: 99%

“…These disease activity indexes focus primarily on the clinical and/or laboratory aspects of SLE and may not necessarily help providers understand how and to what extent the disease impacts a patient's life. Several lupus‐specific PRO instruments have been developed, such as the Lupus Specific Symptom Checklist (), Systemic Lupus Erythematosus Needs Questionnaire (), Systemic Lupus Erythematosus Activity Questionnaire (), and Lupus Symptom Inventory (). However, these instruments are either very lengthy and burdensome for patients to complete, or they primarily focus on measuring the signs and symptoms of SLE rather than how SLE impacts a patient's life.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Development and Validation of the Lupus Impact Tracker: A Patient‐Completed Tool for Clinical Practice to Assess and Monitor the Impact of Systemic Lupus Erythematosus

Jolly

Garris

Mikolaitis

et al. 2014

Arthritis Care & Research

View full text Add to dashboard Cite

Objective. To derive and validate a brief patient-completed instrument, the Lupus Impact Tracker (LIT), to assess and monitor the impact of systemic lupus erythematosus (SLE). Methods. Items for the LIT were selected from the LupusPRO, a validated patient-reported outcomes measure, using 3 approaches: confirmatory factor analysis (CFA), stepwise regression, and patient focus groups. CFA was conducted to find items from the LupusPRO that fit a unidimensional structure to allow scoring as a single index. Stepwise regression methods identified items with the strongest relationship (convergent validity) with disease activity measures and patient health rating. Focus groups (n ‫؍‬ 26 patients) identified the most important items describing SLE impact. Selected items were evaluated for reliability and validity. Results. CFA found 21 items that fit a unidimensional structure. Stepwise regressions identified 15 of 21 items having good convergent validity with clinical measures. Patient focus groups identified 9 of 15 items as best capturing the impact of SLE. Overall, 7 items were selected across all 3 approaches (CFA, stepwise regression, and focus groups). Another 15 items were selected across 2 approaches. Through consensus with rheumatology clinician experts, a final set of 10 items was selected for the LIT. The LIT items showed good internal consistency (0.89) and test-retest reliabilities (0.87). Mean LIT scores differed significantly (P < 0.05) across criterion groups in the hypothesized direction, providing evidence of discriminant validity and responsiveness. Conclusion. The LIT is reliable and valid in SLE patients and offers a practical way for physicians and patients to assess and monitor the impact of SLE.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Development and Validation of the Lupus Impact Tracker: A Patient‐Completed Tool for Clinical Practice to Assess and Monitor the Impact of Systemic Lupus Erythematosus

Jolly

Garris

Mikolaitis

et al. 2014

Arthritis Care & Research

View full text Add to dashboard Cite

show abstract

“…Physician‐completed instruments used to assess SLE disease activity or organ damage focus primarily on clinical and/or laboratory findings in SLE, which may not necessarily reflect the extent to which the disease impacts the patient's life, are time‐consuming, and require training to complete. Several lupus‐specific patient‐reported outcome instruments have been developed ; however, these instruments are either very lengthy and may be burdensome for the patient to complete during routine use in clinical practice, or their primary focus is on measuring the signs and symptoms that SLE patients experience during a flare rather than on how SLE in general impacts the patient's life.…”

mentioning

confidence: 99%

Prospective Validation of the Lupus Impact Tracker: A Patient‐Completed Tool for Clinical Practice to Evaluate the Impact of Systemic Lupus Erythematosus

Jolly

Kosinski

Garris

et al. 2016

Arthritis & Rheumatology

View full text Add to dashboard Cite

College of Rheumatology Damage Index, and physician LIT feedback questionnaire. The reliability, convergent validity, construct validity, and responsiveness of the LIT were evaluated.Results. Of the 325 SLE patients enrolled, 90% were female, 53% were white, and 33% were African American. Their mean age was 42 years. The mean 6 SD baseline physician's global assessment and total SELENA-SLEDAI scores were 1.04 6 0.8 and 4.28 6 3.8, respectively, while 3-month scores were 0.94 6 0.73 and 4.09 6 3.79, respectively. Internal consistency reliability was high (>0.9) at both visits. LIT scores correlated highly with other measures of patient-reported outcomes, and construct validity was established against clinical measures. The LIT was highly responsive to patient-reported changes in SLE health status; however, LIT scores were not as responsive to changes in the SELENA-SLEDAI score. The majority of patients and physicians found LIT to be acceptable and feasible to administer in a clinical setting.Conclusion. The LIT is a reliable and valid instrument for assessing the impact of SLE on patients and captures unique and important information not included in physician assessments of disease. It may be useful in clinical practice to facilitate communication between the physician and the patient and enable efficient incorporation of the patient's perspective in disease management.Systemic lupus erythematosus (SLE) is a chronic autoimmune disease of unknown etiology that affects an estimated 161,000-322,000 people in the US (1,2). The prevalence of SLE is higher in women, usually in the childbearing years, and among minorities. The humanistic burden of SLE can also be significant, resulting in decreased quality of life and inability or decreased ability to work or perform daily activities. Studies have demonstrated that SLE patients have poorer functional status than the general population (3) and patients with other common chronic diseases (4).

show abstract

“…The subjects completed the following set of questionnaires at home during the week of the study: Pittsburgh Sleep Quality Index, PSQI [24]; Lupus Symptom Inventory, LSI [25]; Lupus Quality of Life, Lu-pusQoL [26]; McGill Pain Questionnaire-Short Form, MPQ-SF [27]; Multidimensional Fatigue Inventory, MFI [28]; and Hospital Anxiety and Depression Scale, HADS [29]. These questionnaires have already been validated and provide subjective information about the state of the person related with physical status, emotional state, self-confidence, working capacity, performance in carrying out activities, description and assessment of the pain, and sleep quality.…”

Section: Methodsmentioning

confidence: 99%

Using Actigraphy and mHealth Systems for an Objective Analysis of Sleep Quality on Systemic Lupus Erythematosus Patients

Balderas-Díaz

Martínez²,

Guerrero-Contreras³

et al. 2017

Methods Inf Med

View full text Add to dashboard Cite

The results indicate the need to complement the subjective evaluation of sleep with objective measures. The use of actigraphy in combination with a new mHealth system provides a complete assessment especially relevant to chronic conditions as SLE. Both systems incorporate this objective information directly from objective measures in a non-intrusive way. Moreover, the measures of bedroom environmental variables provide useful and relevant clinical information to assess what is happening daily and not occasionally. This could lead to more customized interventions and adapt the treatment to each individual.

show abstract

Lupus Symptoms Inventory (LSI): Development and Validation of a Self-evaluation Inventory of the Subjective Symptoms of Systemic Lupus Erythematosus

Cited by 10 publications

References 13 publications

Development and Validation of the Lupus Impact Tracker: A Patient‐Completed Tool for Clinical Practice to Assess and Monitor the Impact of Systemic Lupus Erythematosus

Development and Validation of the Lupus Impact Tracker: A Patient‐Completed Tool for Clinical Practice to Assess and Monitor the Impact of Systemic Lupus Erythematosus

Prospective Validation of the Lupus Impact Tracker: A Patient‐Completed Tool for Clinical Practice to Evaluate the Impact of Systemic Lupus Erythematosus

Using Actigraphy and mHealth Systems for an Objective Analysis of Sleep Quality on Systemic Lupus Erythematosus Patients

Contact Info

Product

Resources

About