Lutein-Enriched Emulsion-Based Delivery System: Impact of Casein-Phospholipid Emulsifiers on Chemical Stability

Abstract

The health benefits of carotenoids in terms of their role in decreasing the risk of diseases, particularly certain cancers and eye disease, are limited by their chemical degradation. Emulsion delivery systems with water dispersions of a carotenoid enhance chemical stability and bioavailability to the host. An emulsified carotenoid delivery system can be based on carotenoid dissolution in lipid media and its stabilization by a surfactant mixture of milk proteins (the caseins) and phospholipids. The inclusion of lutein into an emulsified delivery system comprised of bovine casein or caprine casein in combination with phospholipids (soybean lecithin) enhanced the chemical stability of lutein during storage for 7 days at pH 7.0 at incubation temperatures of 5 and 15°C. The chemical stability of lutein in the corn oil-in-water emulsions stabilized by bovine and caprine caseins in combination with soybean lecithin was in the following order: caprine α s1-II-casein/ lecithin > caprine α s1-I-casein/lecithin > bovine casein/lecithin. The results suggest that the chemical stability of lutein in oil-in-water emulsions can be enhanced by altering the thickness of the interfacial layer. Caprine casein/lecithin has the potential for use as an emulsifier in beverage emulsions.

Supramolecular Carotenoid Complexes of Enhanced Solubility and Stability—The Way of Bioavailability Improvement

“…The most commonly used protein-based emulsifiers in the food industry today are caseins and whey proteins, which are both food-grade proteins present in milk [97]. Sodium caseinate (SC) is its most common form of casein and is a good alternative for synthetic surfactants because it shows good thermal stability and prevents oxidation of the carotenoid and the emulsified oils.…”

Improved physicochemical stability of emulsions enriched in lutein by a combination of chlorogenic acid–whey protein isolate–dextran and vitamin E

“…Lutein, which is found in marigold flowers, has long been used as a natural, lipid‐soluble pigment. It was reported to have the potential benefits to human health for its antioxidant and antitumor capacity, and it can protect the DNA of photoreceptive cells from strong light and alleviate the UV damage to the skin (Mora‐Gutierrez, Attaie, & González, 2018; Rafi, Kanakasabai, Gokarn, Krueger, & Bright, 2015). Especially, lutein usually accumulates in the pigmented region and may reduce the morbidity of age‐related macular degeneration and cataracts (Gumus, Davidov‐Pardo, & McClements, 2016).…”