LXXXII The Inhibitory Effect of Adipose Tissue on Osteogenesis

Bioactive glass S53P4 in frontal sinus obliteration: A long‐term clinical experience

“…The overall complication rate was lower than previously described. 13,16 According to Montgomery and van Orman, 41 the osteoblastic theory of osteogenesis does not explain the frontal sinus bone formation, because the frontal sinuses are rendered free of periosteum and endosteum in obliterative frontal sinus surgery, and, thus, the osteogenesis probably occurs as a result of metaplasia of connective tissue. The present clinical long-term follow-up study reveals the histologic healing process in BAG-obliterated frontal sinuses.…”

Endoscopic Frontal Sinus Drainage Draf Type III with Mucosal Transplants

“…Montgomery, in his work on frontal sinus obliteration, found that covering bone with adipose tissue prevents the tendency for osteoneogenesis, so it seems reasonable to cover the bare bone with mucosal transplants to prevent major inflammation with scarring and osteoneogenesis and to facilitate rapid epithelialization. 12–14…”

“…11 Montgomery, in his work on frontal sinus obliteration, found that covering bone with adipose tissue prevents the tendency for osteoneogenesis, so it seems reasonable to cover the bare bone with mucosal transplants to prevent major inflammation with scarring and osteoneogenesis and to facilitate rapid epithelialization. [12][13][14] Keeping a wound moist leads to faster and better healing, less scarring, better esthetic outcome, and lower infection rates. 15 It seems reasonable that we can expect the same effect in sinus mucosa; however, up to now, there is only one uncontrolled study reporting a positive impact of moist wound healing after endonasal sinus surgery.…”