Lyme disease and seventh nerve paralysis in children

Prediction of Lyme Meningitis in Children From a Lyme Disease–Endemic Region: A Logistic-Regression Model Using History, Physical, and Laboratory Findings

“…5,7,13,14,[20][21][22][23] The etiology of a peripheral facial nerve palsy in children without Lyme disease includes a variety of infectious, neoplastic, structural, and idiopathic causes, most of which do not typically present with meningitis. [24][25][26][27] The only patient with AM in our study who had a cranial nerve palsy was found to have an abducens nerve palsy, which is also known to occur in Lyme disease, and was eventually diagnosed with multiple sclerosis. 13,17,21,28 Both peripheral facial nerve and abducens nerve palsy have been reported in children with Lyme disease who do not have a CSF pleocytosis or symptoms suggestive of meningitis.…”

Etiology of Aseptic Meningitis, Peripheral Facial Nerve Palsy, and a Combination of Both in Children

“…1,4 In contrast, in only a minority of patients with PFNP without aseptic meningitis and in patients with aseptic meningitis without PFNP was a specific etiology found. However, not all microbiologic tests were applied in all of these patients.…”

“…[1][2][3] Lyme borreliosis (caused by Borrelia burgdorferi sensu lato), the most common illness transmitted by ticks in Western Europe, has been held responsible in 2% to 50% of patients with PFNP depending on the study region and design, case definitions and diagnostic approach to Lyme borreliosis. 4,5 Aseptic meningitis is also a neurologic manifestation of Lyme borreliosis and, together with PFNP, is the predominant clinical feature of neuroborreliosis in children. 6,7 The most common etiologies of aseptic meningitis in children in Europe are enterovirus 8 and tick-borne encephalitis virus (TBEV) infections, especially in summer and early fall.…”

Surgical Treatment for Epstein-Barr Virus Otomastoiditis Complicated by Facial Nerve Paralysis: A Case Report of Two Young Brothers and Review of Literature

“…The main pathogens causing FNP in children are Borrelia burgdorferi (50%), idiopatic or Bell's palsy (26%), otitis media (OM) (12%), varicella-zoster virus (6%), Herpes simplex virus (4%), and coxsackie (2%) [2] . A thorough research of the literature showed that although rare, Epstein-Barr virus (EBV) can also be linked to FNP [3,4] .…”