Surgical Treatment for Epstein-Barr Virus Otomastoiditis Complicated by Facial Nerve Paralysis: A Case Report of Two Young Brothers and Review of Literature

Eeten, Evelien van; Faber, Hubert T.; Kunst, Dirk

doi:10.5152/iao.2017.2788

Cited by 4 publications

(10 citation statements)

References 11 publications

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“…In most reported cases of EBV-associated FNP with AOM, clinical symptoms suggesting IM were observed. 1,3 The two cases reported in this study also showed relative lymphocytosis with atypical lymphocytes. This is the first report to assess the EBV DNA level in blood samples collected from patients with EBV-associated FNP with AOM.…”

Section: Facial Nerve Palsy With Acute Otitis Media Associated With Eb Virus Infectionsupporting

confidence: 53%

Facial nerve palsy with acute otitis media associated with EB virus infection

Yamaguchi

Suzuki

Morita

et al. 2021

Pediatrics International

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Section: Facial Nerve Palsy With Acute Otitis Media Associated With Eb Virus Infectionsupporting

confidence: 53%

Facial nerve palsy with acute otitis media associated with EB virus infection

Yamaguchi

Suzuki

Morita

et al. 2021

Pediatrics International

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“…FNP with IM is rare in children, and although well‐recognised, the pathogenesis remains uncertain . Vogelnik et al .…”

Section: Discussionmentioning

confidence: 99%

“…Nonetheless, the finding of FNP in a child should prompt consideration of potential triggers, including Bell's palsy, Lyme disease (in appropriate geographic context), herpes simplex virus, varicella‐zoster virus and EBV (Table demonstrates aetiologies of FNP in childhood). In particular, when we see FNP with splenomegaly, we must consider IM, leukaemia/lymphoma and Heerfordt syndrome (sarcoidosis) . In fact, Smith et al .…”

Section: Discussionmentioning

confidence: 99%

“…FNP with IM is rare in children, and although well-recognised, the pathogenesis remains uncertain. [1][2][3] Vogelnik et al reported five patients with EBV-associated FNP due to AOM. 2,3 Although no consensus has been reached regarding the ability of EBV to directly infect the middle ear cavity or introduce secondary bacterial AOM, we assert that EBV-associated FNP due to AOM might be more common than previously thought.…”

Section: Key Pointsmentioning

confidence: 99%

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Facial nerve palsy with splenomegaly

Yokoyama

Takemura

Kuroda

et al. 2019

J Paediatrics Child Health

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A 12-month-old boy presented to our hospital with <24-h history of high-grade fevers and asymmetrical facial expression (day 1). This occurred on the background of a 5-day period of low-grade fevers and coryza.Physical examination showed peripheral facial nerve palsy (FNP) and acute otitis media (AOM) in the right ear (Fig. 1). He had no protruding auricle, pharyngitis, cervical lymphadenopathy, erythema, abdominal masses or abnormality of other nerves. Computed tomography of the head showed fluid accumulation in bilateral mastoid antra. White blood cell count was 13,700/μL (neutrophils 25.5%, lymphocytes 61.9%, monocytes 12.3%, basophils 0.3%) and C-reactive protein level was 10.81 mg/dL. The number of cells in cerebrospinal fluid (CSF) was 10/μL (mononuclear cells 10/μL, polymorphonuclear cells 0/μL), protein concentration was 13 g/dL, glucose level was 69 mg/dL. No bacteria were detected from blood or CSF cultures.We diagnosed FNP due to otomastoiditis and started the patient on cefotaxime (180 mg/kg/day), prednisolone (2.0 mg/kg/day) and acyclovir (45 mg/kg/day).FNP improved and fever resolved on day 3. The patient still had no pharyngitis, cervical lymphadenopathy or systemic erythema. However, the same day, we palpated an elastic, firm, smooth and painless mass in the left upper quadrant of the abdomen. We therefore conducted ultrasonography, revealing mild splenomegaly. In addition, white blood cell count increased to 20,800/μL, while C-reactive protein level decreased to 1.2 mg/dL. Atypical lymphocytes were seen in blood smears (12%). CD4/CD8 ratio was decreased to 0.4. We excluded the possibility of leukaemia or lymphoma by flowcytometry. These findings were most consistent with infectious mononucleosis (IM).

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“…У 7 больных мастоидит сочетался с отогенным менингитом, у 2 больных мастоидит протекал на фоне острого лимфобластного лейкоза, у 1 больного -на фоне болезни Виллебрандта, в 4 случаях отмечалась нейропатия лицевого нерва, у 9 пациентов мастоидит был двусторонним. В нашей практике встретились и атипичные формы болезни: мастоидит Муре, Бецольда, а также 2 случая петрозита [9][10][11].…”

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Analysis of Causes of Developing Complicated Forms of Acute Otitis Media in Children

Красножен

Andreeva

Mamleev

et al. 2018

Ross. vestn. perinatol. pediatr.

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The complicated course of acute otitis media in children not vaccinated against Streptococcus pneumoniae is progressively increasing. Up to 95% of children suffer at least one episode of acute otitis media during the first 7 years of life. Complications of this disease become a heavy burden for both patients, often leading to disability, and healthcare in general. The errors in antibiotic therapy of acute otitis media at the outpatient stage continue to be a serious problem. We present an analysis of the complications of acute otitis media in children and demonstrate the ways of solving this difficult problem.

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Surgical Treatment for Epstein-Barr Virus Otomastoiditis Complicated by Facial Nerve Paralysis: A Case Report of Two Young Brothers and Review of Literature

Cited by 4 publications

References 11 publications

Facial nerve palsy with acute otitis media associated with EB virus infection

Facial nerve palsy with acute otitis media associated with EB virus infection

Facial nerve palsy with splenomegaly

Analysis of Causes of Developing Complicated Forms of Acute Otitis Media in Children

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