Lymphocytic hypophysitis and headache in pregnancy

Biswas, Manoj; Thackare, H.; Jones, Margaret; Bowen-Simpkins, P

doi:10.1111/j.1471-0528.2002.01158.x

Cited by 13 publications

(6 citation statements)

References 12 publications

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“…Our patient had no subjective symptoms of sellar compression, such as headache, vomiting and visual disturbances, throughout her perinatal period. During pregnancy, there are many causes of headache, including tension headaches, migraine and pre‐eclampsia . Diagnosis of LAH is classically difficult; it can be easily mistaken for a pituitary adenoma; therefore, definitive diagnosis of LAH is pathological following surgery .…”

Section: Discussionmentioning

confidence: 99%

Post‐partum hypoglycemia and hypothermia as first manifestations of lymphocytic adenohypophysitis: A case report

Koyama

Okuno

Naoi

et al. 2016

J of Obstet and Gynaecol

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Lymphocytic adenohypophysitis is a very rare autoimmune disease characterized by an anterior pituitary infiltration of lymphocytes that cause various symptoms, such as headache, visual disturbance, and hypopituitarism. Lymphocytic adenohypophysitis is more common in women and has a remarkable association with the perinatal period. Recently, we experienced a case of lymphocytic adenohypophysitis shortly after delivery. A 37-year-old primiparous woman delivered her baby at 38 weeks' gestation. The next morning, she presented symptoms of hypoglycemia and hypothermia. Blood testing revealed hypoadrenalism and hypothyroidism. Pituitary magnetic resonance imaging showed characteristic findings consistent with lymphocytic adenohypophysitis. We immediately initiated medication with steroids and levothyroxine. Currently, her pituitary size has normalized and its function has fully recovered. Physical stress resulting from labor and delivery may unmask subclinical lymphocytic adenohypophysitis. Practitioners should keep in mind the possibility of lymphocytic adenohypophysitis in any pregnant women with symptoms of hypoglycemia and hypothermia after delivery.

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Section: Discussionmentioning

confidence: 99%

Post‐partum hypoglycemia and hypothermia as first manifestations of lymphocytic adenohypophysitis: A case report

Koyama

Okuno

Naoi

et al. 2016

J of Obstet and Gynaecol

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“…The clinical signs of a mass effect in the pituitary fossa (headache and visual disturbance) are more common than hormonal imbalance. However, 40% of cases have hyperprolactinaemia, 60% anterior pituitary insufficiency, up to 20% diabetes insipidus (as a result of neurohypophyseal involvement), and up to 20% other autoimmune conditions 10 . Intracranial pressure is rarely raised, and hence convulsions are an unusual presentation 11 .…”

Section: Discussionmentioning

confidence: 99%

Seizures and the Pituitary Gland during Pregnancy

2004

Anaesth Intensive Care

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“…This inverse relationship might implicate a fall in oxytocin levels in progression of prostate cancer. Within the prostate, oxytocin has been shown to affect gland growth both directly and via its interaction with androgen metabolism, and oxytocin concentrations are positively correlated with androgens[ 20 , 80 ]. Indeed, while in the absence of androgens oxytocin had no effect on prostate cancer cell lines (LNCaP and PC-3), in the presence of testosterone low oxytocin doses stimulated proliferation of PC-3 cells[ 81 ], supporting the notion that changes in levels of oxytocin in the prostate in aging and cancer may promote prostate epithelial cell proliferation.…”

Section: Oxytocin In Cancermentioning

confidence: 99%

Oxytocin and cancer: An emerging link

Lerman¹,

Harricharran²,

Ogunwobi³

2018

WJCO

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The neuropeptide hormone oxytocin, which is released from the posterior pituitary gland, is involved in a number of physiological processes. Understanding of its effects is gradually increasing due to new research in this area. While mostly recognized as a reproductive system hormone, oxytocin also regulates other organ systems such as the brain and cardiovascular system. Recently, research has focused on unraveling its involvement in cancer, and emerging evidence suggests a potential role for oxytocin as a cancer biomarker. This review summarizes observations linking oxytocin and cancer, with a special emphasis on prostate cancer, where it may promote cell proliferation. Research suggests that oxytocin effects may depend on cell type, concentration of the hormone, its interactions with other hormones in the microenvironment, and the precise localization of its receptor on the cell membrane. Future research is needed to further elucidate the involvement of oxytocin in cancer, and whether it could be a clinical cancer biomarker or therapeutic target.

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Lymphocytic hypophysitis and headache in pregnancy

Cited by 13 publications

References 12 publications

Post‐partum hypoglycemia and hypothermia as first manifestations of lymphocytic adenohypophysitis: A case report

Post‐partum hypoglycemia and hypothermia as first manifestations of lymphocytic adenohypophysitis: A case report

Seizures and the Pituitary Gland during Pregnancy

Oxytocin and cancer: An emerging link

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