Lymphoepithelioma-like carcinoma of the lung: a rare case report and review of the literature

Fırıncıoğluları, Ali; Özyürek, Berna Akıncı; Erdoğan, Yurdanurr; Incekara, Funda; Yılmaz, Emre; Özaydın, Hatice Esra

doi:10.5578/tt.69322

Cited by 2 publications

(1 citation statement)

References 9 publications

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“…The latest literature search was performed in March 2021. Having carefully evaluated the extracted studies, we selected 42 relevant studies and the EBV status in LCs was summarized in Table 2 [ 12 , 36 , 37 , 38 , 39 , 40 , 41 , 42 , 43 , 44 , 45 , 46 , 47 , 48 , 49 , 50 , 51 , 52 , 53 , 54 , 55 , 56 , 57 , 58 , 59 , 60 , 61 , 62 , 63 , 64 , 65 , 66 , 67 , 68 , 69 , 70 , 71 , 72 , 73 , 74 , 75 , 76 ].…”

Section: Presence Of Ebv In Lung Cancersmentioning

confidence: 99%

Pathogenic Role of Epstein–Barr Virus in Lung Cancers

Becnel

Abdelghani

Nanbo

et al. 2021

Viruses

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Human oncogenic viruses account for at least 12% of total cancer cases worldwide. Epstein–Barr virus (EBV) is the first identified human oncogenic virus and it alone causes ~200,000 cancer cases and ~1.8% of total cancer-related death annually. Over the past 40 years, increasing lines of evidence have supported a causal link between EBV infection and a subgroup of lung cancers (LCs). In this article, we review the current understanding of the EBV-LC association and the etiological role of EBV in lung carcinogenesis. We also discuss the clinical impact of the knowledge gained from previous research, challenges, and future directions in this field. Given the high clinical relevance of EBV-LC association, there is an urgent need for further investigation on this topic.

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Section: Presence Of Ebv In Lung Cancersmentioning

confidence: 99%

Pathogenic Role of Epstein–Barr Virus in Lung Cancers

Becnel

Abdelghani

Nanbo

et al. 2021

Viruses

View full text Add to dashboard Cite

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Lymphoepithelioma-Like Carcinoma of the Lung Associated With Epstein-Barr Virus in a Caucasian Patient: A Case Report

Lampridis¹,

Gkikas²,

Pisciella³

et al. 2022

Cureus

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Primary pulmonary lymphoepithelioma-like carcinoma (LELC) is a rare tumour that is histologically identical to the lymphoepithelioma originally described in the nasopharynx. It mostly occurs in endemic regions in Asia, where it is associated with Epstein-Barr virus (EBV) infection. The incidence of primary pulmonary LELC is even lower in the Western population, in which an association with EBV is not typically observed. In this report, we present the case of a 78-year-old Caucasian woman who was diagnosed with EBV-positive pulmonary LELC following lingulectomy and histopathological examination of the tumour. Metastasis from the nasopharynx was excluded clinically and radiologically. Due to the absence of regional lymph node involvement, the patient did not receive adjuvant therapy. She remained free of disease at the one-year follow-up. Reporting cases of primary pulmonary LELC in non-Asian patients can help to elucidate the association with EBV infection and its potential implications for diagnosis, treatment, and follow-up.

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Lymphoepithelioma-like carcinoma of the lung: a rare case report and review of the literature

Cited by 2 publications

References 9 publications

Pathogenic Role of Epstein–Barr Virus in Lung Cancers

Pathogenic Role of Epstein–Barr Virus in Lung Cancers

Lymphoepithelioma-Like Carcinoma of the Lung Associated With Epstein-Barr Virus in a Caucasian Patient: A Case Report

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