Lymphoma presenting as a parotid tumour: a population-based study of diagnosis, treatment and outcome on behalf of the Scotland and Newcastle Lymphoma Group

US of the Major Salivary Glands: Anatomy and Spatial Relationships, Pathologic Conditions, and Pitfalls

“…However, primary involvement of salivary glands is rare; they are usually one of the sites of systemic disease. Clinically, salivary lymphomas most often manifest as a painless, progressive swelling (107,108). They are usually associated with autoimmune disease, most often with Sjö gren syndrome, sometimes also with rheumatoid arthritis (62)(63)(64)109).…”

Isolated B-cell non-Hodgkin's lymphoma of the parotid gland presenting as an ulcerating facial mass and sepsis during an acute medical take

“…Within this series, the average age of presentation was 69 years with a male-to-female ratio of 1 : 1.3 and the majority of patients had stage IE (stage IE is disease outside the lymph system in one organ or area) at the time of presentation. The prognosis was favourable with a median survival of 90 months 12. With respect to our case using the International Prognostic Index, owing to our patient's poor general health, his 5 -year survival is calculated at 51% at the time of diagnosis.…”

“…From a search of the literature, only one such case has recently been reported 10. There is also a series of 12 cases identified during a 12 -year period presenting to a tertiary centre11 and a series of 136 cases identified from the Scotland and Newcastle Lymphoma Registry that presented between 1979 and 1999 12. Within the latter study, non-Hodgkin's lymphoma presenting in the parotid gland represented 1.5% of 8499 cases of non-Hodgkin's lymphoma within the registry.…”

Mantle Cell Lymphoma Presenting as Mikulicz Syndrome

“…But, lymphoma presenting as a Mikulicz syndrome with involvement of both salivary and lacrimal glands is very rare. From the Scotland and Newcastle Lymphoma Registry, 12 which is a prospectively collected population-based register of consecutive cases of lymphoma since 1979, 136 patients were identified with a biopsy-proven lymphoma in the parotid gland as the first presentation of their disease. One hundred twenty-eight had non-Hodgkin lymphoma (representing 1.5% of the 8499 nonHodgkin lymphomas in the registry) and 8 had Hodgkin disease (0.3% of the 2716 cases registered).…”