Lymphosarcoma in Indian Buffaloes

Singh, Charan

doi:10.1159/000391264

Cited by 3 publications

(6 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The lesions are characterized by floccules (miliary nodules), nodules, and papillae of continuous growth and velvety appearance on the parietal and visceral surfaces of the serosal membranes of organs. The involvement of lymph nodes occurs through mild tumefaction with varying degrees of swelling [ 3 , 4 ].…”

Section: Introductionmentioning

confidence: 99%

Multicentric lymphoma in buffaloes in the Amazon region, Brazil

et al. 2016

View full text Add to dashboard Cite

BackgroundThe presence of lymphoma in buffaloes was first reported in India in the 1960s. The disease is similar to Enzootic Bovine Leucosis (EBL) caused by Bovine leukemia virus (BLV) in cattle; however, according to our results and those of other studies, the etiology of these lymphomas in buffalo do not appear to be associated with BLV. The objectives of this study are to describe four cases of the disease in buffaloes belonging to the same herd in the Amazon region of Brazil and to perform a clinical-anatomopathological, immunohistochemical, and etiological study of the lymphomas.ResultsOver a period of ten years, four buffaloes were observed presenting progressive weight loss, swelling of peripheral lymph nodes, and nodules in the subcutaneous tissue. Upon necropsy, whitish-colored tumor masses were observed in the form of nodules in the subcutaneous tissue, along with miliary nodules on the serosal surfaces of abdominal and thoracic organs and tumors in lymph nodes and other organs. Neoplastic lymphocyte proliferation was observed through histopathology. An immunohistochemical study revealed that the neoplasias were formed by proliferation of predominantly B lymphocytes. The presence of BLV genome was not detected in the lymphomas when using the real-time PCR technique, nor was it detected through immunohistochemical staining using monoclonal antibodies against two viral proteins. Bovine herpesvirus 6 was not detected in the tumors. However, Bovine immunodeficiency virus (BIV) was detected in samples of lymphoma and in the lymph nodes and kidneys of one of the animals.ConclusionsThe occurrence of lymphoma in buffaloes is reported for the first time in Brazil and is characterized by B-cell multicentric lymphoma. The etiology of the disease does not appear to be associated with BLV; however, the detection of BIV in samples of lymphoma from one sick animal deserves further study, considering the oncogenic potential of this virus.Electronic supplementary materialThe online version of this article (doi:10.1186/s12917-016-0845-y) contains supplementary material, which is available to authorized users.

show abstract

Section: Introductionmentioning

confidence: 99%

Multicentric lymphoma in buffaloes in the Amazon region, Brazil

et al. 2016

View full text Add to dashboard Cite

show abstract

“…More animals need to be examined in other breeds to provide a reliable estimate of the breed incidence of LS in India. The affected Malvi bullock originated from the upper central part of India, the same general area in northern India (Uttar Pradesh), which was the basis of the report describing a high incidence of LS in buffaloes (17.8%) [14]. This could suggest that LS is more prevalent in north than in south India.…”

Section: Discussionmentioning

confidence: 97%

“…in Scotland |4]. In India, the incidence of LS in cattle is not yet known, excepting for a survey of LS in Indian buf faloes from abattoirs [14], and a solitary case report in a new-born calf from a healthy cow [13]. To provide base-line information regarding the incidence of LS and other malignant diseases, including carcinoma of the horn and eye in Indian Zebu cattle, a survey was undertaken at a local abattoir in Bombay which slaughters about 5,000 cattle per month.…”

mentioning

confidence: 99%

Lymphosarcoma in Indian Zebu Cattle

Naik¹,

Dabholkar²,

Randelia³

1971

Oncology

View full text Add to dashboard Cite

The incidence of bovine lymphosarcoma was studied in 79,492 male adult Indian cattle of 7 different breeds and crossbreeds from one abattoir in Bombay. One of 23,066 Malvi animals, a bullock, was detected with multicentric LS with symmetrically enlarged lymph nodes and spleen. Examination of blood, lymph nodes and spleen confirmed the leukotic condition of the animal. The incidence of bovine LS in India and Western countries is compared, and the interrelationship between leukemia in different species of domestic animals and man is discussed. The need for further epidemiological studies of leukemia in domestic pets and food producing animals in India is suggested.

show abstract

“…There were serous exudation and hemorrhage. Lymphosarcoma particularly affecting the serous surface of the uterus was described by Singh [89] and Singh et al [90]. Lymphofollicular aggregates were evident on the serosal surface.…”

Section: Pathology Of Uterusmentioning

confidence: 91%

“…In adenoma, a large nodule surrounded by dense capsule was noticed in the endometrium. In the centre of the nodule, connective and Singh [88]. Microscopically, the tumour cells were rounded or satellite in appearance with infrequent mitotic figures.…”

Section: Pathology Of Uterusmentioning

confidence: 97%