Lytic bacteriophages reduce<i><i>Escherichia coli</i></i>O157

Ferguson, Sean; Roberts, Cheryl; Handy, Eric T.; Sharma, Manan

doi:10.4161/bact.24323

Cited by 68 publications

(30 citation statements)

References 20 publications

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“…Aerosols are solid or liquid suspensions in the air and their particle size range is 0.001-100 μm [8]. Once formed, aerosols, including those containing viruses, can rapidly spread to a larger area with the assistance of the wind [9]. However, little is known about the transmission and infection of the novel S-O 2009 IV via aerosols, and there is still some debate about airborne infection of this virus [7,8,10,11].…”

Section: Introductionmentioning

confidence: 99%

Airborne spread and infection of a novel swine-origin influenza A (H1N1) virus

Zhang

et al. 2013

Virol J

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BackgroundThe novel swine-origin influenza A (H1N1) virus (S-O 2009 IV) can cause respiratory infectious diseases in humans and pigs, but there are few studies investigating the airborne spread of the virus. In January 2011, a swine-origin H1N1 epidemic emerged in eastern China that rapidly spread to neighboring farms, likely by aerosols carried by the wind.MethodsIn this study, quantitative reverse transcription polymerase chain reaction (RT-PCR) was used to detect viruses in air samples from pig farms. Based on two aerosol infection models (Pig and guinea pig), we evaluated aerosol transmission and infection of the novel S-O 2009 IV isolate.ResultsThree novel S-O 2009 IV were isolated from the diseased pig. The positive rate and viral loads of air samples were 26.1% and 3.14-5.72 log10copies/m3 air, respectively. In both pig and guinea pig infection models, the isolate (A/swine/Shandong/07/2011) was capable of forming aerosols and infected experimental animals at a range of 2.0-4.2 m by aerosols, but aerosol route was less efficient than direct contact.ConclusionsThe results indicated that S-O 2009 IV is able to be aerosolized by infected animals and to be transmitted to susceptible animals by airborne routes.

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Section: Introductionmentioning

confidence: 99%

Airborne spread and infection of a novel swine-origin influenza A (H1N1) virus

Zhang

et al. 2013

Virol J

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“…When combined with nisin, a phage treatment reduced L. monocytogenes on apples and melons by 2.3 and 5.7 log cfu, respectively . In a study of lytic bacteriophages, E. coli O157:H7-inoculated lettuce was treated by immersion or spray application (Ferguson et al, 2013). The authors concluded that both methods provided protection from E. coli O157:H7 contamination on lettuce, but spray application of lytic bacteriophages to lettuce was more effective in immediately reducing pathogen populations on fresh-cut lettuce.…”

Section: Technology For Reduction Of Human Pathogens In Fresh Producementioning

confidence: 99%

Salmonella and Tomatoes

Bartz¹,

Marvasi²,

Teplitski³

2014

The Produce Contamination Problem

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Academic Press is an imprint of ElsevierNo part of this publication may be reproduced, stored in a retrieval system or transmitted in any form or by any means electronic, mechanical, photocopying, recording or otherwise without the prior written permission of the publisher Permissions may be sought directly from Elsevier's Science & Technology Rights Department in Oxford, UK: phone (+44) (0) 1865 843830; fax (+44) (0) 1865 853333; email: permissions@elsevier.com. Alternatively you can submit your request online by visiting the Elsevier web site at http://elsevier.com/locate/permissions, and selecting Obtaining permission to use Elsevier material NoticeNo responsibility is assumed by the publisher for any injury and/or damage to persons or property as a matter of products liability, negligence or otherwise, or from any use or operation of any methods, products, instructions or ideas contained in the material herein. Because of rapid advances in the medical sciences, in particular, independent verification of diagnoses and drug dosages should be made British Library Cataloguing in Publication DataA catalogue record for this book is available from the British Library Library of Congress Cataloging-in-Publication DataA catalog record for this book is available from the Library of Congress Printed and bound in the United States PART 3 CONTAMINATION AVOIDANCE PRE AND POSTHARVEST CHAPTER 15 Produce Contamination Issues in Mexico and CHAPTER 16 Regulatory Issues in Europe RegardingFresh PART 4 TECHNOLOGY FOR REDUCTION OF HUMAN PATHOGENS IN FRESH PRODUCE PrefaceThe premise of the book is that once human pathogen contamination of fresh produce occurs, it is extremely difficult to reduce pathogen levels sufficiently with currently available technologies based on washing with sanitizing agents to assure microbiological safety. Outbreaks since the first edition of this book was published have been attributed to consumption of fresh commodities including but not limited to cantaloupes, mangoes, tomatoes, seed sprouts, and salad greens. Globally extensive research, published in thousands of scientific papers and documents, has focused on the microbiological safety of fresh produce. Disinfection methods whether conventional or based on new innovative technology fail to reduce pathogen loads on produce to levels consistent with product safety.Produce decontamination methods are surprisingly similar in the level of reductions in pathogens they achieve. Methods that are effective, irradiation and high pressure, are either not accepted by a large segment of consumers or not practical for all types of fresh produce. The intrinsic interaction of microbes with plant tissues, internalization, biofilm formation, and association with inaccessible sites contributes to the insufficient reduction in microbial populations to assure product safety. The key to improving the microbial safety of fresh products is the development of wiser strategies to avoid human pathogen contamination of the products rather than focusing on disinfect...

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“…In this application, the phage is applied as a liquid preparation to the surfaces of the food product immediately prior to packaging. In a study of lytic bacteriophages, E. coli O157:H7-inoculated lettuce was treated by immersion or spray application (Ferguson et al, 2013). The specific and most optimal means of usage are still being determined, e.g.…”

Section: Biological Controlsmentioning

confidence: 99%