With rapidly developing communication and autonomous-driving technology, traffic flow on road networks will change from homogeneous human-driven vehicle (HDV) traffic flow to heterogeneous mixed traffic flow (MTF) comprising HDVs, autonomous vehicles (AVs), and connective-and-autonomous vehicles (CAVs). To understand the changes in the MTF of transportation engineering, we investigated the reserved capacity (RC) and right-of-way (ROW) reallocation policy that should be utilized under MTF scenarios. We established an MTF-based theoretical model to calculate the expressway segment capacity, theoretically analyzed the influence of the market penetration rate (MPR) on capacity and validated the model through numerical analysis. The results showed that the MPR of AVs and CAVs can enhance the MTF RC that is within 0–200% and that the platooning rate of CAVs positively influences the MTF RC. CAV popularization does not necessarily lead to a rapid increase in the transportation system efficiency when the MPR is <40% but significantly improves the efficiency of existing urban transportation facilities. When the MPR is >40%, the greatest enhancement is 4800 pcu/h/lane in terms of RC. A ROW reallocation policy that equips CAV-dedicated lanes according to the MPR of AVs and CAVs can enhance the capacity of expressway systems by 500 pcu/h/lane in terms of RC.