Machine Learning‐Driven Biomaterials Evolution

Suwardi, Ady; Wang, Fuke; Ke-min, Xue; Han, Ming‐Yong; Teo, Peili; Wang, Pei; Wang, Shijie; Liu, Ye; Ye, Enyi; Zibiao, Li; Loh, Xian Jun

doi:10.1002/adma.202102703

Cited by 113 publications

(76 citation statements)

References 290 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…It is possible to estimate the potential biocompatibility of 2D materials using machine-learning-driven simulation and calculation on biomaterials' design and hazard reduction. [1151][1152][1153][1154][1155] What matters is whether or not 2D materials can be shown to be safe for humans to use in vivo so that the ambiguity in the biocompatibility of 2D materials may be clarified. [475] 3) Making 2D materials-based wearable energy harvesters more efficient and effective.…”

Section: Discussionmentioning

confidence: 99%

2D Materials for Wearable Energy Harvesting

Lee

2022

Adv Materials Technologies

View full text Add to dashboard Cite

theoretical investigation into the effect of surface tension component ratios between the polar and dispersion components of applied solvents and 2D materials (Figure 3b). [523] The results indicated that a solvent suited for certain 2D materials LPE should have surface tension component ratios similar to the 2D materials. [523] However, direct exfoliation using sonication and Figure 3. Top-down approaches in 2D materials preparation. a) Schematically illustration of ultrasonic-assisted exfoliation. Reproduced with permission. [524] Copyright 2013, American Association for the Advancement of Science. b) Top and middle rows: dispersibility of graphene and MoS 2 as a function of total surface tension and polar to dispersive ratio. Bottom row showing the thickness histogram of graphene and MoS 2 exfoliated using solvents with the optimal surface tension and polar to dispersive component ratio. Reproduced with permission. [523] Copyright 2015, American Chemical Society. c) Detailed schematic of cathodic exfoliation (top) and anodic exfoliation (bottom) of graphene from graphite. Reproduced with permission. [1184] Copyright 2015, Elsevier. d) DFT calculation results of ion-intercalation exfoliation of graphite into graphene using SO 4 2− ion (bottom left), Li ion (top right) and K ion (bottom right). Reproduced under terms of the CC-BY license. [565] Copyright 2017, The Authors, published by the Royal Society of Chemistry. e) Left: SEM image (top) and AFM image (bottom) of a typical graphene obtained by ion-intercalated exfoliation. Right: Lateral size (top) and thickness (bottom) distribution of graphene through ion-intercalation exfoliation. Reproduced with permission.

show abstract

Section: Discussionmentioning

confidence: 99%

2D Materials for Wearable Energy Harvesting

Lee

2022

Adv Materials Technologies

View full text Add to dashboard Cite

show abstract

“…Moreover, it is estimated that, in the near future, personalized prosthetic biomaterials could be developed and improved, based on the important acquisition of data at the individual level (biomarkers), including at the salivary level [ 15 , 137 ]. Furthermore, the application of machine learning in material science will allow the acceleration of development in biomaterial manufacturing [ 138 ].…”

Section: Definitive Prosthetic Materials Used For Obtaining Oral Impl...mentioning

confidence: 99%

Prosthetic Materials Used for Implant-Supported Restorations and Their Biochemical Oral Interactions: A Narrative Review

et al. 2022

View full text Add to dashboard Cite

The purpose of this study is to outline relevant elements regarding the biochemical interactions between prosthetic materials used for obtaining implant-supported restorations and the oral environment. Implant-supported prostheses have seen unprecedented development in recent years, benefiting from the emergence of both new prosthetic materials (with increased biocompatibility and very good mechanical behavior), and computerized manufacturing technologies, which offer predictability, accuracy, and reproducibility. On the other hand, the quality of conventional materials for obtaining implant-supported prostheses is acknowledged, as they have already proven their clinical performance. The properties of PMMA (poly (methyl methacrylate))—which is a representative interim material frequently used in prosthodontics—and of PEEK (polyether ether ketone)—a biomaterial which is placed on the border between interim and final prosthetic use—are highlighted in order to illustrate the complex way these materials interact with the oral environment. In regard to definitive prosthetic materials used for obtaining implant-supported prostheses, emphasis is placed on zirconia-based ceramics. Zirconia exhibits several distinctive advantages (excellent aesthetics, good mechanical behavior, biocompatibility), through which its clinical applicability has become increasingly wide. Zirconia’s interaction with the oral environment (fibroblasts, osteoblasts, dental pulp cells, macrophages) is presented in a relevant synthesis, thus revealing its good biocompatibility.

show abstract

“…Polymer development is largely based on an iterative process which requires significant resources, time and intuition. Increasingly, the field is developing machine-learning tools to predict properties of polymers in-silico ( 59 ). This data-driven approach may enable rational polymer design based on the required function in the tissue type the polymer interacts with.…”

Section: Translational Hurdlesmentioning

confidence: 99%

Polymeric biomaterials in the treatment of posterior segment diseases

et al. 2022

View full text Add to dashboard Cite

Polymeric biomaterials are biological or synthetic substances which can be engineered to interact with biological systems for the diagnosis or treatment of diseases. These biomaterials have immense potential for treating eyes diseases, particularly the retina—a site of many inherited and acquired diseases. Polymeric biomaterials can be engineered to function both as an endotamponade agent and to prevent intraocular scarring in retinal detachment repair surgeries. They can also be designed as a drug delivery platform for treatment of retinal diseases. Finally, they can be used as scaffolds for cellular products and provide non-viral gene delivery solutions to the retina. This perspective article explains the role of polymeric biomaterials in the treatment of retinal conditions by highlighting recent advances being translated to clinical practice. The article will also identify potential hurdles to clinical translation as future research directions in the field.

show abstract

Machine Learning‐Driven Biomaterials Evolution

Cited by 113 publications

References 290 publications

2D Materials for Wearable Energy Harvesting

2D Materials for Wearable Energy Harvesting

Prosthetic Materials Used for Implant-Supported Restorations and Their Biochemical Oral Interactions: A Narrative Review

Polymeric biomaterials in the treatment of posterior segment diseases

Contact Info

Product

Resources

About