Macroscopic Evaluation of Gastric Specimens After Laparoscopic Sleeve Gastrectomy—an Optimum Screening Test for Incidental Pathologies?

Różańska-Walędziak, Anna; Janik, Michał; Paśnik, Krzysztof; Kowalewski, Piotr

doi:10.1007/s11695-018-3485-4

Cited by 9 publications

(5 citation statements)

References 19 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Generally, pre-malignant lesions identified in LSG specimens across 11 studies varied from 4.1 to 33.2% [10,18,[36][37][38][39][40][41][42][43][44]. However, across these 11 abovementioned studies, there was zero actual malignancy reported, despite that these studies were undertaken in a wide variety of geographical areas worldwide with different risk of gastric cancers.…”

Section: Discussionmentioning

confidence: 99%

“…Thus, even with our 7.5% pre-malignant lesions identified in LSG specimens, and with the huge number of LSG procedures undertaken worldwide, such current lack of the evidence base renders us unable to extrapolate in any way the potential number of patients with pre-malignant lesions that would actually turn malignant or whether such numbers would be high and alarming or otherwise. Hence, there exists much debate regarding the role of routine histopathological examination of LSG specimens [10,18,[36][37][38][39][40][41][42][43][44], and some authors have suggested that histopathological examination of LSG specimens is to be done when intraoperative macroscopic pathology is observed [10,18,43]. Future research would benefit from addressing these points.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Compared to What? Is BMI Associated with Histopathological Changes in Laparoscopic Sleeve Gastrectomy Specimens?

2019

View full text Add to dashboard Cite

Background Obesity is a risk for many different cancers. Laparoscopic sleeve gastrectomy (LSG) is common, and benign or premalignant histopathology types are reported in the removed gastric specimens. We assessed whether higher BMI was associated with certain benign or pre-malignant histopathological changes. Method Retrospective chart review of all primary LSG patients (N = 1555). Demographic, clinical, and LSG histopathology data were retrieved. BMI of patients with specific benign or pre-malignant conditions in their gastric specimens was compared with the BMI of the rest of the patients with abnormal histopathology specimens and also compared with the BMI of patients with normal control specimens.Results Females comprised 70% of the patients. Mean BMI were 46.3 (females) and 48 (males). Normal LSG specimens comprised 52%. Most common abnormal histopathologies were chronic inactive gastritis (33%), chronic active gastritis (6.8%), follicular gastritis (2.7%), lymphoid aggregates (2.2%), intestinal metaplasia (1.4%) and GIST (0.7%). After controlling for confounders (age, gender, H. pylori, diabetes mellitus type 2, hypertension), no significant association was observed between the BMI of patients with specific benign or pre-malignant histopathology compared with the BMI of the rest of the patients with abnormal histopathologies and compared to the BMI of patients with normal histopathologies. Conclusion When confounders were taken into account, there appeared no significant associations between the BMI of patients with specific benign or pre-malignant histopathology compared with the BMI of the rest of the patients with abnormal histopathologies and compared to the BMI of patients with normal histopathologies of their gastric specimens. There was a very weak correlation between BMI and other covariates.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Compared to What? Is BMI Associated with Histopathological Changes in Laparoscopic Sleeve Gastrectomy Specimens?

2019

View full text Add to dashboard Cite

show abstract

“…Bir çalışmada, makroskopik değerlendirme mikroskobik değerlendirme ile karşılaştırılmış ve olguların %75'inde makroskopik değerlendirmenin patolojileri ortaya çıkardığını ve %99,1 gibi yüksek bir negatif tahmin değeri sunduğunu belirtmişlerdir (23) .…”

Section: Discussionunclassified

“…Genel olarak, LSG'de tanımlanan pre-malign lezyonlar 11 çalışmada %4,1 ila 33,2 arasında değişmiştir (8,18,23) . Bununla birlikte, yukarıda söz edilen bu 11 çalışmada, sıfır gerçek malignite olduğu bildirilmiştir.…”

Section: Discussionunclassified

See 1 more Smart Citation

Is Routine Histopathological Evaluation of Resection Material Necessary After Sleeve Gastrectomy?

Kizilkaya¹,

Bozkurt²

2021

IKSST

View full text Add to dashboard Cite

INTRODUCTION: Considering the recent publications on incidental findings after laparoscopic sleeve gastrectomy (LSG), various studies have been conducted to analyze the benefit of examining bariatric samples. In our study, we discussed the necessity of microscopic evaluation in the light of the literature by comparing the macroscopic examination notes of the resection material removed after LSG with the histopathological examination results of the same specimens. METHODS: The data of patients who underwent laparoscopic sleeve gastrectomy as a bariatric procedure due to obesity between 2018-2020 were retrospectively analyzed. Patients' gender, age, surgical procedure, body mass indexes(vki), endoscopic biopsy examination results performed before surgery, postoperative surgeon's macroscopic examination records and postoperative pathology specimens’ histopathological examination results were recorded. RESULTS: 154 patients were included in the study. The average age of the patients was 35.35±9.42(19-60). There were 17 men and 137 women. The mean age of the male patients was 32.82±9.12(22-53). The mean age of the female patients was 35.67±8.57(19-60). The mean BMI of the patients included in the study was 45.48±5.12(40-59). Helicobacter pylori (HP) was detected in 42(27.2%) patients after the examination of the specimen. Chronic gastritis was detected in 108(70.1%) patients. Intestinal metaplasia was detected in 2(0.01%) patients. Gastrointestinal stromal tumor (GIST) was detected in 1 (0.006%) patient. DISCUSSION AND CONCLUSION: In the light of our study, it was seen that routine microscopic examination of resection material after LSG has no additional positive effect on the patient's health. Randomized controlled studies with sufficient sample size are needed.

show abstract

The Relationship Between Histopathologic Findings and Weight Loss in Laparoscopic Sleeve Gastrectomy

et al. 2019

View full text Add to dashboard Cite

Macroscopic Evaluation of Gastric Specimens After Laparoscopic Sleeve Gastrectomy—an Optimum Screening Test for Incidental Pathologies?

Cited by 9 publications

References 19 publications

Compared to What? Is BMI Associated with Histopathological Changes in Laparoscopic Sleeve Gastrectomy Specimens?

Compared to What? Is BMI Associated with Histopathological Changes in Laparoscopic Sleeve Gastrectomy Specimens?

Is Routine Histopathological Evaluation of Resection Material Necessary After Sleeve Gastrectomy?

The Relationship Between Histopathologic Findings and Weight Loss in Laparoscopic Sleeve Gastrectomy

Contact Info

Product

Resources

About