The Relationship Between Histopathologic Findings and Weight Loss in Laparoscopic Sleeve Gastrectomy

Erkinüresin, Taşkın; Demirci, Hakan; Çaycı, Hacı Murat; Erdoğdu, Umut Eren

doi:10.1007/s11695-019-04185-9

Cited by 10 publications

(8 citation statements)

References 14 publications

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“…Therefore, premalignant lesions such as IM, severe atrophic changes, or dysplasia in the VSG specimen should be an alarm for further endoscopic follow-ups. Previous serious review of histopathologic findings after VSG revealed the prevalence of IM to be between 0.3% and 9.9% of cases 8–10,18,23–28. In our study, IM was detected in 5.3% of all specimens after VSG.…”

Section: Discussionsupporting

confidence: 53%

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Association of Hypercholesterolemia With Gastric Intestinal Metaplasia, Findings After Sleeve Gastrectomy Pathology Review

Kermansaravi

Rezvani²,

Sadr

et al. 2022

Surgical Laparoscopy, Endoscopy &Amp; Percutaneous Techniques

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Background: We evaluated the relationship between comorbidities associated with obesity, body mass index (BMI), and development of intestinal metaplasia (IM) after vertical sleeve gastrectomy (VSG). Materials and Methods: All VSG specimens performed at an academic center between 2011 and 2018 were reviewed. All specimens underwent histopathologic assessment, while those with findings suspicious for IM underwent additional immunohistochemical work up. Baseline patient characteristics and demographic data were obtained from Iran National Obesity Surgery Database by retrospective review. Results: A total of 862 adult individuals underwent VSG during the study period and specimens were histopathologically examined. All patients had preoperative upper endoscopy. The most common histopathologic diagnosis was miscellaneous findings (57.8%) followed by no pathologic finding (36.7%). The minority of patients (5.5%) had IM. Although 40.5% of patients had positive Helicobacter pylori infection preoperatively, just 13.8% had still positive infection postoperatively. A significant association was found between IM and hypercholesterolemia (odds ratio: 1.95; 95% confidence interval: 1.1, 3.5). Conclusion: This study found a correlation between histopathologic changes in patients with IM and hypercholesterolemia. Prospective research studies are recommended to further examine this correlation.

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Section: Discussionsupporting

confidence: 53%

“…Previous serious review of histopathologic findings after VSG revealed the prevalence of IM to be between 0.3% and 9.9% of cases. [8][9][10]18,[23][24][25][26][27][28] In our study, IM was detected in 5.3% of all specimens after VSG.…”

Section: Discussionsupporting

confidence: 48%

Association of Hypercholesterolemia With Gastric Intestinal Metaplasia, Findings After Sleeve Gastrectomy Pathology Review

Kermansaravi

Rezvani²,

Sadr

et al. 2022

Surgical Laparoscopy, Endoscopy &Amp; Percutaneous Techniques

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“…Once again, in published studies, the rate of H. pylori infection varies from one country to another due to dietary habits, cultural factors, and differences in social and economic status [26]. For instance, in previously published studies, Demirbas et al [15] found the same rate of H. pylori infection as ours (27%), while Dogan et al [18], Erkinuresin et al [19], and Öner et al [20] reported that they found a higher rate of H. pylori infection (43,2%, 41,7%, and 64%, respectively). Contrary to these results, a lower prevalence of H. pylori infection was reported by Di Palma et al [16], and Canil et al [27] where they found the rate to be 3.2% and 2.4%, respectively.…”

Section: Discussionsupporting

confidence: 52%

“…Similar to our findings, Dogan et al [18] found active chronic gastritis in 35.05% of the cases, but in terms of chronic gastritis and intestinal metaplasia, they found a lower rate of 19.9% and 2.7% respectively. In another study, Erkinuresin et al [19] also revealed similar results. They found active chronic gastritis in 37.1% of the cases, but intestinal metaplasia was found only in 9.9% of the cases.…”

Section: Discussionmentioning

confidence: 53%

Histopathological findings on resected gastric specimens from obese patients undergoing laparoscopic sleeve gastrectomy

Mocian

Sorlea

Coroș

2023

Medicine and Pharmacy Reports

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Background and aims. This study aimed to investigate the relationship between baseline characteristics of obese patients and histopathological findings on resected gastric specimens resulted after laparoscopic sleeve gastrectomy. Methods. Seventy-seven patients undergoing laparoscopic sleeve gastrectomy in a university surgical department from Romania were included in the present study. Demographic data, preoperative Body Mass Index values, and their relationship with the histopathological findings of resected gastric specimens were statistically analyzed. Results. The mean age of patients included was 40.2 ± 11.05 years and the mean Body Mass Index was 43.5 ± 7.8 kg/m2; 71.4% of the patients were female. Active chronic gastritis was the most common gastric pathology (39%) encountered. Helicobacter pylori infection was present in 27.2% of the cases. Normal gastric histology was found in 33.7% of the specimens. A strong statistically significant association was noted between Helicobacter pylori infection and active chronic gastritis (p<0.0001). Similarly, a statistically significant association was observed between age, Body Mass Index, and intestinal metaplasia (p=0.005 and p=0.009 respectively). No malignancies were found. Conclusions. Our study results show that the incidence of active chronic gastritis and Helicobacter pylori infection is relatively high in obese patients. Considering this, we conclude that it is important to send the resected gastric specimens for histopathological analysis after laparoscopic sleeve gastrectomy.

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“…Previous studies that compared normal gastric histopathological findings with other histopathologies in terms of weight loss are unavailable. However, Erkinuresin et al [22] reported that younger patients who had low BMI and inactive gastritis and underwent LSG could achieve more successful weight loss results than the older ones. Globally, H. pylori infection is responsible for chronic bacterial infection, and most of the affected individuals are asymptomatic [23].…”

Section: Discussionmentioning

confidence: 99%

Histopathological Findings and Clinical Outcomes of Patients After Laparoscopic Sleeve Gastrectomy

Aykota¹,

Yılmaz

2020

International Journal of Health Services Research and Policy

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Laparoscopic sleeve gastrectomy (LSG) has become an increasingly common method for surgical treatment of morbid obesity in recent years. This study aimed to evaluate the histopathological findings of gastrectomy specimens obtained in LSG and the clinical outcomes of patients. Between June 2018 and December 2019, the resected gastric samples of 170 patients with LSG underwent histopathological examination. Histopathologic examination is routinely performed on the gastric specimen that is resected during the sleeve gastrectomy for histopathologic examinations of the severity of inflammation, atrophy, intestinal metaplasia, and H. pylori infection. We found that the most common histopathological findings were chronic gastritis (58.2%), normal gastric mucosa (17.6%), and chronic active gastritis (12.4%). Patients with normal gastric histopathology after LSG lost more weight at the end of the 1st, 3rd, 6th, and 12th months than those with abnormal histopathological findings (chronic gastritis, chronic active gastritis, and edema congestion). Histopathologic examinations are extremely necessary for diagnosing lesions that may have been missed in endoscopies before sleeve gastrectomy. Many factors, such as age, sex, histopathology of the removed stomach, and H. pylori positivity, should be considered in predicting postoperative weight loss success.

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The Relationship Between Histopathologic Findings and Weight Loss in Laparoscopic Sleeve Gastrectomy

Cited by 10 publications

References 14 publications

Association of Hypercholesterolemia With Gastric Intestinal Metaplasia, Findings After Sleeve Gastrectomy Pathology Review

Association of Hypercholesterolemia With Gastric Intestinal Metaplasia, Findings After Sleeve Gastrectomy Pathology Review

Histopathological findings on resected gastric specimens from obese patients undergoing laparoscopic sleeve gastrectomy

Histopathological Findings and Clinical Outcomes of Patients After Laparoscopic Sleeve Gastrectomy

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