Macroscopic Self‐Assembly Based on Complementary Interactions between Nucleobase Pairs

Nakahata, Masaki; Takashima, Yoshinori; Hashidzume, Akihito; Harada, Akira

doi:10.1002/chem.201404674

Cited by 30 publications

(32 citation statements)

References 43 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Simple submersion into an aqueous Pd(OAc) 2 ‐containing solution led to strong bond formation in 5 h, whereas bonding was not observed in the absence of catalyst, even after several days. Ultimate strengths of over 100 kPa were measured, which is significantly higher than the adhesion of H‐bonded (1 kPa) or host–guest gels (up to 10 kPa) ; see Sections and , respectively. Slightly weaker adhesion was observed when gluing the iodophenyl or phenylboronic acid gels to complementary modified glass substrates (10 kPa).…”

Section: Adhesion Through Other Less Explored Interactionsmentioning

confidence: 99%

“…A different approach was taken by Nakahata et al, who prepared DNA hydrogels by copolymerizing acrylamide, bisacrylamide, and a 16‐mer acrylate (i.e., an acrylate bearing an oligonucleotide side group) . Macroscopic self‐assembly of centimeter‐sized pieces of complementary oligo‐DNA gels was observed (rupture stress 1 kPa), while addition of free complementary oligonucleotides inhibited adhesion between the two different DNA gels.…”

Section: Adhesives Based On Hydrogen Bondingmentioning

confidence: 99%

“…Since no residue remained after rupture, such adhesive gels could be interesting for use in biomedical glues or wound dressings (Figure g). It should be noted that the single nucleotide‐functionalized covalently crosslinked hydrogels investigated by Nakahata et al could be promising for use in universal adhesives as well, because the surface of such A‐ or T‐gels should be able to bind to other materials through identical interactions . Unfortunately this property was not tested; this work only focused on the adhesion of dissimilar gels.…”

Section: Adhesives Based On Hydrogen Bondingmentioning

confidence: 99%

See 2 more Smart Citations

Bioinspired Underwater Adhesives by Using the Supramolecular Toolbox

et al. 2018

View full text Add to dashboard Cite

several excellent reviews. [9][10][11][12] Recently, it was emphasized by Waite that catechol moieties alone are insufficient to ensure proper underwater adhesion and that the performance is a complex interplay between DOPA and its local environment. [13] Therefore, attention is shifted to include other (noncovalent) interactions used in these natural glues, and much progress has been made in understanding both their performance and delivery process. [14] In this review, we take the sandcastle worm and mussel as a basis for inspiration. We discuss (noncovalent) interactions found in these natural adhesive systems and extend our discussion to additional supramolecular moieties that can be used to control the adhesive and cohesive performance of synthetically designed adhesives. In Section 2, we examine the natural systems and identify the versatile supramolecular interactions used in such protein-based adhesives. These include electrostatic interactions, hydrogen bonding, hydrophobic forces, π-π interactions, metal coordination, cation-π complexation, and dynamic covalent linkages. The use of these interactions in synthetic adhesive systems is explored in the subsequent sections. Section 3 is devoted to the different interactions that catechols (the functional group of DOPA) display to bond to a submerged substrate or to provide cohesive properties to the adhesive. Despite the fact that catechols have already been the topic of many excellent reviews, [9,13,17] we believe that catechols play a pivotal role in both the sandcastle worm and the mussel adhesive systems and, therefore, should not be omitted from this review. In Section 4, we discuss the use of electrostatic interactions in protein-based and synthetic adhesive formulations for wet conditions. These interactions can be tailored to a wide distribution of bond strengths and thus can be tuned to change multi ple mechanical properties, which is essential for design of an adhesive. Besides the effect on the adhesive and cohesive properties, we highlight work where electrostatic interactions cause liquid-liquid phase separation in aqueous polymer solutions. The resulting (complex) coacervate is a concentrated, liquid, yet water-insoluble phase of the adhesive material, which can act as a powerful delivery tool for underwater adhesives. Hydrogen bonding in adhesives is explored in Section 5. The use of hydrogen bonding to adjust the viscoelastic properties of adhesives has been identified decades, ago, and hydrogen bonding moieties are commonly used in pressure sensitive adhesives (PSAs). However, besides simple, single hydrogen bonding motifs, many interesting alternative Nature has developed protein-based adhesives whose underwater performance has attracted much research attention over the last few decades. The adhesive proteins are rich in catechols combined with amphiphilic and ionic features. This combination of features constitutes a supramolecular toolbox, to provide stimuli-responsive processing of the adhesive, to secure strong adhesion to a variety of...

show abstract

Section: Adhesion Through Other Less Explored Interactionsmentioning

confidence: 99%

Section: Adhesives Based On Hydrogen Bondingmentioning

confidence: 99%

Section: Adhesives Based On Hydrogen Bondingmentioning

confidence: 99%

See 1 more Smart Citation

Bioinspired Underwater Adhesives by Using the Supramolecular Toolbox

et al. 2018

View full text Add to dashboard Cite

show abstract

“…对于分子尺度或纳米级别的构筑基元而言, 作用力程的尺寸范围可以与构筑基元尺寸相比拟, 因而通过表面修饰这些超分子作用的官能团即可实现构筑基元的组装, 甚至可以通过各向异性修饰使构筑基元产生一定的组装取向, 实现程序化组装(programmable assembly), 获得规则有序结构 [41,42] . [19] [46] 、静电吸引 [47] 、碱基配对 [48] 等所驱动的宏观凝胶超分子组装(图7). 进一步, 他们利用具有刺激-响应性的超分子相互作用, 如光 [49] 、pH [50] 、温度 [51] 、溶剂 [52] 、pH/糖 [53] 、氧化还原响应型的 [47] , 可以对宏观动态超分子组装行为进行调 http://engine.scichina.com/doi/10.1360/N032016-00195 图 7 金属配位作用(a, b) [46] 、静电吸引(c) [47] 、碱基配对 (d) [48] 驱动的宏观凝胶超分子组装(网络版彩图) 图 8 DNA杂交驱动(a) [54] 、刺激响应(b) [55] 、四重氢键驱动 (c)的宏观凝胶组装 [56] (网络版彩图) 构变化(图8(b)).…”

Section: 综上作为宏观组装的驱动力磁场力、电场力与毛unclassified

Macroscopic supramolecular assembly: new concept for the fabrication of supramolecular materials

2017

View full text Add to dashboard Cite

show abstract

“…随着构筑基元的尺寸增大, 由于加工局限性等使得构筑基元表面粗糙度较大, 两个宏观构筑基元在接触的瞬间, 其表面修饰的超分子官能团很难达到作用距离内并发生超分子相互作用, 因而宏观构筑基元之间结合强度较低 , 导致宏观超分子组装难以有效发生 [6] . 相互作用 [9] 、金属配位作用 [10] 、离子相互作用 [11] 、碱基配对 [12,13] 等多种超分子相互作用主导的宏观超分子组装, 并研究了组装体在组织工程支架 [14] 、制动器 [15,16] 等方面的应用研究. 除了水凝胶体系, 清华大学唐黎明课题组 [17] 1 实验…”

unclassified