Maggot Debridement Therapy for Diabetic Foot Ulcer: A Case Report

Abstract

Introduction: Diabetic foot problems account for more hospital admissions than any other long term complications of diabetes and are responsible for nearly 50% of all-diabetes-related hospital bed days. Maggot debridement therapy (MDT) offers important advantages for the management of chronic and infected wounds and is used in hundreds of clinics worldwide. This study aimed to evaluate the benefit of maggot debridement therapy (MDT) in the treatment of a patient with a diabetic foot ulcer (DFU). Case Presentation: A 46-year-old male patient with a 6-year-old diabetic foot wound in the right leg. Maggot larvae were placed on the wound. The patient was followed for 6 weeks and luckily had a good response to treatment. Conclusions: This study concluded that MDT is as powerful as traditional debridement in the treatment of diabetic foot ulcers. It would be an achievable different option for diabetic foot ulcer treatment. In conclusion, we observed that MDT could promote wound healing by increasing endothelial proliferation, triggering angiogenesis, and maggot excretion/secretion, which might facilitate this process.

Using a combination therapy to combat scalp necrosis: a case report

“…This keeps the wound free of infection and inflammation to improve wound closure [ 16 ]. In line with our report, the positive impact of MDT on chronic nonhealing wounds has been confirmed in numerous studies [ 1 , 3 , 10 , 15 ]. Futrega et al recommended combination therapies to support effective and reliable wound treatment [ 17 ].…”

“…The promising effect of amniotic membrane grafting (AMG) in treating chronic wounds was confirmed by recent studies [ 8 , 9 ]. Application of modern wound care management in treating chronic nonhealing wounds has recently become very popular in Iran [ 10 – 12 ]. We present one case of a patient with a post-traumatic scalp wound who developed scalp necrosis following reconstructive surgery.…”

COLD-PRESERVATION OF Lucilia sericata (DIPTERA: CALLIPHORIDAE) PUPAE AND ADULT PRODUCTS AS A NEW VENTURE TO ADULTS REARING

“…Further, these larvae feed on necrotic tissues of wound and change the pH of wound from acid to alkaline which leads to stimulation of the repair process. Therefore, due to the risk of damage to vital organs, risk of infection in surgical operations, speed of treatment, recovery in patients and the limited use of antibiotics, maggot therapy is recommended as a selective therapeutic approach (Rafinejad et al, 2014;Alipour et al, 2016;Hajimohammad et al, 2017) In general, the use of larvae on a wound is the last option of defense and it is usually used when a patient has undergone antibiotic and surgical treatment and these two are completely unsuccessful (Rafinejad et al, 2014;Naafs, 2017). In forensic medicine, it is an important marker species used in the survey of the time since death that named post mortem interval (PMI) (Zajac et al, 2018).…”