Magnesium and Citric Acid in the Dissolution of Struvite and Hydroxyapatite

Kroon, A.A.; Baadenhuysen, H.; Froeling, P.

doi:10.1007/978-1-4684-7272-1_197

Cited by 6 publications

(7 citation statements)

References 5 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Experimental investiga tions were carried out to examine the efficacy of various substances as to their ability to dissolve the above-men tioned stones. Citric acid solutions (Suby G, renacidin) showed very good results in the dissolution of calcium phosphate stones [27,28], Calcium oxalate stones, how ever, could not be dissolved either by Suby G solution or by renacidin [8,29], Exeperiments described in the medical literature are confirmed by our own experience. Stone analysis in our patients 1 and 2 showed stones consisting of struvite and apatite, thus allowing for successful treatment by percuta neous chemolysis with Suby G solution.…”

Section: Discussionsupporting

confidence: 68%

When Is the Indication of Percutaneous Chemolysis Justified?

Heimbach¹,

Winter²,

Hesse³

1995

Urol Int

View full text Add to dashboard Cite

Persistent residual stone fragments after extracorporeal Shockwave lithotripsy (ESWL), percutaneous nephrolitholapaxy (PNL) as well as pyelo- and nephrolithotomy represent a great problem in the treatment of stones. The choice of therapy for patients with insufficient renal drainage, poor renal function, and a high anesthetic risk also remains quite difficult. Between 1991 and 1993, 5 patients underwent percutaneous antegrading chemolysis with ‘Suby G’ solution. Two patients, presenting struvite and apatite stones, were free of stones afterwards. In 1 patient, where stone analysis revealed a predominant brushite component, a large decrease in stone size could be observed. In 2 other cases, with stones mainly consisting of whewellite and weddelite, chemolysis proved ineffective. Evaluating our own clinical experience and relevant medical literature, the present study goes on to prove that the indication of percutaneous chemolysis in risk patients as described above is dependent on stone analysis, and must be regarded as an effective adjuvant treatment.

show abstract

Section: Discussionsupporting

confidence: 68%

When Is the Indication of Percutaneous Chemolysis Justified?

Heimbach¹,

Winter²,

Hesse³

1995

Urol Int

View full text Add to dashboard Cite

show abstract

“…Suby and Albright modified the solution by adding magnesium oxide and sodium carbonate (Suby's G solution) [9,10] to reduce injury to the rabbit bladder mucosa even though adding this cation reduced the speed of dissolution of struvite Mg (NH 4 ) PO 4 . A contradictory conclusion was been made by a Dutch study [11] that magnesium in R promotes stone dissolution by cation exchange with calcium in apatite [12]. …”

Section: Discussionmentioning

confidence: 99%

New chemolysis for urological calcium phosphate calculi – a study in vitro

et al. 2005

View full text Add to dashboard Cite

show abstract

“…Various in vitro studies examined the effectiveness of citric acid containing solutions on chemolysis of struvite (5,6,(18)(19)(20). Because of different experimen-tal conditions it is impossible to compare the results of these in vitro studies.…”

Section: Discussionmentioning

confidence: 99%

“…Solutions containing citric acid such as Suby G 1 (5) and Renacidin 1 (6) showed good results (7,8). Solutions containing citric acid such as Suby G 1 (5) and Renacidin 1 (6) showed good results (7,8).…”

mentioning

confidence: 99%