Magnesium Bistrifluoromethanesulfonimide Catalyzed Three-component Synthesis of Protected Homoallylic Amines

Abstract

A mild and efficient procedure has been developed for the one-pot, three-component reaction of aldehydes, benzyl carbamate and allyltrimethylsilane in the presence of 3 mol % of magnesium bistrifluoromethanesulfonimide at room temperature to afford the corresponding protected homoallylic amines in high yields.