Magnesium Intake Is Related to Improved Insulin Homeostasis in the Framingham Offspring Cohort

Rumawas, Marcella Erwina; McKeown, Nicola M.; Rogers, Gail; Meigs, James B.; Wilson, Peter W.F.; Jacques, Paul F.

doi:10.1080/07315724.2006.10719563

Cited by 51 publications

(32 citation statements)

References 48 publications

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“…our results point in the same direction as interventional studies where Mg supplementation improves IS 11,18,20,33 . We observed a higher Matsuda index in the high Mg intake group, reflecting better IS.…”

Section: Anthropometric and Biochemical Measurementssupporting

confidence: 77%

“…However, only a few studies have assessed the relationship between these insulin parameters and Mg intake [20][21][22] . the aim of this study was to evaluate the association between dietary Mg intake and IS in a Mexican-Mestizo population.…”

Section: Anthropometric and Biochemical Measurementsmentioning

confidence: 99%

“…dIsCussIOn the association between serum Mg concentration, IR, and IS has been extensively studied 11,18,20,32 . However, only a few studies have assessed the relationship between these insulin parameters and Mg intake [20][21][22] .…”

Section: Anthropometric and Biochemical Measurementsmentioning

confidence: 99%

“…Several prospective studies where Mg was supplemented and found to exert an improvement in IR 15,18,19 have confirmed these associations. nevertheless, there are few studies associating dietary Mg intake to IR [20][21][22] , so the aim of this study was to determine the association between the average dietary Mg intake and IR estimated by the homeostasis model assessment of insulin resistance (HoMa-IR) and HoMa 2, as well as insulin sensitivity (IS), estimated by the Matsuda IS index and the Hepatic Insulin Resistance Index (HIRI).…”

Section: Introductionmentioning

confidence: 99%

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High Dietary Magnesium Intake is Significantly and Independently Associated with Higher Insulin Sensitivity in a Mexican-Mestizo Population: A Brief Cross-Sectional Report

Moctezuma‐Velázquez

Gómez-Sámano

Cajas-Sánchez

et al. 2017

RIC

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Section: Anthropometric and Biochemical Measurementssupporting

confidence: 77%

Section: Anthropometric and Biochemical Measurementsmentioning

confidence: 99%

Section: Anthropometric and Biochemical Measurementsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

High Dietary Magnesium Intake is Significantly and Independently Associated with Higher Insulin Sensitivity in a Mexican-Mestizo Population: A Brief Cross-Sectional Report

Moctezuma‐Velázquez

Gómez-Sámano

Cajas-Sánchez

et al. 2017

RIC

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show abstract

“…It functions as a critical cofactor for many enzymes involved in energy metabolism, fatty acid synthesis, glucose utilization, and ATPase function. Intracellular magnesium deficiency affects the development of insulin resistance and impairs skeletal muscle glucose uptake (Rumawas et al, 2006). Venu et al (2008) evaluated the effect of maternal magnesium restriction on adiposity, glucose tolerance, and insulin secretion in offspring.…”

Section: Correlations With Mineral Concentrationmentioning

confidence: 99%

Sire breed effect on beef longissimus mineral concentrations and their relationships with carcass and palatability traits

et al. 2015

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The objective of this study was to evaluate sire breed effect on mineral concentration in beef longissimus thoracis (LT) and investigate the correlations between beef mineral concentrations and carcass and palatability traits. Steer progeny (N = 246) from the Germplasm Evaluation project-Cycle VIII were used in this study. In addition to carcass traits, LT was evaluated for mineral concentrations, Warner-Bratzler shear force, and palatability traits. A mixed linear model estimated breed effects on mineral concentrations. No significant sire breed (P ≥ 0.43) or dam breed (P ≥ 0.20) effects were identified for mineral concentrations. Pearson correlation coefficients were calculated among mineral concentrations, carcass, and sensory traits. Zinc concentration was positively correlated (P ≤ 0.05) with total iron (r = 0.14), heme iron (r = 0.13), and magnesium (r = 0.19). Significant (P < 0.05) correlations were identified between non-heme or heme iron and most traits in this study. Magnesium concentration was correlated with all carcass and palatability traits. RightsWorks produced by employees of the U.S. Government as part of their official duties are not copyrighted within the U.S. The content of this document is not copyrighted. The objective of this study was to evaluate sire breed effect on mineral concentration in beef longissimus thoracis (LT) and investigate the correlations between beef mineral concentrations and carcass and palatability traits. Steer progeny (N = 246) from the Germplasm Evaluation project-Cycle VIII were used in this study. In addition to carcass traits, LT was evaluated for mineral concentrations, Warner-Bratzler shear force, and palatability traits. A mixed linear model estimated breed effects on mineral concentrations. No significant sire breed (P ≥ 0.43) or dam breed (P ≥ 0.20) effects were identified for mineral concentrations. Pearson correlation coefficients were calculated among mineral concentrations, carcass, and sensory traits. Zinc concentration was positively correlated (P ≤ 0.05) with total iron (r = 0.14), heme iron (r = 0.13), and magnesium (r = 0.19). Significant (P b 0.05) correlations were identified between non-heme or heme iron and most traits in this study. Magnesium concentration was correlated with all carcass and palatability traits.

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Whole grains, type 2 diabetes, coronary heart disease, and hypertension: Links to the aleurone preferred over indigestible fiber

et al. 2013

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Higher whole grain cereal intakes are associated with substantially lower risks of type 2 diabetes, coronary heart disease, and hypertension. These reduced risks have been established in large prospective studies that now include millions of person-years of follow-up. We analyze the results of 11 major prospective studies to provide recommendations about whole grain consumption. The following review establishes the amount of whole grains that should ideally be consumed based on prospective evidence; defines the nature of whole grains; identifies that the whole grain evidence is robust and not due to confounding; and provides a detailed assessment of several potential mechanisms for the effect of whole grains on health. We draw the following conclusions. Firstly, to maintain health, 40 grams or more of whole grains should be consumed daily. This is about a bowl of whole grain breakfast cereal daily, but 80% of the population does not achieve this. Secondly, aleurone in bran is a critical grain component generally overlooked in favor of indigestible fiber. Live aleurone cells constitute 50% of millers’ bran. They store minerals, protein, and the antioxidant ferulic acid, and are clearly more than just indigestible fiber. Finally, we suggest potential roles for magnesium, zinc, and ferulic acid in the development of chronic disease. If the results of prospective studies were applied to the life-style practices of modern societies there exists the potential for enormous personal health and public financial benefits.

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Magnesium Intake Is Related to Improved Insulin Homeostasis in the Framingham Offspring Cohort

Abstract: Improved insulin sensitivity may be one mechanism by which higher dietary magnesium intake may reduce the risk of developing type 2 DM.

Cited by 51 publications

References 48 publications

High Dietary Magnesium Intake is Significantly and Independently Associated with Higher Insulin Sensitivity in a Mexican-Mestizo Population: A Brief Cross-Sectional Report

High Dietary Magnesium Intake is Significantly and Independently Associated with Higher Insulin Sensitivity in a Mexican-Mestizo Population: A Brief Cross-Sectional Report

Sire breed effect on beef longissimus mineral concentrations and their relationships with carcass and palatability traits

Whole grains, type 2 diabetes, coronary heart disease, and hypertension: Links to the aleurone preferred over indigestible fiber

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