Magnetic-Field-Assisted Assembly of Layered Double Hydroxide/Metal Porphyrin Ultrathin Films and Their Application for Glucose Sensors

Abstract

The ordered ultrathin films (UTFs) based on CoFe-LDH (layered double hydroxide) nanoplatelets and manganese porphyrin (Mn-TPPS) have been fabricated on ITO substrates via a magnetic-field-assisted (MFA) layer-by-layer (LBL) method and were demonstrated as an electrochemical sensor for glucose. The XRD pattern for the film indicates a long-range stacking order in the normal direction of the substrate. Scanning electron microscopy (SEM) and atomic force microscopy (AFM) images of the MFA LDH/Mn-TPPS UTFs reveal a continuous and uniform surface morphology. Cyclic voltammetry, impedance spectroscopy, and chronoamperometry were used to evaluate the electrochemical performance of the film, and the results show that the MFA-0.5 (0.5 T magnetic field) CoFe-LDH/Mn-TPPS-modified electrode displays the strongest redox current peaks and fastest electron transfer process compared with those of MFA-0 (without magnetic-field) and MFA-0.15 (0.15 T magnetic field). Furthermore, the MFA-0.5 CoFe-LDH/Mn-TPPS exhibits remarkable electrocatalytic activity toward the oxidation of glucose with a linear response range (0.1-15 mM; R(2) = 0.999), low detection limit (0.79 μM) and high sensitivity (66.3 μA mM(-1) cm(-2)). In addition, the glucose sensor prepared by the MFA LBL method also shows good selectivity and reproducibility as well as resistance to poisoning in a chloride ion solution. Therefore, the novel strategy in this work creates new opportunities for the fabrication of nonenzyme sensors with prospective applications in practical detection.

Tailoring Hybrid Layered Double Hydroxides for the Development of Innovative Applications

“…Charge overcompensation occurs after every adsorption step, which allows the adsorption of the subsequent oppositely charged layers. It should be underlined that a magnetic field can be used in a sophisticated way to promote the LbL assembly of magnetically responsive CoFe LDH in ordered thin films . The assembly process can be monitored by UV–vis or fluorescence spectroscopy to obtain a stepwise and regular growth of the thin films upon increasing the deposited cycles.…”

Application of the electronic spectra of porphyrins for analytical purposes: The effects of metal ions and structural distortions

“…Numerous analytical methods for determination of organic compounds were developed by utilization of porphyrins: e.g. for nucleic acids [28,42,57,58,59] (porphyrin exciton coupled circular dichroism [57] for other chiral agents too), aminoacids and proteins [48,60,61], carbohydrates [28,62,63], phenols and chlorophenols [64], phenolic endocrine compounds [65], hormones [66], non-ionic surfactants [67], phospholipids [68], sulphur-containing hydrocarbons [48,69], and explosives [70]. Most of these analytical methods are based on the spectrophotometric properties (absorption, light scattering and fluorescence) of porphyrins, therefore in this work we would like to summarize and complement the knowledge in this area of porphyrin-chemistry from analytical aspects.…”

Layered Hydroxide–Porphyrin Hybrid Materials: Synthesis, Structure, and Properties

“…[64] The electrode that contained only glassy carbon modified with pure CoPcS or with CoPcS adsorbed onto Zn 3 Al-LDH showed lower electrocatalytic activity and stability relative to an electrode modified with CoPcS intercalated in Zn 3 Al-LDH-CoPcS. [67] Gaillon et al were the first to describe the electrochemical behavior of MnTPPS on MgAl-based LDHs. This strategy was employed for the preparation of an Mg 2 Al-LDH-CoPcS thin film that exhibited a low detection limit, fast response, and long-term stability for dopamine sensing.…”