Magnetic nanosorbents with siliceous hybrid shells of alginic acid and carrageenan for removal of ciprofloxacin

Soares, Sofia F.; Rocha, Maria João; Ferro, Marta C.; Amorim, Carlos O.; Amaral, J. S.; Trindade, Tito; Daniel‐da‐Silva, Ana L.

doi:10.1016/j.ijbiomac.2019.08.030

Cited by 45 publications

(33 citation statements)

References 86 publications

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“…In the past few years, our research group has developed a new strategy for the preparation of core/shell spheroidal nanoparticles, comprising magnetite cores (Fe 3 O 4 ) coated with amorphous silica shells [50], or with siliceous shells enriched in polymers from renewable sources including starch [51], alginate [52], chitosan [53,54] and carrageenan [51,55]. We aimed at creating magnetic bionanocomposites whose ability to interact with target molecular species depends on the chemical functionalities of the shells.…”

Section: Characterization Of the Magnetic Nanocarriersmentioning

confidence: 99%

Magnetic Driven Nanocarriers for pH-Responsive Doxorubicin Release in Cancer Therapy

et al. 2020

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Doxorubicin is one of the most widely used anti-cancer drugs, but side effects and selectivity problems create a demand for alternative drug delivery systems. Herein we describe a hybrid magnetic nanomaterial as a pH-dependent doxorubicin release carrier. This nanocarrier comprises magnetic iron oxide cores with a diameter of 10 nm, enveloped in a hybrid material made of siliceous shells and ĸ-carrageenan. The hybrid shells possess high drug loading capacity and a favorable drug release profile, while the iron oxide cores allows easy manipulation via an external magnetic field. The pH responsiveness was assessed in phosphate buffers at pH levels equivalent to those of blood (pH 7.4) and tumor microenvironment (pH 4.2 and 5). The nanoparticles have a loading capacity of up to 12.3 wt.% and a release profile of 80% in 5 h at acidic pH versus 25% at blood pH. In vitro drug delivery tests on human breast cancer and non-cancer cellular cultures have shown that, compared to the free drug, the loaded nanocarriers have comparable antiproliferative effect but a less intense cytotoxic effect, especially in the non-cancer cell line. The results show a clear potential for these new hybrid nanomaterials as alternative drug carriers for doxorubicin.

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Section: Characterization Of the Magnetic Nanocarriersmentioning

confidence: 99%

Magnetic Driven Nanocarriers for pH-Responsive Doxorubicin Release in Cancer Therapy

et al. 2020

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“…Such isotherms are concave to the horizontal x-axis at low liquid-phase concentrations and convex at higher liquid-phase concentrations (type V isotherm shape according to the BDDT classification). Some recent examples include the works of Soares et al [6], Jiang et al [7], Mitrogiannis et al [8], and Gago et al [9]. Soares et al [6] reported the uptake of the antibiotic ciprofloxacin by a silica-based magnetic nanosorbent.…”

Section: Introductionmentioning

confidence: 99%

“…Some recent examples include the works of Soares et al [6], Jiang et al [7], Mitrogiannis et al [8], and Gago et al [9]. Soares et al [6] reported the uptake of the antibiotic ciprofloxacin by a silica-based magnetic nanosorbent. The equilibrium data set displaying a sigmoidal profile was reasonably well fitted by the Dubinin-Radushkevich isotherm.…”

Section: Introductionmentioning

confidence: 99%

“…. In this work, three sets of previously published equilibrium data of water contaminants are used to test the Krishnamurti isotherm: (1) ammonium ion adsorption by sepiolite[20], (2) ciprofloxacin removal by a magnetic nanosorbent[6], and (3) fluoride ion adsorption by a layered double hydroxide adsorbent[21].4.1. Ammonium ion adsorption by sepioliteFig.…”

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“…2. (A) Krishnamurti isotherm fit (solid line, N0 = 819.7 mg/g; k1 = 0.03 L/mg; k2 = 651.7) compared to observed ciprofloxacin equilibrium data; (B) residual plot.Soares et al[6] synthesized three different types of magnetic nanoparticles which were used to remove the antibiotic ciprofloxacin from aqueous solutions. Of interest to the present study are the equilibrium characteristics of the three adsorption systems.…”

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Fitting a little-known isotherm equation to S-shaped adsorption equilibrium data

Chu¹

2021

Separation and Purification Technology

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A research topic of current interest concerns the measurement and modeling of adsorption equilibrium isotherms of water contaminants. The bulk of measured equilibrium isotherms exhibit the convex-upward or favorable curve shape, which can be described by the two-parameter Langmuir and Freundlich isotherms. An increasing number of recent studies have however reported S-shaped or sigmoidal equilibrium isotherms. Modeling such equilibrium data requires the use of isotherm equations with a highly flexible functional form. This work introduces a little-known isotherm useful for tracking the trajectory of S-shaped equilibrium data. This relatively simple three-parameter isotherm, first proposed by Krishnamurti in 1951, has theoretical merit because it is based on a cooperative adsorption mechanism. It is shown that previously published S-shaped equilibrium data of water contaminants can be represented by the Krishnamurti isotherm. Specific examples discussed are (1) ammonium ion adsorption by the clay mineral sepiolite, (2) uptake of the antibiotic ciprofloxacin by a magnetic nanosorbent, and (3) fluoride ion removal by a layered double hydroxide adsorbent. Further, it is found that a modified form of the Krishnamurti isotherm is superior to its original counterpart in tracing sigmoidal equilibrium data. The original and modified Krishnamurti isotherms can be practically very useful to describe S-shaped equilibrium data and for adsorptive process modeling.

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Attached culture of Gibberella fujikuroi for biocomposite sorbent production and ciprofloxacin sequestration applications

Akar

Sayin

Çelik

et al. 2021

J of Chemical Tech & Biotech

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BACKGROUND The fluoroquinolone antibiotics in water sources are significant threats to public health, as well as the water ecosystem and water reuse. In this study, the feasibility of the biosorption of ciprofloxacin (CIP) using pine needles biomass‐Gibberella fujikuroi immobilized biocomposite (PNGFB) was promoted. It was prepared by passive cell immobilization onto the lignocellulosic matrix. The suggested biosorbent was characterized by Fourier Transform Infrared (FTIR) analysis, Scanning Electron Microscope (SEM), and zeta potential analysis. Series of batch and continuous mode experiments were conducted. RESULTS The results of both systems showed that the PNGFB was effectively used for the treatment of CIP contamination. The maximum uptake occurred at pH 6.0, 40 min contact time, 1.0 mL min−1 flow rate, and 0.10 g (batch) and 0.20 g (column) PNGFB dosages. Redlich–Peterson isotherm model was the best suited to equilibrium data and the pseudo‐second‐order model predicted the biosorption kinetics. The maximum monolayer biosorption capability was 39.17 mg g−1. The suggested biocomposite also reached CIP removal yields of 64.14% and 53.74% in synthetic hospital effluent and synthetic urine samples containing 100 mg L−1 antibiotic, respectively. The regeneration study indicates that PNGFB retained its high biosorption and desorption yields during five cycles of the biosorption‐desorption. CONCLUSION The findings clearly showed that the PNGFB seems to be an eco‐friendly, effective, economic, and potentially viable biocomposite sorbent for the sustainable removal of CIP contamination. © 2021 Society of Chemical Industry (SCI).

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Magnetic nanosorbents with siliceous hybrid shells of alginic acid and carrageenan for removal of ciprofloxacin

Cited by 45 publications

References 86 publications

Magnetic Driven Nanocarriers for pH-Responsive Doxorubicin Release in Cancer Therapy

Magnetic Driven Nanocarriers for pH-Responsive Doxorubicin Release in Cancer Therapy

Fitting a little-known isotherm equation to S-shaped adsorption equilibrium data

Attached culture of Gibberella fujikuroi for biocomposite sorbent production and ciprofloxacin sequestration applications

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