Magnetic porous aromatic framework with a core–shell structure as a sorbent for rapid extraction of phenols and their quantitation in urine by HPLC-UV

Abstract

A porous aromatic framework (PAF) is shown to be a viable sorbent for the adsorption of phenols. To overcome the difficulty of quick adsorption and enrichment by phenols from the matrix, a sorbent material consisting of porous aromatic framework magnetic nanoparticles (PAF MNPs) with a core-shell structure was fabricated by an in situ growth method. The PAF MNP sorbent was characterized by transmission electron microscopy, Fourier transform infrared spectroscopy and other techniques. The factors affecting enrichment performance including the amount of PAF-6 MNPs, sample pH, extraction time and elution conditions were optimized. Under the optimal conditions, a method utilizing high-performance liquid chromatography with an ultraviolet detector (HPLC-UV) was developed to quantify phenols in urine. The method showed good linearity (r ≥ 0.998), good precision (RSD ≤ 9.9%, n = 6) and a low limit of detection (1.0-2.0 ng/mL, S/N = 3), with recoveries performed in urine matrix ranging from 76.7% to 113.2%. The method is simple, time-saving and sensitive. Moreover, compared with traditional mass spectrometry detection methods, this method has advantages in terms of low cost and repeatability.

Development of a needle trap device packed with modified PAF-6-MNPs for sampling and analysis of polycyclic aromatic compounds in air

“…PAFs have been widely employed for sampling various compounds in different matrices such as water, soil, biological tissues, and plant tissues using various sampling methods. [24][25][26] However, to date, no study has explored the application of NTD packed with PAF-6 for single step sampling and analysis of pollutants from air.…”

Extraction Systems and Analytical Techniques for Food Phenolic Compounds: A Review

“…Two variants of this technique, known as dispersive and magnetic solid-phase extraction (d-SPE and M-SPE, respectively), have been recently evaluated as clean-up steps for the analysis of phenolic compounds in Myrciaria cauliflora (or Plinia cauliflora ) peel [ 80 ] and oilseeds [ 81 ]. In d-SPE, the sorbent (e.g., diatomaceous earth) is added directly to the extract and not packed into a column or cartridge while the second one uses magnetic nanoparticles of iron oxide or graphene [ 82 ].…”

Three‐dimensional flower‐like SnS2 materials for dispersive solid‐phase extraction of endocrine‐disrupting phenols

“…Due to the low concentration level and complex matrix, sample pretreatment is an essential step for the detection of trace EDPs. At present, adsorbent‐based extraction and solvent‐based extraction are the most typical sample preparation techniques used for the enrichment of endocrine disrupting chemicals and EDPs, including SPME [6], SPE [7], liquid‐liquid extraction [8], magnetic SPE [9], dispersive liquid‐liquid microextraction [10] and dispersive SPE (dSPE) [2]. Compared with solvent‐based extraction, adsorbent‐based extraction was more popular as a smaller amount of organic solvent was commonly used.…”