Magnetic resonance imaging basics for the prostate brachytherapist

Wang, Jihong; Tanderup, Kari; Cunha, A.; Damato, Antonio L.; Cohen, Gil’ad N.; Kudchadker, Rajat J.; Mourtada, Firas

doi:10.1016/j.brachy.2017.03.004

Cited by 18 publications

(32 citation statements)

References 67 publications

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“…It is essential to considered field strength as it influences signal-to-noise (SNR) ratio, geometric-distortions (GD), and artifacts in imaging. It is recommended to target minimal GD of the prostate for MRI-guided LDR-BT [4]. 3 T scanners generate high-resolution images, improving tissues' delineations for dose delivery, especially for intraprostatic tumor dosage boost.…”

Section: ) Mr Based Prostate Interventionsmentioning

confidence: 99%

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Review of Clinical and Technological Consideration for MRI-Guided Robotic Prostate Brachytherapy

Dhaliwal

Chettibi

Wilby

et al. 2021

IEEE Trans. Med. Robot. Bionics

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Low Dose Rate Brachytherapy (LDR-BT) is a technique for treating localized prostate cancer by implanting radioactive seeds. In conventional practice, the delivery of seeds is performed using transrectal ultrasonography (TRUS) imaging for implant guidance and checked using computed-tomography for post-implant dosimetry. In the case of TRUS, accuracy can be compromised due to sub-optimal imaging. Magnetic Resonance Imaging (MRI), however, is known to provide better soft-tissue contrast, therefore, increasing the ability to detect small lesions; for that reason, the integration of intraoperative MRI in BT workflows has been investigated over the last two decades. The fusion of preoperative MR-images during TRUS-brachytherapy is possible. However, the image registration process introduces a source of uncertainty. Manual, real-time intra-operative LDR-BT is challenging under MRI due to confined space and procedural workflows. This motivates the development of MRI-compatible robots for prostate BT, with potential advantages of improved source placement accuracy and final dosimetry. In this paper, the state-of-art of technological components in MRI compatible robots, especially for LDR-BT, has been presented. This systematic review helps us to position an ongoing Cooperative Brachytherapy project, developing a real-time MRI-guided robot for adaptive LDR-BT. The design approach includes integrating separate modules: imaging, dose planning, needles, and robot.

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Section: ) Mr Based Prostate Interventionsmentioning

confidence: 99%

“…Since the application of MRI in radiotherapy is under clinical research at rapid rate due to its precision and its increasing availability, particularly for BT [3], [4]. MRI provides superior discrimination of intraprostatic lesions and OARs critical in radiation oncology for improved target localization and accurate treatment planning.…”

Section: Introductionmentioning

confidence: 99%

Review of Clinical and Technological Consideration for MRI-Guided Robotic Prostate Brachytherapy

Dhaliwal

Chettibi

Wilby

et al. 2021

IEEE Trans. Med. Robot. Bionics

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“…Standardized application of mpMRI in combination with distinct biopsy procedures allows precise therapy planning for surgical as well as for focal therapeutic procedures (e.g., high-intensity focused ultrasound or cryotherapy) and brachytherapy [71][72][73]. As part of advanced PCa screenings with a high rate of low-risk cancers, personalized therapy approaches have gained more significance due to lower complication rates when compared to more aggressive therapy approaches [74].…”

Section: Role Of Mpmrimentioning

confidence: 99%

Multiparametric prostate MRI and structured reporting: benefits and challenges in the PI-RADS era

Mir-Bashiri¹,

Yaqubi

Woźnicki

et al. 2021

Chin J Acad Radiol

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Prostate cancer (PCa) is the second most frequent cancer diagnosis in men and the sixth leading cause of cancer death worldwide with increasing numbers globally. Therefore, differentiated diagnostic imaging and risk-adapted therapeutic approaches are warranted. Multiparametric magnetic resonance imaging (mpMRI) of the prostate supports the diagnosis of PCa and is currently the leading imaging modality for PCa detection, characterization, local staging and image-based therapy planning. Due to the combination of different MRI sequences including functional MRI methods such as diffusion-weighted imaging (DWI) and dynamic contrast-enhanced MRI (DCE-MRI), mpMRI enables a high sensitivity and specificity for the detection of PCa. The rising demand for individualized treatment strategies requires methods to ensure reproducibility, completeness, and quality of prostate MRI report data. The PI-RADS (Prostate Imaging Reporting and Data System) 2.1 classification represents the classification system that is internationally recommended for MRI-based evaluation of clinically significant prostate cancer. PI-RADS facilitates clinical decision-making by providing clear reporting parameters based on clinical evidence and expert consensus. Combined with software-based solutions, structured radiology reports form the backbone to integrate results from radiomics analyses or AI-applications into radiological reports and vice versa. This review provides an overview of imaging methods for PCa detection and local staging while placing special emphasis on mpMRI of the prostate. Furthermore, the article highlights the benefits of software-based structured PCa reporting solutions implementing PI-RADS 2.1 for the integration of structured data into decision support systems, thereby paving the way for workflow automation in radiology.

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“…Although TRUS is the current standard for measuring preimplant dosimetry in LDRPB, an increase in the integration of MRI into the LDRPB workflow has been seen recently (10). This integration has been met with some challenges (10,11). Retrospective and prospective studies on MRI-based treatment planning have been performed (11e14).…”

Section: Introductionmentioning

confidence: 99%

A comparison of treatment planning techniques for low-dose-rate (LDR) prostate brachytherapy

et al. 2021

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The purpose of this study was to compare low-dose-rate prostate brachytherapy treatment plans created using three retrospectively applied planning techniques with plans delivered to patients. METHODS AND MATERIALS: Treatment plans were created retrospectively on transrectal ultrasound (TRUS) scans for 26 patients. The technique dubbed 4D Brachytherapy was applied, using TRUS and MRI to obtain prostatic measurements required for the associated webBXT online nomogram. Using a patient's MRI scan to create a treatment plan involving loose seeds was also explored. Plans delivered to patients were made using an intraoperative loose seed TRUS-based planning technique. Prostate V 100 (%), prostate V 150 (%), prostate D 90 (Gy), rectum D 0.1cc (Gy), rectum D 2cc (Gy), urethra D 10 (%), urethra D 30 (%), and prostate volumes were measured for each patient. Statistical analysis was used to assess and compare plans. RESULTS: Prostate volumes measured by TRUS and MRI were significantly different. Prostate volumes calculated by the webBXT online nomogram using TRUS-and MRI-based measurements were not significantly different. Compared with delivered plans, TRUS-based 4D Brachytherapy plans showed significantly lower rectum D 0.1cc (Gy) values, MRI-based 4D Brachytherapy plans showed significantly higher prostate V 100 (%) values and significantly lower rectum D 0.1cc (Gy), urethra D 10 (%), and urethra D 30 (%) values, and loose seed MRI-based plans showed significantly lower prostate V 100 (%), prostate D 90 (Gy), rectum D 0.1cc (Gy), rectum D 2cc (Gy), urethra D 10 (%), and urethra D 30 (%) values. CONCLUSIONS: TRUS-based 4D Brachytherapy plans showed similar dosimetry to delivered plans; rectal dosimetry was superior. MRI can be integrated into the 4D Brachytherapy workflow. The webBXT online nomogram overestimates the required number of seeds.

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Magnetic resonance imaging basics for the prostate brachytherapist

Cited by 18 publications

References 67 publications

Review of Clinical and Technological Consideration for MRI-Guided Robotic Prostate Brachytherapy

Review of Clinical and Technological Consideration for MRI-Guided Robotic Prostate Brachytherapy

Multiparametric prostate MRI and structured reporting: benefits and challenges in the PI-RADS era

A comparison of treatment planning techniques for low-dose-rate (LDR) prostate brachytherapy

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