Magnetic resonance imaging findings of styloglossus and hyoglossus muscle invasion: Relationship to depth of invasion and clinical significance as a predictor of advisability of elective neck dissection in node negative oral tongue cancer

Baba, Akira; Okuyama, Yumi; Yamauchi, Hideomi; Ikeda, Koshi; Ogino, Nobuhiro; Kozakai, Ayako; Suzuki, Taiki; Saito, Hirokazu; Ogane, Satoru; Yamazoe, Sadaaki; Mogami, Takuji; Ojiri, Hiroya

doi:10.1016/j.ejrad.2019.06.023

Cited by 17 publications

(16 citation statements)

References 26 publications

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“…In addition, UICC/AJCC 8th edition removed invasion to the external lingual muscle from the T classification, but previous reports have indicated that the external lingual muscle appears to be relatively shallow from the normal mucosa [ 48 ]. It is reported that DOI can be judged more than 4 mm in cases of invasion to the styloglossus and hyoglossus muscles [ 49 ] and that cervical lymph node metastasis is more frequent in cases of invasion to the paralingual space [ 50 ]. In preoperative diagnostic imaging, not only DOI measurement, but also detailed evaluation of the presence or absence of invasion to the external lingual muscles is necessary.…”

Section: Discussionmentioning

confidence: 99%

A comparative study between CT, MRI, and intraoral US for the evaluation of the depth of invasion in early stage (T1/T2) tongue squamous cell carcinoma

et al. 2021

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Objectives This study aimed to clarify the accuracy of intraoral ultrasonography (US), computed tomography (CT), and magnetic resonance imaging (MRI) in preoperative image depth of invasion (DOI) measurement of T1/T2 tongue cancer through comparison with histopathological measurements. Methods Imaging of the primary lesions was performed at our hospital; the lesions were classified into T1 and T2 based on the 8th edition of the AJCC/UICC, and surgery performed. There was histopathological confirmation of lesions as squamous cell carcinoma in 48 patients with tongue cancer. T3 and T4 cases, cases in which preoperative chemotherapy and radiation therapy were performed, and cases where biopsy was performed before imaging were excluded. The radiological DOI in US, CT, and MRI and the histopathological DOI as base were comparatively investigated and statistical analyses were performed by Bland–Altman analysis and Spearman's rank correlation coefficient. Results Bland–Altman analysis showed that the US radiological DOI was overestimated by an average of 0.2 mm compared to the histopathological DOI, while CT and MRI radiological DOI were overestimated by an average of 2–3 mm. The comparison of CT and MRI revealed that the difference between the MRI and histopathological DOI, as well as the 95% limit of agreement, were smaller than those of the CT radiological DOI. Conclusions US is the most accurate preoperative diagnostic tool for T1 and T2 squamous cell carcinoma; CT and MRI tend to have an overestimation of about 2–3 mm and so caution is required.

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Section: Discussionmentioning

confidence: 99%

A comparative study between CT, MRI, and intraoral US for the evaluation of the depth of invasion in early stage (T1/T2) tongue squamous cell carcinoma

et al. 2021

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“…Some researchers thought that T2WI was better for measurement than T1WI [9,18]; others had the opposite view [13]. Baba et al [16] reported that the measurement of CE-T1WI-derived DOI was slightly more accurate than that of T2WI-derived DOI for a better correlation between CE-T1WI-derived DOI and histopathological DOI. Another point of view was that optimal MR sequence differed for each patient [14,15].…”

Section: Discussionmentioning

confidence: 99%

“…Due to its excellent soft tissue resolution, magnetic resonance imaging (MRI) is widely applied in the assessment of clinical DOI of OTSCC [9][10][11][12][13][14][15][16][17]. However, MRI-derived DOI was statistically larger than histopathological DOI [9,[13][14][15] due to peritumor edema or inflammation, which might lead to overestimated clinical T staging.…”

Section: Introductionmentioning

confidence: 99%

Assessment of tumor depth in oral tongue squamous cell carcinoma with multiparametric MRI: correlation with pathology

et al. 2021

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Objectives To compare the correlation of depth of invasion (DOI) measured on multiple magnetic resonance imaging (MRI) sequences and pathological DOI, in order to determine the optimal MRI sequence for measurement. Methods A total of 122 oral tongue squamous cell carcinoma (OTSCC) patients were retrospectively analyzed, who had received preoperative MRI and surgical resection. DOIs measured on fat-suppressed T2-weighted imaging (T2WI), diffusion-weighted imaging (DWI), dynamic enhanced-T1 high-resolution insotropic volume examination (e-THRIVE), and contrast-enhanced fat-suppressed T1WI (CE-T1WI) were respectively compared to those measured in pathologic specimens. The cutoff value of the best correlated MRI sequence was determined, and the T staging accuracy of MRI-derived DOI was evaluated. Results DOI derived from e-THRIVE showed the best correlation (r = 0.936, p < 0.001) with pathological DOI. The area under the curve values of MRI-derived DOI distinguishing T1 stage from T2 stage and distinguishing T2 stage from T3 stage were 0.969 and 0.974, respectively. The T staging criteria of MRI-derived DOI were 6.2 mm and 11.4 mm, with a staging accuracy of 86.9% compared to pathological DOI criteria of 5 mm and 10 mm. Conclusion E-THRIVE was the optimal MR sequence to measure the MR-derived DOI, and DOI derived from e-THRIVE could serve as a potential cut-off value as a clinical T staging indicator of OTSCC. Key Points • Multiparametric MRI helps radiologists to assess the neoplasm invasion in patients with oral tongue squamous cell carcinoma. • Retrospective study indicated that measurement was most accurate on enhanced-T1 high-resolution insotropic volume examination dynamic contrast enhancement images. • T staging of oral tongue squamous cell carcinoma was accurate according to the dynamic contrast enhancement MRI-derived depth of invasion.

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“…The correlation of MR‐DOI and P‐DOI had been assessed among 49 cases, with the coefficient of 0.949 for tongue and much lower for other anatomical sites (Park et al., 2011). In most literatures, the correlation coefficients were reported of over 0.68 of tumour dimensions between MRI and pathology for tongue cancer (Baba et al, 2019b; Goel et al., 2016; Lam et al., 2004; Preda et al., 2006; Yesuratnam et al., 2014).…”

Section: Discussionmentioning

confidence: 99%

Assessing the magnetic resonance imaging in determining the depth of invasion of tongue cancer

Zhu

et al. 2020

Oral Diseases

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Objectives To assess the magnetic resonance imaging (MRI) in predicting tumour's depth of invasion (DOI) of tongue cancer by comparing to pathology and to determine the cut‐off value of MRI‐derived DOI for lymph node metastasis. Patients and methods In a retrospective analysis, 156 patients with newly diagnosed tongue cancer were included. Tumour's DOI was compared between MRI measurement and pathology by Pearson correlation coefficient and paired t test. The accuracy of MRI‐derived DOI was compared to the pathological DOI. The relationship between MRI‐derived DOI and cervical lymph node metastasis was calculated by receiver operating characteristic curve. Results Tumour's DOI was well correlated between MRI measurement and pathology with correlation coefficients of 0.77. MRI‐derived DOI was 3.4 mm (28%) larger than pathology. The accuracy of MRI in deciding pathological DOI was 67.9%. The cut‐off value of MRI‐derived DOI was 10.5 mm for lymph node metastasis of tongue cancer. Conclusion Magnetic resonance imaging can be used as a reference to determine tumour's DOI of tongue cancer. Tumour with MRI‐derived DOI larger than 10.5 mm deserves simultaneous neck dissection at initial surgery.

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Magnetic resonance imaging findings of styloglossus and hyoglossus muscle invasion: Relationship to depth of invasion and clinical significance as a predictor of advisability of elective neck dissection in node negative oral tongue cancer

Cited by 17 publications

References 26 publications

A comparative study between CT, MRI, and intraoral US for the evaluation of the depth of invasion in early stage (T1/T2) tongue squamous cell carcinoma

A comparative study between CT, MRI, and intraoral US for the evaluation of the depth of invasion in early stage (T1/T2) tongue squamous cell carcinoma

Assessment of tumor depth in oral tongue squamous cell carcinoma with multiparametric MRI: correlation with pathology

Assessing the magnetic resonance imaging in determining the depth of invasion of tongue cancer

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