Magnetic Resonance Imaging in Inflammatory Bowel Disease

Shoenut, J P; Semelka, Richard C.; Silverman, Richard; Yaffe, C S; Micflikier, Allan B.

doi:10.1097/00004836-199307000-00018

Cited by 93 publications

(59 citation statements)

References 3 publications

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“…Our hypothesis is supported by earlier studies (2,38) that showed low correlation coefficients between CDEIS and CDAI, and between individual MR parameters and CDAI (28). To our knowledge, seven prospective studies have examined the accuracy of MRI for assessing CD in an adult population using endoscopy as the gold standard (27)(28)(29)(30)(31)(32)(33). However, in all but two of these studies besides CD patients (29,32), also patients with ulcerative colitis (UC) were included.…”

Section: Discussionsupporting

confidence: 71%

“…However, differences in appraising these aspects contributed to the low interobserver values since, in addition to mesenteric hypervascularization, enhancement of bowel segments was rated differently by the two observers in 75 of 151 assessable segments. In the literature contrast enhancement has been described as one of the most important parameters that indicate active disease (9,27,29). However, in these studies quantitative measurements of percentage of contrast enhancement were obtained only from the most diseased segment of bowel, and were subsequently correlated with endoscopic findings.…”

Section: Discussionmentioning

confidence: 99%

“…However, before MRI can be considered an alternative for endoscopy in CD, it should be firmly established that in addition to detecting disease activity, MRI is capable of revealing both the severity and the exact location of disease. A few prospective studies have compared MRI with endoscopy regarding the severity of disease, but only the five most recent of these studies also analyzed the accuracy of MRI for localizing disease (27)(28)(29)(30)(31)(32)(33). The results of these studies were conflicting, and the reported sensitivities and specificities varied widely from approaching endoscopic accuracy to considerable over-or underestimation of disease.…”

mentioning

confidence: 99%

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Feasibility of evaluating Crohn's disease activity at 3.0 Tesla

Gemert-Horsthuis

Florie

Hommes

et al. 2006

Magnetic Resonance Imaging

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Purpose: To determine whether abdominal 3.0T MRI can be used for evaluation of Crohn's disease (CD) compared with ileocolonoscopy (CS), and to determine patient preference for MRI as opposed to CS. Materials and Methods:Twenty patients scheduled for CS underwent MRI. At CS, disease severity was graded and the Crohn's Disease Endoscopic Index of Severity (CDEIS) was determined. Radiological grading (by two observers) was compared with endoscopic grading and CDEIS. Patient experience and preference were determined. Results:In respectively 10 (observer 1) and 13 patients (observer 2) exact agreement between radiological and endoscopic grading was found. In respectively 10 and 7 patients radiological and endoscopic grading differed one level. No statistically significant correlation was found between radiological grading and CDEIS. Between bowel wall thickness and CDEIS weak to moderate correlations were found, and between bowel wall enhancement and CDEIS weak correlations were found. All patients preferred MRI over CS. Conclusion:It is feasible to perform abdominal 3.0T MRI using orally administered contrast medium for evaluation of CD, and this method can be considered a patient-friendly alternative to CS.

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Section: Discussionsupporting

confidence: 71%

Section: Discussionmentioning

confidence: 99%

mentioning

confidence: 99%

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Feasibility of evaluating Crohn's disease activity at 3.0 Tesla

Gemert-Horsthuis

Florie

Hommes

et al. 2006

Magnetic Resonance Imaging

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“…While this method provides adequate data regarding intestinal involvement in the jejunum and ileum, it has provided no direct information concerning extraintestinal intra-abdominal processes associated with this disease. Since the introduction of faster imaging techniques (e.g., breath-hold) [1] and the availability of oral magnetic resonance contrast media [2,3] in the mid-1990s, MRI has played an increasing role in the diagnosis of chronic inflammatory bowel diseases [4,5]. Magnetic resonance imaging visualizes involved bowel segments, stenoses, and fistulae, in addition to abscesses, adipose tissue hyperplasia, and lymphadenopathies without radiation exposure for the patient.…”

Section: Introductionmentioning

confidence: 99%

Ultrasound and magnetic resonance imaging in Crohn's disease: a comparison

et al. 2001

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The objective of this retrospective study was to compare MRI of the abdomen with ultrasound of the abdomen and gastrointestinal tract in patients with Crohn's disease. Forty-six patients were included in the study. We analyzed the localization of Crohn's lesions, the number of affected bowel segments, the number of stenoses, and the presence of abscesses, fistulae, and any additional findings. Findings were verified by means of one or more of the following: enteroclysis; surgical findings; and colonoscopy. The results show that MRI is superior to ultrasound in the localization of affected bowel segments (sensitivity: MRI 97.5%; US 76%) and in recognizing fistulae (sensitivity: MRI 87%; US 31%), stenoses (sensitivity: MRI 100%; US 58%) and abscesses (sensitivity: MRI 100%; US 89%). Magnetic resonance imaging of the abdomen should be obtained to clarify discrepant clinical and sonographic findings. In addition, despite its higher cost, MRI of the abdomen is justified in patients in whom Crohn's lesions are known or suspected in anatomic areas proximal to the terminal or neoterminal ileum and in cases with suspicion of fistulae and abscesses.

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“…2 Based on the aforementioned pathophysiologic theory, we speculated that conditions in which low intracolonic pressures prevail and a thickened bowel wall is present would be associated with a lower risk for developing diverticulosis. Therefore, the aim of this study was to compare the prevalence of diverticulosis among patients suffering from chronic colitis, a condition that is associated with less formed stools, particularly during disease flare-up, and likely with low intracolonic pressure, combined with the presence of a thickened bowel wall as a result of the inflammation, 5,6 with the prevalence of diverticulosis among healthy, age-matched controls.…”

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confidence: 99%