1992
DOI: 10.1016/0006-8993(92)91135-2
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Magnetic resonance imaging of neural transplants in rat brain using a superparamagnetic contrast agent

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Cited by 53 publications
(33 citation statements)
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“…Labeling of cells with MR contrast agent provides a tool to detect and track cells with MRI (Bulte et al, 2002;Norman et al, 1992). Several methods for cellular incorporation of MR contrast agent exist, as has been reviewed by Bulte et al (2002).…”
Section: Cell-specific Magnetic Resonance Imagingmentioning
confidence: 99%
“…Labeling of cells with MR contrast agent provides a tool to detect and track cells with MRI (Bulte et al, 2002;Norman et al, 1992). Several methods for cellular incorporation of MR contrast agent exist, as has been reviewed by Bulte et al (2002).…”
Section: Cell-specific Magnetic Resonance Imagingmentioning
confidence: 99%
“…MRI, with its high spatial resolution, is the ideal modality for in vivo cell tracking. Tagging cells with superparamagnetic iron oxide (SPIO) nanocomposites has been shown to induce sufficient MR cell contrast for in vivo imaging of neural cell migration (8,9). Previous studies have demonstrated its application to track stem cells after stroke, but these were done with non-human stem cells and lacked in-depth analysis of the SPIO effect on stem cell biology (10, 11).…”
mentioning
confidence: 99%
“…We hypothesized that tagging grafted cells with a magnetic label might allow magnetic resonance (MR) tracking of their migratory capacity, not unlike an earlier MR microscopy study that used labeled progeny cells to follow cell movements and lineages in the developing embryo (7). Magnetically labeled cells previously have received interest to study neural grafting procedures (8,9) and cellular trafficking (10)(11)(12)(13) by MR imaging.…”
mentioning
confidence: 99%