Magnetic Resonance Imaging of Rare Intracranial Neoplasms – Role of the In Vivo 1 H Spectroscopy in the Radiological Differential Diagnostics

Abstract

The small number of patients made statistical analysis impossible. However, at present, it seems that neuroradiological diagnosis should not rely on MR spectroscopy alone.

MRS study of meningeal hemangiopericytoma and edema: A comparison with meningothelial meningioma

“…Hypotaurine (HTau) is detected only in meningioma, whereas OH-But is present only in HPC. Overall, these data are consistent with published studies (19)(20)(21). It is difficult to quantify the Tau content in HPC due to overlapping signal from α-, β-Glc.…”

“…In fact, we observed a high variability of PC/Cho in our meningioma set. It is to be noted that HR-MAS MRS allows the detection of Ala in HPC, which has been reported to be absent (19,20). This is probably due to the higher sensitivity of HR-MAS MRS with respect to in vivo MRS.…”

“…Due to their more aggressive behavior, intracranial HPCs require different management and a correct diagnosis is critical (15)(16)(17). However, data from two studies (18,19) suggest that the discrimination between HPC and meningiomas seems to be possible by using in vivo MR spectroscopy (MRS) and the authors hypothesized that the discrimination can be obtained based on the much higher levels of myo-inositol (Myo) in the HPCs. Moderately…”

Differential diagnosis of intracranial meningiomas based on magnetic resonance spectroscopy

“…Likewise, MRS seems to be helpful in diagnosing haemangiopericytomas, tumours that are virtually indistinguishable from meningiomas on MRI [30]. The hae mangiopericytoma spectrum has the same characteristics as that of meningioma; however, there is no Ala signal, whilst a high mI peak is present [31] ( Figs.…”

Magnetic resonance spectroscopy in intracranial tumours of glial origin

“…One of its particular applications is magnetic resonance spectroscopy in vivo (MRS). To date, a number of reports have presented a correlation between MRS spectra and neuropathology of brain tumours [1][2][3][4][5][6][7]. This method proved to be helpful in in vivo grading of gliomas [8][9][10][11], discrimination between lymphomas and gliomas [12,13], metastases and gliomas [14], as well as neoplasms and non-neoplastic lesions [15,16].…”