Magnetite/dextran-functionalized graphene oxide nanosheets for in vivo positive contrast magnetic resonance imaging

Abstract

In vivo positive contrast MRI by magnetite/dextran-functionalized graphene oxide (SPIO-Dex-FGO) as compared to Magnevist® (the right rat).

ZnO quantum dots-graphene composites: Formation mechanism and enhanced photocatalytic activity for degradation of methyl orange dye

“…The height profile of the line marked in the AFM image indicates monolayer graphene sheets with 0.8 nm thickness. It is widely accepted that due to the presence of oxygen functionalities on the surface of GO, its thickness is around 0.8-1.1 nm, which is somewhat thicker than the 0.4 nm thickness of graphene sheet [38]. In order to quantitatively evaluate the surface concentrations of carbon-bonded functional groups, the peak area of oxygen-containing bonds and C/O ratio were calculated and inserted in Table 1.…”

Single step synthesis, characterization and applications of curcumin functionalized iron oxide magnetic nanoparticles

“…1,2 In addition, Fe 3 O 4 magnetic nanoparticles (MNPs) have shown promising application as materials of interest for ferrofluids, 3,4 hyperthermia, 5 magnetic resonance imaging (MRI), 6,7 high-density information storage, 8 and targeted drug delivery labeling. 9 A variety of methodologies including coprecipitation, sol-gel method, thermal decomposition, microemulsion and hydrothermal synthesis have been reported for the synthesis of Fe 3 O 4 MNPs, and further advancement in the synthesis of such materials is still on-going due to their outstanding potential in variety of applications.…”

Biocompatible and Stable GO-Coated Fe3O4 Nanocomposite: A Robust Drug Delivery Carrier for Simultaneous Tumor MR Imaging and Targeted Therapy

“…According to a previous report, negative contrast agents can be improved through modification with dextran to reduce the partial volume effect. In our study, we used a high-resolution MRI machine to achieve the same improvement, as shown in Figure .…”

“…However, this type of high-resolution MRI machine is expensive and not commonly used in hospitals. Thus, we intend to make further modifications to our nanocomposites to facilitate clinical applications …”

“…These results suggest that the FA-Fe 3 O 4 @nGO-DOX composite could be used as an MRI contrast agent, with a long lifetime, for diagnosis and detection of small tumors that express FR. According to a previous report, 54 negative contrast agents can be improved through modification with dextran to reduce the partial volume effect. In our study, we used a highresolution MRI machine to achieve the same improvement, as shown in Figure 8.…”