Main Agents of Opportunistic Infections of Genitourinary Tracts and Their Antibiotic Resistance

Abstract

Today the one of most important medical-social problems is a growing antibiotic resistance of opportunistic infectious agents. Aim of research: the dynamic observance of antibiotic resistance of opportunistic pathogens – infectious agents of genitourinary tracts under conditions of venereological clinic. The study included 2205 patients with inflammatory diseases of genitourinary tract, who were on the stationary treatment at the department of venereology of SI “IDV NAMS of Ukraine”. Bacteriological studies for isolation of conventionally pathogenic microorganisms with determination of sensitivity of separated laboratory strains to antibacterial drugs of the different groups were carried out using the methods of classic bacteriology. It was demonstrated, that the composition of microbiocenosis of genitourinary tract in patients with infections, caused by conventionally pathogenic microorganisms was characterized by the prevalence of aerobic representatives of Enterobacteriaceae and Staphylococcaceae families that formed associations both between each other and with representatives of other taxonomic groups. The analysis of antibiotic sensitivity of separated strains testifies to the necessity of permanent microbiological monitoring of opportunistic infectious agents for elaborations of the regimes of rational antibacterial therapy.

Monitoring of distribution of antibiotic-resistant strains of microorganisms in patients with dysbiosis of the urogenital tract

“…But in cases of associations of microorganisms during bacteriological inoculations, the question is what effective antibiotics to chose, because pathogens of inflammation may belong to different taxonomic groups and have differences in the susceptibility to antibacterial preparations. Over 70% of infections are caused by microorganisms resistant to several or a number of antibiotics (Bondarenko et al, 2017;Drago et al, 2020).…”