Making sense: Determining the parameter space of electrical brain stimulation

Murphey, Dona K.

doi:10.1073/pnas.1520704112

Cited by 2 publications

(1 citation statement)

References 19 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The axons of hypothalamic oxytocin neurons project to several regions associated with inequity aversion, including the amygdala, hippocampus, ACC and mPFC [26]. Several reports have investigated the effect of oxytocin on prosocial behaviors related to inequity aversion [27]. The administration of oxytocin was found to alter the subjective evaluation of unfairness [28] and money allocation with others in economic games such as the trust game and ultimatum game [13,17,24,29].…”

Section: Introductionmentioning

confidence: 99%

Interactive effects of OXTR and GAD1 on envy-associated behaviors and neural responses

et al. 2019

View full text Add to dashboard Cite

Inequity aversion (negative feelings induced by outcome differences between the self and other) plays a key role in human social behaviors. The neurotransmitters oxytocin and GABA have been implicated in neural responses to inequity. However, it remains poorly understood not only how individual genetic factors related to oxytocin and GABA affect the neural mechanisms behind inequity aversion, but also how these genes interact. To address these issues, we examined relationships between genotypes, behavioral decisions and brain activities during the ultimatum game. We identified interactive effects between the polymorphisms of the oxytocin receptor gene (OXTR) and glutamate decarboxylase 1 gene for GABA synthesis (GAD1) on envy aversion (i.e., disadvantageous inequity aversion) and on envy-induced activity in the dorsal ACC (dACC). Thus, our integrated approach suggested interactive genetic effects between OXTR and GAD1 on envy aversion and the underlying neural substrates.

show abstract