Male breast cancer: A retrospective study from a regional cancer center in northern India

Abstract

Over a 7‐year period from 1987 to 1993, 41 male breast cancer patients were seen in the breast cancer clinic of the Institute Rotary Cancer Hospital (IRCH) at the All India Institute of Medical Sciences (AIIMS). Their mean age was 54.2 years; and duration of symptoms ranged from 1 to 84 months with a mean of 15.1 months. Breast lump was the commonest presenting symptom. Fine needle aspiration cytology (FNAC) was the commonest diagnostic procedure. The TNM stage distribution was stage I, 5; stage II, 13; stage III, 17; and stage IV, 6. Radical mastectomy (25/36) was the commonest surgical procedure. Locoregional radiotherapy was given in 15 patients. Thirty patients received systemic adjuvant therapy (chemotherapy or tamoxifen, or a combination of the two). Local or distant recurrence occurred in 8 patients (8/31, 28.3%). Actuarial overall and disease‐free survival was 100% and 80.1% at 2 years and 91.7% and 66.7% at 4 years, respectively. On univariate analysis, axillary lymph node status and age were found to affect disease‐free survival significantly. Advanced stage of disease at presentation is common in Indian patients and will continue to influence treatment policies. Neoadjuvant chemotherapy needs to be evaluated for locally advanced tumors to improve outcome. Multicentric studies are necessary to define the relative roles of tamoxifen and chemotherapy for adjuvant treatment. © 1996 Wiley‐Liss, Inc.

Clinical trends and outcomes of male breast cancer: Experience of a tertiary oncology centre in India

“…Consistent with previous literature 18,19 , the most common presentation was a painless sub-areolar lump detected in 87.9% of our patients. The most common location in women is the upper outer quadrant.…”

“…Majority of MBCs are of infiltrating ductal histology 12 and are estrogen receptor positive. 17 Most commonly they present with lump in breast 18,19 with positive axillary nodes. 20,21 As in women, MBC survivorship is highly dependent on grade of tumors with grade 3 fairing much poorly than lower grades.…”

Male breast cancer: a review of clinical management

“…The mean age of presentation is mostly in sixties but ranging from twenties to nineties. The duration of symptoms before diagnosis is declining [54] but there are major geographical differences ranging from a mean of 1-8 months [52,55,56] in western world to a mean of 12-15 months in the Asian-African continents and hence a later stage of presentation [57,58].…”

Men With Breast Cancer Have Better Disease-Specific Survival Than Women

“…Previous reviews have reported that axillary node involvement was an important predictor of prognosis, and in some studies it has been the most important factor. 10,21,22 Other studies have found that the previously reported poor outcomes in male breast cancer patients were thought to arise from a delay in diagnosis, later treatment, and advanced stage at diagnosis. 10,15 A delay in diagnosis of 18 months has been previously reported.…”