Male breast cancer: Austrian experience

Stierer, M.; Rosén, Harald; Weitensfelder, W; Hausmaninger, H.; Teleky, B.; Jakesz, R.; Fruhwirth, H.; D�nser, Martina; Beller, S.; Haid, A.; T�chler, Heinz

doi:10.1007/bf00295904

Cited by 72 publications

(50 citation statements)

References 30 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The most common presenting symptoms in male breast cancer patients are a painless subareolar lump, nipple retraction, and bleeding from the nipple (Stierer et al 1995;Goss et al, 1999;Giordano et al, 2002). As in women, there is a slight preponderance of left-sided versus right-sided disease (Scott-Conner et al, 1999).…”

Section: Discussionmentioning

confidence: 99%

Perceptions and Opinions about Male Breast Cancer and Male Breast Self-Examination: A Qualitative Study

Al-Naggar

Al-Naggar²

2012

Asian Pacific Journal of Cancer Prevention

View full text Add to dashboard Cite

Objective: While the relatively common nature of female breast cancer has resulted in a high level of general awareness, male breast cancer is still comparatively unknown to the general public and to healthcare professionals. The objective of this study is to explore the perceptions and opinions about male breast cancer and male breast self-examination among male university students. Methodology: In-depth interviews were conducted among 36 male university students from the Management and Science University, Malaysia, selected by simple random sampling. The themes of the interview were: knowledge of male breast cancer and male breast self-examination, sources of knowledge and attitudes towards male BSE. The data obtained were classified into various categories and analyzed manually. Results: The majority of participants mentioned that there is a low possibility for males to get breast cancer. They also believed that the cause of breast cancer among men is due to the carcinogens from cigarettes. The majority of participants mentioned that they know about breast self-examination from the mass media and that the presence of a lump in the breast is the main symptom of breast cancer in men. The majority of participants mentioned that they encourage their family members to practice breast self-examination but considered that BSE is not important for men because they have a low probability of getting breast cancer. Conclusions: Misconceptions regarding male breast cancer and breast self-examination among men still exist among male university students. Therefore especial attention should be given to educate men about male breast cancer and male BSE.

show abstract

Section: Discussionmentioning

confidence: 99%

Perceptions and Opinions about Male Breast Cancer and Male Breast Self-Examination: A Qualitative Study

Al-Naggar

Al-Naggar²

2012

Asian Pacific Journal of Cancer Prevention

View full text Add to dashboard Cite

show abstract

“…The most common presentations are painless palpable mass, skin ulceration, and nipple retraction or discharge in approximately 75% of the cases, similar to women (7,(50)(51)(52)(53). Since the breast tissue in men is undersized, the nipple is mostly involved at early stages.…”

Section: Symptoms Clinical Signs and Manifestationsmentioning

confidence: 99%

“…A limited number of prospective, randomized clinical studies exist, which indicate the benefit of adjuvant systemic therapy for MBC (88). On the other hand, decreased recurrence and mortality rates have been reported with adjuvant CT in retrospective studies (53,89). Furthermore, the prognosis and response rates to therapy in with metastatic MBC are similar to those of women.…”

Section: Chemotherapy (Ct)mentioning

confidence: 99%

Male Breast Cancer

Yalaza¹,

2016

View full text Add to dashboard Cite

IntroductionOver the past two decades, major improvements have been achieved in the understanding of breast cancer, and cure can be offered if the disease is diagnosed at an early stage. However, the disease is more often diagnosed at more advanced stages (3 or 4) in men, in contrast to women. Its rarity among men as well as lack of awareness leads to its detection at later stages. Randomized studies cannot be carried on due to the low incidence of breast cancer in males, with only a few published prospective therapeutic studies in the literature. While the information on male breast cancer (MBC) was obtained from retrospective studies, the recommendations for treatment were derived from studies conducted on female breast cancer (1). This review presents the frequency, etiology, clinical-pathological characteristics and treatment approaches for the rare MBC. Epidemiology-EtiologyMale breast cancer is rare and constitutes 0.5-1% of all patients with breast cancer. The reason of the low incidence rate in men is the relatively low amount of breast tissue along with the difference in their hormonal environment. Even though breast tissue is less in men as compared to women, the factors that influence malignant changes are similar. The Surveillance, Epidemiology and End Result (SEER) Program reported that the incidence of breast cancer was highest at ages 52-71 during 1973-2000, whereas the peak incidence in males was 71 years (2). In fact, some authors state that MBC imitate the behavioral pattern of post-menopausal female breast cancer. The incidence of breast cancer in males and females has increased in the past 25 years. International Association of Cancer Registries (IACR) emphasized this increase and stated that the incidence of female breast cancer increased by 20%, while breast cancer-related deaths increased by 14%. The SEER data also showed that the rate that was 1.1 for 100.000 men in the mid-1970s and raised to 1.44 for 100.000 men by 2010 (3). In USA, 2240 men were diagnosed with breast cancer within the year 2013. The lifetime rate of diagnosis with male breast cancer is 1 in 1000. According to the IACR Turkey data, 0.37% of all cancer types among males are breast cancer (4, 5). IACR has published its new cancer estimates for the year 2012. The most recent cancer estimates for 28 cancer types in 184 countries, which record cancer data, have been made available for users on the GLOBOCAN 2012 website (6).The rate of presentation with advanced stage breast cancer has been decreasing in men. As a matter of fact, a study conducted in 1995 reported the rate of Stage 1-2 disease on diagnosis as 70%, whereas it was reported as 67% in 2010 and 82% in 2015 (7-9). MBC constitutes less than 1% of male cancers and it has a varying rate of incidence across different geographies and ethnic groups (10, 11). Its annual prevalence in Europe is 1 in 10.000 men and these cases constitute less than 1% of all patients with breast cancer (4). However, this rate is above 6% in Central African countries (12). This relatively hig...

show abstract

“…Such data were reported before the systematic use of sentinel node biopsy in females. Omission of axillary dissection led to increased regional nodal relapses rates in MBC (12,13).…”

Section: Resultsmentioning

confidence: 99%

“…Younger patients were more likely to receive adjuvant radiotherapy (30). Some authors used boost to the chest wall, for incomplete resection or tumor classified as T4 (11,13,27). After partial mastectomy, radiation therapy was not systematically given.…”

Section: Resultsmentioning

confidence: 99%

Should Adjuvant Radiation Therapy Be Systematically Proposed for Male Breast Cancer? A Systematic Review

Jardel

Vignot²,

Cutuli

et al. 2018

View full text Add to dashboard Cite

Breast cancer in males is infrequent, representing 1% of all breast carcinomas, and less than 1% of all male cancers (1, 2), even if its incidence seems to be increasing (3-7). All studies regarding male breast cancer (MBC) are retrospective and specific recommendations are sparse. The general management of non-metastatic MBC is usually based on guidelines for female breast cancer (FBC). Surgery, chemotherapy and hormonal therapy are based on classical prognostic factors. After mastectomy, which represents the majority of cases, locoregional irradiation for MBC remains controversial. Some institutions recommend systematic postmastectomy irradiation considering that MBC is intrinsically more aggressive than FBC and that the ratio of tumor size to gland could lead to minimal surgical margins; others suggest that the natural history of MBC resembles that of postmenopausal female breast cancer and that the aggressiveness is biased by a more advanced stage at diagnosis (1, 2, 4). Institutions base their recommendations for MBC based on data established for females. We evaluated clinical practices and outcomes with respect to radiation therapy in MBC treated with locoregional irradiation in the adjuvant setting using a systematic literature review. Materials and MethodsOur systematic review of the literature was based on the Preferred Reporting Items for Systematic Reviews and meta-Analysis (PRISMA) recommendations (http://www.prisma-statement.org/). Data were selected from a search on PubMed during the period 1976 to 2017 and from references in identified articles, using the following search terms: "breast cancer", "men", "male", "radiotherapy"; articles published in English or French were included. Relevant articles were selected with the following inclusion criteria: non metastatic MBC, an original study with more 23This article is freely accessible online.

show abstract

Male breast cancer: Austrian experience

Cited by 72 publications

References 30 publications

Perceptions and Opinions about Male Breast Cancer and Male Breast Self-Examination: A Qualitative Study

Perceptions and Opinions about Male Breast Cancer and Male Breast Self-Examination: A Qualitative Study

Male Breast Cancer

Should Adjuvant Radiation Therapy Be Systematically Proposed for Male Breast Cancer? A Systematic Review

Contact Info

Product

Resources

About