Male Erectile Dysfunction and Health-Related Quality of Life

Sánchez-Cruz, José Juan; Cabrera-León, Andrés; Martín‐Morales, Antonio; Fernández, A.; Burgos, R; Rejas, Javier

doi:10.1016/s0302-2838(03)00215-x

Cited by 171 publications

(120 citation statements)

References 21 publications

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“…Medical treatment is the most common solution to ED; 5-PDE inhibitors are commonly used as an initial treatment [2,3]. ED is an important aspect of sexual dysfunction, and occasionally male patients with sexual dysfunction are treated with multi-drug treatment and psychotherapy.…”

Section: Discussionmentioning

confidence: 99%

“…The first line of treatment is oral medication therapy; specifically, 5-phosphodiesterase (PDE) inhibitors such as sildenafil, tadalafil and vardenafil are generally prescribed by urologists to treat ED [2,3]. Although earlier studies showed strong efficacy of 5-PDE inhibitors in ED irrespective of etiology, phytotherapies have recently been given more attention as natural alternatives to synthetic pharmaceuticals and have become more widely available.…”

Section: Introductionmentioning

confidence: 99%

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Effects of tissue-cultured mountain ginseng (Panax ginseng CA Meyer) extract on male patients with erectile dysfunction

Kim¹,

Jeon²,

Hahn³

et al. 2009

Asian J Androl

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Korean ginseng and mountain ginseng (Panax ginseng CA Meyer) are important traditional herbal plants whose ginsenosides are generally accepted as serving to improve sexual functions, such as penile erection. We investigated the effects of tissue-cultured mountain ginseng extract (TMGE) on male patients with erectile dysfunction (ED). A double-blind, placebo-controlled study was conducted with 143 patients experiencing ED. Over the course of 8 weeks, one group took 1 000 mg of TMGE twice a day, and the other group took 1 000 mg of placebo twice a day. The effects of the TMGE and the placebo were analyzed using the Korean version of the International Index of Erectile Function (IIEF) questionnaire. A total of 86 patients completed 8 weeks of treatment. The scores on the five domains of the IIEF after medication were significantly higher than the baseline scores in the group treated with TMGE (P < 0.05), whereas no significant improvement was observed in the placebo group (P > 0.05). Erectile function and overall satisfaction scores after medication were significantly higher in the TMGE group than in the placebo group (P < 0.05). Erectile function of patients in the TMGE-treated group significantly improved, suggesting that TMGE could be utilized for improving erectile function in male patients.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Effects of tissue-cultured mountain ginseng (Panax ginseng CA Meyer) extract on male patients with erectile dysfunction

Kim¹,

Jeon²,

Hahn³

et al. 2009

Asian J Androl

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“…A similar result was also reported by a study carried out in Spain. 21 In that study, a significantly negative association between physical summary component of health-related quality of life (HRQoL) and ED was observed. In addition, a multicenter clinical study has also found a significant correlation between improvement of erectile function and psychological manifestations in ED patients treated with a 10-week, open-label and flexible-dose of sildenafil (50 mg, adjustable to 25 or 100 mg).…”

Section: Discussionmentioning

confidence: 82%

Association among hypogonadism, quality of life and erectile dysfunction in middle-aged and aged male in Taiwan

Hwang

Tsai³

et al. 2006

Int J Impot Res

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The association between hypogonadism, quality of life (QoL), and erectile dysfunction (ED) among the middle-aged and aged male in Taiwan is evaluated. A total of 680 study subjects aged X40 years old were recruited from Northern (n ¼ 276), Middle (n ¼ 238), and Southern (n ¼ 202) Taiwan, respectively. ED was diagnosed by score of International Index of Erectile Function (IIEF-5). Taiwan version questionnaire for QoL includes domain 1 (physical domain), domain 2 (psychological domain), domain 3 (social relationship domain), and domain 4 (environmental domain) was used to measure QoL. Blood hormones, including FSH, LH, Prolactin, SHBG, total testosterone (TT), calculated free testosterone (cFT), and bioavailable testosterone (Bio-T), were determined. Logistic regression analysis was used to estimate crude and multivariate-adjusted odds ratio of risk factors and its 95% confidence interval. A significantly inverse association between concentration of serum cFT and Bio-T, and severity of ED was observed. Scores of QoL of Domain 1-4 were significantly decreased with the increament of severity of ED. Significant correlations were found between IIEF scores and four domains of QoL, respectively. After adjustment for age, cFT and Bio-T, study subjects with ED (IIEFp21) would have significantly high risk of low level of QoL in four domains. In conclusion, a significant association between low levels of serum calculated cFT, Bio-T, and severity of ED was found. In addition, abnormal erectile function significantly associated with low level of QoL in four domains.

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“…3,4,[24][25][26][27] Yaşlanma ile birlikte prevalansı artan ED, aynı zamanda yaşlı erkeklerde yaşam kalitesini düşüren seksüel disfonksiyonun en sık görülen formudur. 28,29 Ancak ED, ölümcül ve/veya günlük aktiviteyi kısıt-layan bir hastalık değildir. Bazı hastalar, bu nedenlerle hekime müracaat etmeyi gerekli görmemiş olabilir.…”

Section: Sonuçunclassified

Reasons of Turkish Males with Erectile Dysfunction for Not Presenting to Urology Clinics

Bayraktar¹,

Atun²

2012

Turkiye Klinikleri J Med Sci

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Male Erectile Dysfunction and Health-Related Quality of Life

Cited by 171 publications

References 21 publications

Effects of tissue-cultured mountain ginseng (Panax ginseng CA Meyer) extract on male patients with erectile dysfunction

Effects of tissue-cultured mountain ginseng (Panax ginseng CA Meyer) extract on male patients with erectile dysfunction

Association among hypogonadism, quality of life and erectile dysfunction in middle-aged and aged male in Taiwan

Reasons of Turkish Males with Erectile Dysfunction for Not Presenting to Urology Clinics

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