Malignant priapism in metastatic prostate cancer: A late event occurring early

Barrett-Campbell, Odeth; Petkovska, Iva; Slovin, Susan F.

doi:10.1016/j.eucr.2018.03.001

Cited by 2 publications

(1 citation statement)

References 3 publications

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“…In prostate cancer another option is hormone deprivation therapies which cut the source of cancerous cells growing stimulator such as antiandrogens, gonadotropin-releasing hormone (GnRH) agonists and 5α-reductase inhibitors, however their efficacy are not approved yet (13). Although pelvic radiotherapy have shown promising outcome, it can be accompanied by anatomical changes which might be troublesome for voiding of the patients (14). Hormonal therapies, on the other hand, have shown that they can affect the prognosis of prostate cancer and prolong the life expectancy (15).…”

Section: Discussionmentioning

confidence: 99%

Priapism as The Initial Presentation of Prostate Cancer Recurrence: A Case Report and Review of the Literature

Ebrahimi

2024

IJCCR

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Introduction: Prostate cancer is one of the two most common non-cutaneous cancers in men. Its presentation might have unusual symptoms, which could have caused the wrong initial diagnosis. Case Presentation: This study presents a case of prostate cancer complaining of persistent pain and erection of the penis. He had been treated with radical prostatectomy five years before his presentation. The patient had not followed his treatment for the cancer for the last four years. The patient was admitted to the hospital, and urgent imaging of the pelvis with magnetic resonance imaging showed extensive involvement of lymph nodes and corpus cavernosa. Management started with the combination of anti-androgenic and radiotherapy, which was effective and caused significant clinical improvement in the patient’s condition and improved laboratory and radiologic markers. Discussion: Prostate cancer recurrence can present with unusual symptoms considering its slow progression and involvement of the various structures. Malignant priapism is the involvement of the cavernosal system by a solid tumor. This is an indicator of a poor prognosis, and most patients' life expectancies are shorter than one year. Clinical Key Message Priapism can have a wide range of etiologies, and it can also be an indicator of malignancy progression through the genitourinary systems. In patients with a history of prostate cancer or those with a risk of this malignancy presented by priapism, appropriate diagnostic evaluation regarding this cancer should be performed. More importantly, patients treated for prostate cancer should be followed up regularly, and it should be mentioned that this cancer can slowly recur without any symptoms until it reaches a high stage.

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Section: Discussionmentioning

confidence: 99%