Malignant Spinal Cord Compression

MacDonald, Alan G.; Lynch, Daniel F.; Garbett, Ian; Nazeer, Nauzan

doi:10.4997/jrcpe.2019.217

Cited by 18 publications

(12 citation statements)

References 13 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“….Metastatic spinal cord compression (MSCC) remains a challenging oncological emergency and requires effective multidisciplinary management for optimal effects on patients' morbidity and quality of life (57) .…”

Section: Table (2) Showed Percent Distribution Of Levels and Mean Sco...mentioning

confidence: 99%

Effect of Educational Program for Nurses on Clinical Outcomes of Cancer patients with Metastatic Spinal Cord Compression

Khalil

Diab

El-Din

et al. 2022

Tanta Scientific Nursing Journal

View full text Add to dashboard Cite

Background: Spinal cord compression is a common oncological emergency that requires early detection and prompt treatment as it can result in permanent neurological deficit. Nurses are often involved in supporting patients living with cancer. They may be the first healthcare professional to recognize the "red flag" symptoms of MSCC. Early recognition by the nurses will prompt timely investigation, treatment and potentially reduce the risks of patient's having a permanent disability. Aim: To determine the effect of educational program for nurses on clinical outcomes of cancer patients with Metastatic Spinal Cord Compression. Method: Design, A quasi-experimental research design was utilized in this study .Setting, the study was conducted at Clinical Oncology and Nuclear Medicine Department at Tanta University Hospital.. Subjects: convenience sample of 40 nurses and 30 cancer patients. Tools: Tool I: Structured Interview Schedule. Tool II: Nursing Care Observational Checklist. Tool III: Patient's Assessment Structured Interview Schedule. Tool (IV): Patient's Outcomes sheet. Results : a highly significant difference was noticed related to the total level of knowledge and practice of studied nurses through periods of study (pre-immediate and post one month assessment periods) with P value= 0.0001.A highly significant difference was found related to the total level of knowledge for the studied patients thought the periods of the study as P value =0.0001.Conclusion:The oncology nurse's knowledge and practice improved significantly after attendance of program sessions. Recommendation: Conduct periodical training programs, workshops and seminars for oncology nurses to refresh their knowledge, and practice about metastatic spinal cord compression and its early detection and management.

show abstract

Section: Table (2) Showed Percent Distribution Of Levels and Mean Sco...mentioning

confidence: 99%

Effect of Educational Program for Nurses on Clinical Outcomes of Cancer patients with Metastatic Spinal Cord Compression

Khalil

Diab

El-Din

et al. 2022

Tanta Scientific Nursing Journal

View full text Add to dashboard Cite

show abstract

“…MSCC is a complication of cancer that occurs in 5-10% of patients and can particularly complicate the final stages of their disease [2]. However, it could also be the presenting symptom of a malignancy; in a retrospective cohort study, 21% of patients with MSCC had no diagnosis of cancer within the last year [3].…”

Section: Introductionmentioning

confidence: 99%

Management of Metastatic Spinal Cord Compression in Secondary Care: A Practice Reflection from Medway Maritime Hospital, Kent, UK

Shah

Kutka

Lees

et al. 2021

JPM

View full text Add to dashboard Cite

Introduction: Malignant spinal cord compression (MSCC) is one of the most devastating complications of cancer. This event requires rapid decision-making on the part of several specialists, given the risk of permanent spinal cord injury or death. The goals of treatment in spinal metastases are pain control and improvement of neurological function. There can be challenges in delivering prompt diagnosis and treatment in a secondary care setting. We have reflected on the experience of managing MSCC in a district general setting. Aim: Our retrospective audit identified 53 patients with suspected MSCC who entered the relevant pathway from April 2017 to March 2018 at Medway, United Kingdom (UK). Our audit standards were set out by Medway Maritime Hospital and Maidstone and Tunbridge Wells NHS Trust MSCC working group members, using a combination of published evidence and best practice. Results: The patients with suspected MSCC were 53 and 29 of them (54.7%) had confirmed MSCC. The most common malignancies within the confirmed MSCC were lung (11 patients, 37.9%), breast (5 patients 17.2%), and renal (3 patients, 10.3%), followed by prostate, myeloma and carcinoma of unknown primary (2 patients (6.9%) each), as well as pancreatic, colorectal, lymphoma and, bladder (1 patient (3.4%) each). A magnetic resonance imaging (MRI) scan was performed in 48 patients (90.5%); the majority (31 patients, 64.6%) underwent the MRI within the first 24 h, whereas 3 patients had the investigation between 24 and 72 h from the admission. Among the 29 patients with confirmed MSCC, 6 (20.6%) were treated with surgical decompression, while 20 (69%) received radiotherapy (RT) and 3 (10.3%) best supportive care, respectively. Median time to surgery was 5 days (ranged between 2 and 8 days), whereas for RT 44.4 h (ranged between 24 and 72 h). Finally, all 3 patients that decided on symptom control were referred to a palliative care team within the first 24 h following the MRI scan. Conclusions: MSCC is frequently presented outside tertiary care. This may cause subsequent delays in investigation, diagnosis, and treatment, which can be improved by following a fast track referral pathway.

show abstract

“…It is a feared complication in oncology patients due to its potential for severe pain, mechanical instability of the spine and permanent neurological deficits including weakness, sensory loss, and bladder and bowel dysfunction. Prompt recognition and early treatment are necessary for pain relief and preservation of neurological function [1][2][3][4][5].…”

Section: Introductionmentioning

confidence: 99%

“…MSCC is a time-sensitive diagnosis and is considered an oncological emergency [3,5]. If there are delays to treatment and compression is not relieved quickly, progressive irreversible neurological dysfunction can occur.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

State-of-the-Art Imaging Techniques in Metastatic Spinal Cord Compression

Kuah

Vellayappan

Makmur

et al. 2022

Cancers

View full text Add to dashboard Cite

Metastatic Spinal Cord Compression (MSCC) is a debilitating complication in oncology patients. This narrative review discusses the strengths and limitations of various imaging modalities in diagnosing MSCC, the role of imaging in stereotactic body radiotherapy (SBRT) for MSCC treatment, and recent advances in deep learning (DL) tools for MSCC diagnosis. PubMed and Google Scholar databases were searched using targeted keywords. Studies were reviewed in consensus among the co-authors for their suitability before inclusion. MRI is the gold standard of imaging to diagnose MSCC with reported sensitivity and specificity of 93% and 97% respectively. CT Myelogram appears to have comparable sensitivity and specificity to contrast-enhanced MRI. Conventional CT has a lower diagnostic accuracy than MRI in MSCC diagnosis, but is helpful in emergent situations with limited access to MRI. Metal artifact reduction techniques for MRI and CT are continually being researched for patients with spinal implants. Imaging is crucial for SBRT treatment planning and three-dimensional positional verification of the treatment isocentre prior to SBRT delivery. Structural and functional MRI may be helpful in post-treatment surveillance. DL tools may improve detection of vertebral metastasis and reduce time to MSCC diagnosis. This enables earlier institution of definitive therapy for better outcomes.

show abstract

Malignant Spinal Cord Compression

Cited by 18 publications

References 13 publications

Effect of Educational Program for Nurses on Clinical Outcomes of Cancer patients with Metastatic Spinal Cord Compression

Effect of Educational Program for Nurses on Clinical Outcomes of Cancer patients with Metastatic Spinal Cord Compression

Management of Metastatic Spinal Cord Compression in Secondary Care: A Practice Reflection from Medway Maritime Hospital, Kent, UK

State-of-the-Art Imaging Techniques in Metastatic Spinal Cord Compression

Contact Info

Product

Resources

About